AlphaFold Unofficial

By far the best scientific community on the planet. Feels great leaving Mordor for Bluer Skies! #science

Women deserve authority equal to the responsibility they carry. The ability to set priorities, direct resources, and act on their expertise should accompany the work they are expected to deliver. GatherVerse S.H.E. Summit 2027 Site gatherverse.org/she2027 May our gather be well.

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Every region has women leading and solving humanity's greatest challenges. Their contributions deserve global recognition. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026/ May our gather be well.

No two women experience the world in the same way. Her life experiences tell a different human story. Every story expands AI's view of humanity. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well.

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The next frontier may be defined by a woman whose voice has too often been overlooked. She belongs here. Site gatherverse.org/women-ai-2026 May our gather be well.

In one of the most consequential chapters of human innovation, greater visibility for women leaders matters more than ever. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well

She brings authorship to artificial intelligence. A leader. She brings critique, technical fluency and strategic force. Original command. The future of AI must recognize her as central to the work. Non negotiable. Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026/

The future is too far away for women to begin to lead. Women are leading AI, across all industries. Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026/ May our gather be well.

She arrives as author, builder, and strategist. She leads in the frontier of innovation. Women leaders belong where power is defined. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well

is difficult to think of any part of life untouched by a woman's hand. As AI becomes prevalent in our world, more women are needed at the decision making table: their leadership, experiences, concerns, and contributions. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026

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Human progress reaches further when women are fully represented in innovation, research, funding, governance and leadership. The impact spans generations. __ Women’s AI Summit 2026 Site gatherverse.org/women-ai-2026 May our gather be well.

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Infuse intelligent machines with the perspectives and governance of women, and the future of all humanity will be protected __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well.

AI tools like AlphaFold have transformed the landscape of protein design in less than a decade. Meanwhile, organic chemists are still waiting for their own “AlphaFold moment” for predicting reaction recipes and routes for small-molecule synthesis. cen.acs.org/synthesis/ca... #chemsky 🧪

“A model of roads trained on only grid cities won’t properly predict the street plans of Rome or Boston.” An essay on the perils of AlphaFold and other kinds of AI in science cen.acs.org/pharmaceutic...

🧬 Figure Friday: Celebrating discoveries from the Protein Science community Can AI predict how proteins assemble? Ben Corry and colleagues show that AlphaFold can accurately predict the oligomeric states of many proteins, while also highlighting cases where predictions remain challenging.

John Jumper, the Nobel laureate behind AlphaFold, is leaving Google DeepMind after ~9 years for Anthropic. AlphaFold predicted 200M+ protein structures. Lands amid the talent war, days after Shazeer left Google for OpenAI. (Disclosure: we run on Anthropic's Claude.)

www.businessinsider.com/alphafold-jo... I don't know but I consider alpha fold pretty fucking important work.

Will AlphaFold et al. figure out how the genome works? Doubtful, says @philipcball.bsky.social. I think he's absolutely right. The genome is a complex adaptive system, w/ many layers of regulation and buffering—a "sensitive organ of the cell," said Barbara McClintock—in 1983!

A tough week for Google’s AI efforts. Along with losing the co-lead of Gemini to OpenAI, they are also losing the Nobel Prize winning lead of the AlphaFold project at DeepMind to Anthropic. He won a Nobel Prize in Chemistry in 2024 for using AI to predict 3D protein structures.

I’m not anti-tech or investment in tech. I’m excited about solar and AlphaFold and ocean monitoring. I love science; and I know the less flashy sides of science are suffering too. I just don’t want to see the humanities, our collective history, gutted to the point where it’s too late.

Isolation and characterization of broad-range Staphylococcus epidermidis sepunaviruses. Published Open Access and fee-free in Microbiology using a Publish and Read agreement: https://doi.org/10.1099/mic.0.001693 #Mic #PublishandRead

World-leading Aussie science fighting #AntimicrobialResistance! PhD student George Bouras added 17M bacterial protein predictions to the #AlphaFold database. This was made possible by a partnership between BioCommons & @pawseycentre.bsky.social to containerise #ColabFold on Setonix. Read more 🔗

Join us next week for our webinar, where we will demonstrate how to fetch and parse structural data using the AlphaFold Database (AFDB) APIs. Registration is free but essential to secure your place: www.ebi.ac.uk/training/eve... 🖥️🧬

🔬🚀 It's out! Run 100s of imaging experiments before touching a microscope. #VLab4Mic reproduces them in silico from PDB/AlphaFold to help you image right first time. From rockstars Damián Martínez & Bruno Saraiva, inaugural preprint of @mariodelr.bsky.social new lab www.biorxiv.org/content/10.6...

It always gets me the lengths people go to try to argue that LLMs and image generation models "aren't really AI", and then they point to "AI" things, and they're based on the same underlying tech. AlphaFold is built on latents, diffusion, *and* Transformers.

Before AlphaFold: Biology was like trying to understand machines without seeing their shapes. After AlphaFold: Scientists suddenly received a massive 3D blueprint library for life’s molecular machinery. This is how we can use AI for good. But w/o regulation, we risk harm to society.

STOP using ipTM for #AlphaFold PPI screens. * Artificially LOW when both full-length proteins have irrelevant, non-binding IDRs/domains. * If one protein is folded & other contains irrelevant IDRs or domains, the score is too HIGH bc of d0. * Use ipSAE or LIS. www.biorxiv.org/content/10.1...

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The future of successful companies belongs to those who create opportunities for women to lead, learn, and build innovations that drive the future of AI. Join us __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well.

Explore flexible macromolecule modeling with BilboMD! Access SAXS & AlphaFold-guided tools at SIBYLS & NERSC. Perfect for seamless workflow! PMID:42037134, Nucleic Acids Res 2026, @NAR_Open https://doi.org/10.1093/nar/gkag377 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Enter PHLEGM! 💻🧬 We developed the Phage Homomer Level Estimate and Generation Method to infer oligomeric state using AlphaFold-Multimer and interface quality assessment. We applied it to >22,000 sequences, revealing massive structural diversity. (2/n)

Day 1 of the Mendel Early Career Symposium! 100 international researchers gathered for networking, engaging talks & posters, keynote by @emmanuellebayer.bsky.social, & workshop on ChimeraX/AlphaFold. Thanks to the sponsors for supporting expanding horizons in #PlantBiology. #Mendel_ECR_26

Just published: The Hidden Handshake: How AlphaFold Solved a Decade-Long Mystery in Plant Immunity Over ten years in the making - generations of students and postdocs... Here's the structural basis of NLR activate-and-release, and, yes, we can engineer it. medium.com/p/the-hidden...

Doudna: “we don’t have the data…biological data are limiting…we need AI approaches that acknowledge this” Jennifer gives the example of Alphafold dependence on PDB at #cshlsymposium2026 noting that other areas like protein-NA complexes will need more data for AI to help.

Today, the AlphaFold2 paper reached the milestone of 50k citations according to Google Scholar! And AlphaFold3 will likely reach 15k citations tomorrow. Congratulations to the entire AlphaFold team, as well as to all the scientists who helped democratize protein structure prediction 🥳

When AlphaFold was released, there was a lot of talk that it marked the end of structural biology. That is far from the case. We will, I’m sure, hear similar comments with the emergence of AI co-scientist agents. AI is just a tool but It will never replace a scientist’s intuition & experience.

Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇

And then @googledeepmind.zpravobot.news.ap.brid.gy AlphaFold 3 came to the rescue! It predicted a high-confidence complex between Rx and NRC2, a sensor-helper pair in the NRC network. We consistently got confident predicitons across 10 independent models (ipTM = 0.76)!.

1/6 🧪 Big news for structural biology and AI: PDBe is now AI-native. We’ve built MCP Servers that connect the Protein Data Bank in Europe and the Alphafold Protein Structure Database directly to Claude and other MCP-compatible AI systems. Here’s what that unlocks 👇

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The system is broken. It needs to be reimagined.

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She rises where artificial intelligence meets gravity, wonder, and responsibility. Her leadership gives technology a finer sense of proportion. The machine age needs women who can keep power aligned with life. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026/ May our gather be well