Life scientist. AI, q-bio, systems biology.
Head, Open Science, @embo.org
Project Lead, @reviewcommons.org
@embopress.org
Loves 🎶 and plays the 🎻
Views my own
@qedscience.bsky.social has come up with a really controversial idea - an AI score for scientific impact. This trained score correlates with the impact factor of published preprints and the binning of papers into discrete quality bins accessed by independent scientists. Backlash in 3, 2, 1... (more)
It’s finally out! Together with @embopress.org and
@reviewcommons.org, we conducted a structured side-by-side comparison of human peer review and our AI scientific review (see thread 👇👇👇🔥).
It was a very cool experiment! The author-centric perspective makes a lot of sense.
An important next step is to benchmark multiple AI review platforms. Maybe this can also pave the way for benchmarking human peer review across journals and defining "quality features" of the peer review process.
It’s finally out! Together with @embopress.org and
@reviewcommons.org, we conducted a structured side-by-side comparison of human peer review and our AI scientific review (see thread 👇👇👇🔥).
It’s finally out! Together with @embopress.org and
@reviewcommons.org, we conducted a structured side-by-side comparison of human peer review and our AI scientific review (see thread 👇👇👇🔥).
Honored to be included in this reflection on 20 excellent years of MolSystBiol! From our first phosphotyrosine interactome in 2005 to proteome-wide networks - scale has grown exponentially. MS proteomics + AI is transforming systems-level understanding. Exciting times!
embopress.org/doi/pdf/10.1...
IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social@biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇
Very cool! I agree AI scientific review can be useful if it is transparent. It is all progressing very fast and will change everything. @qedScience @bioRxiv is a great first step. We are doing some human-based eval, so more soon from @EMBOPress @ReviewCommons with @qedScience. Watch this space ;-)
Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n
openrxiv.org/enabling-rev...
Last week on 11–12 Sep, together with our publishing partner @springernature.com, EMBO hosted a workshop "AI to advance open science publishing” in Heidelberg, DE. 🧪 Participants engaged in demonstrations and experiments using tools developed by Springer Nature and EMBO for innovation in publishing.
Two metrics designed for measuring the impact of investments in the specific context of life sciences (in brief: the metrics assess the potential increase in life years attributable to the investment & the improvement in quality of life) ➡️ www.nature.com/articles/s41...
A message of hope and optimism in these crazy times: Gewandhaus Orchestra open air concert, in Leipzig, Germany, right now: 20,000 people peacefully listening to the music of Max Bruch. Beautiful event.
An important, moving, and courageous piece from @juliosaezrod.bsky.social Respect!
"Becoming a patient has given me a new perspective on biomedical research. Despite my background in data analytics, I have found that I do not necessarily have access to the data or information I need..."
I wrote a short piece on how becoming an IgA Nephropathy patient has changed my perspective on biomedical research, developing an appreciation for the challenges in data interpretability & availability and the importance of patient engagement www.nature.com/articles/s41...
#TCTeAC - the Woodstock of Biology2 & #nightscience - was such an amazing event!! We met great scientists who creatively presented their high quality work. We dreamt and discussed in a very broad, open-minded setting. Talking science outside of our nutshell can be soo valuable - let's do this again!
Let's not be #TCTeAC "The Conference To END All Conferences", but a new format of many more such events. Depating science outside of our typical nutshell (scientifically and mentally) has great potential - we could have come up with 50+ project proposals together. Let's bring fun back to science :)
I'm late to review the "Illusion of Thinking" paper, so let me collect some of the best threads by and critical takes by @scaling01 in one place and sprinkle some of my own thoughts in as well.
The paper is rather critical of reasoning LLMs (LRMs):
x.com/MFarajtabar...
OK, self-replicating AI agents are perhaps not yet quite ready. Models still struggle to debug, a new Microsoft study reports.
Claude 3.7 Sonnet dominates. Will there be a Claude 3.7 Opus?
Preprint: arxiv.org/abs/2503.21557
Blog: www.microsoft.com/en-us/resear...
In the meantime, Claude 4 is out, and the progress continues, albeit clearly remaining subthreshold in many benchmarks. Probably a matter of time and/or dedicated (rogue) training efforts...
Claude 4 system card:
www-cdn.anthropic.com/6be99a52cb68...
We quantify the aggregation of >100,000 random protein sequences to train CANYA, a convolution-attention hybrid neural network to predict aggregation from sequence. With @bennibolo.bsky.socialwww.science.org/doi/10.1126/...
Many of the moons orbiting Jupiter and Saturn appear to host subsurface oceans. Mysteries abound as to what fills these deep sea worlds. But the hints that we’ve already gathered make them tantalizing targets in the search for life beyond Earth.
🧵
Sad news. Benny Shilo, a pioneer in dev bio & Drosophila genetics, has died.
I'll remember the infectious enthusiasm and burning curiosity he brought to every conversation I had with him.
On the anniversary of the sinking of the Titanic, we thought we'd answer a question that's often asked,
"If they raised the Mary Rose, why not raise the Titanic?"
Allow our scaled diagram to explain...
We then used a physics-based model to predict DNA linkers between the nucleosomes obtained by cryo-ET. This allowed us to visualize kbp-long chromatin fragments from inside human cells.
This really is remarkable finding - receiving the herpies zoster vaccine reduced the probability of a new dementia diagnosis over a follow-up period of 7 years by 3.5 %, corresponding to a 20.0% relative reduction; protective effect stronger in women > men
🧪 #MedSkywww.nature.com/articles/s41...
23andMe has filed for bankruptcy and legal permission to auction off its assets - could this cloud have a silver lining for researchers? A new owner of the impressive dataset could make it more accessible to researchers… 🤞🏼
🧪
www.nature.com/articles/d41...
A Review in Nature Reviews Biodiversity summarizes how differing forest restoration approaches affect impacts on biodiversity, and key knowledge gaps and research priorities for achieving biodiversity-centred restoration. https://go.nature.com/4c0XIuh 🧪
Join our favorite microbiology meeting! Fantastic talks, poster sessions, new technologies, and all the hot areas of microbiology in a great environment - experts in cell & systems biology, microbiomes, environment & evolution, pathogenesis, phage & antibiotics
DON’T MISS abstract deadline, April 1
Why is an AI agent not doing your job already?
Apparently it’s because they struggle to keep track of multiple streams of information, respond to a dynamic environment, work with unclear or changing goals & multitask….
Looks like quite a few jobs are safe for now 😉
on.ft.com/4iEMIoK
Gearing up mRNA vaccines ("tolerogenic") to prevent autoimmune diseases, vital science that is currently under irrational and reckless attack
www.nature.com/articles/s41...
A huge loss at FDA.
Peter Marks originated rhe Operation Warp Speed Covid vaccine idea and has overseen so many essential biotech programs such as genome editing cures www.wsj.com/politics/top...
The unparalleled XJ Wang has written a book about the computations underlying cognition. I read a draft version and it is awesome. He is not on social media, so I am sharing it on his behalf :)
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
My OpEd in @elife.bsky.social
“It feels as if we are trying to fight a series of attacks on science with one arm tied behind our back and our lips half sewn shut.”
“Yet we are not beaten, and some of us are downright energized.”
elifesciences.org/articles/106...