The Longevity Initiative

Hi! We are The Longevity Initiative, a new think tank and educational organisation working towards a world free from age-related disease, where longevity medicines are accessible to everyone. Find out more at our website, thelongevityinitiative.org 🐢

Great to see the launch of AD-SMART, a multi-arm platform trial to test new drugs for Alzheimer’s in the UK’s NHS. We would love to see something similar for repurposed longevity medicines—which might even be some of the same drugs!

Could a longevity breakthrough cause a pensions crisis? Check out the new post from @thelongevityinitiative.org:

Our Director Andrew Steele (@statto.bsky.social) was interviewed for BBC Radio 4’s Rethink, on the difference between chronological and biological age, and the first treatments aiming to close it. Listen here:

We spoke with Social Capital for their new Deep Dive on longevity! Ageing is the biggest shared risk factor for the diseases that kill us, but they find that it gets just 0.25% of global biomedical R&D. Read more here:

We’ve been on there for a while, but just officially launched on @linkedin.com! Check out our article on what we started a think tank, not a biotech – and please give us a follow over there and share our page with your network.

Lovely to see a spike in traffic for our 2025 longevity business round-up last week as the Retro Bio news broke! If you're catching up on the reprogramming gold rush, the biotech funding drought and recent big exits, it’s all here:

Does NIH research funding track what actually kills Americans? Building on A4LI’s new report, we ran the numbers: and ageing fares worst. Ageing causes 83% of deaths, yet receives just 1.2% of the research funding per death that cancer does—around $1 per American per year.

New post: Can longevity save us from a population crisis? We tried out @ourworldindata.org’s new population projection tool to see if increasing life expectancy could save us from demographic decline:

New post: Can longevity save us from a population crisis? We tried out @ourworldindata.org’s new population projection tool to see if increasing life expectancy could save us from demographic decline:

The Human Ageing Genomic Resources are vital open-source databases on longevity genes and drugs, and animal lifespans. It would be a loss to the field if they go offline due to funding cuts. See @jpsenescence.bsky.social’s post here for more details and how to support:

Why does the word ‘longevity’ seem to be everywhere at the moment? The final piece in our round-up of the last year in longevity looks at how ageing, wellness and biohacking cropped up in the media, pop culture and…in discussions between Putin and Xi? Please enjoy this Friday read:

Longevity clinics grow in popularity while biohackers are hospitalised by peptide injections—and does Ozempic slow the ageing process? We take a look at the last year in longevity medicine:

US ageing research funding could drop from $1.04 to 62 cents per person. Europe spends even less. Meanwhile, @xprize.org Healthspan's $101 million competition announces semifinalists. Part 3 of our year in review:

Billion-dollar bets on cellular reprogramming, biotech's rough year, and early FDA success for healthy lifespan extension in dogs. The biggest business news in longevity in the last year:

To kick off 2026, we’re publishing a week of articles looking back at 2025 in longevity. The first is 2025 in longevity science—two new drug cocktails make mice live longer, plus clocks to measure the age of your organs and ‘extracellular vesicles’ improve signs of ageing in monkeys. Read it here:

The majority of poor health and deaths globally are caused by diseases that become common with age. But public policy has yet to catch up with ageing science, and longevity research is underappreciated, and underfunded. We exist to change that. Support us here:

My friend Andrew Steele is building this: The majority of poor health and deaths globally are caused by diseases that become common with age... "But public policy has yet to catch up.. & longevity science is underappreciated, and underfunded We exist to change that" 🧑‍⚕️⚕️ thelongevityinitiative.org

The future of health depends on better longevity science. That depends on more regular people and politicians knowing what longevity *is*. Thanks to collaboration with Vitalism Charitable Foundation, US donors can support The LI tax-efficiently. Donate before year-end 👉

We’re fundraising! And, just in time for the end of the tax year, we’ve partnered with Vitalism Charitable Foundation 501(c)(3) to enable US taxpayers to make a donation intended to support The Longevity Initiative which may be tax-deductible. Find out more here:

Just in time for Christmas, here are my top 3 tips for a healthier 2026! Watch this, and more details in the thread below…