Agingdoc⭐David Barzilai🔔MD PhD, MS, MBA, DipABLM

I'm honored to join Harvard Medical School as a part-time Lecturer. If you're a colleague at @harvardmed.bsky.social working on upcoming conferences or educational initiatives across healthspan I’d welcome the opportunity to collaborate.👨‍⚕️ Please reach out at 🔗https://www.linkedin.com/in/agingdoc/

“Can We Reverse Aging?” is our episode title. My answer: not with today’s science. I joined @DarshanShah_MD to explore whether we can slow aging and extend healthy lifespan. I hope you’ll watch the full conversation. Thanks for your support! youtu.be/P5053hkoXU8

Earlier detection of health risks matters when it leads to better outcomes. I discussed this on Kastljós, Iceland’s national broadcaster, and shared my thoughts on how evidence-based longevity medicine can improve preventive care. Read more on LinkedIn: lnkd.in/p/gV8Tfizb

What Actually Slows Aging? The Science vs. Hype | Dr. David Barzilai Dr. Kara Fitzgerald with @agingdoc.bsky.social youtu.be/3wngpV7jyAI

We are searching for a physician-scientist to be the medical director for a new Center for Healthy Aging at OMRF. This is a unique opportunity to bridge existing strengths in the basic biology of aging with precision geromedicine.

Excited to announce the Translational Longevity Summit, Oct 7-11 💫 Five days where frontier geroscience meets real clinical practice ⚕️ Produced by with Boston BioLife, the Healthspan Action Coalition, and the World Stem Cell Summit. 🚀 🔗 healthspanaction.org/translationa...

Longevity is advancing quickly, but promising ideas must be separated from meaningful evidence. I enjoyed speaking with Atanas about biological age, geroprotectors, AI, and healthy aging. inpst.net/pathways-to-...

It’s here🌟 I served as Medical Editor for this 50-page report, to bring rigorous, evidence-based longevity science to a broad general audience. Grateful to have contributed, excited to see the longevity conversation move further into the mainstream. Please share👇 www.linkedin.com/feed/update/...

How We Should Target Aging | Peter Fedichev www.youtube.com/watch?v=buEP...

GENE THERAPY SAFELY ERADICATES BRAIN TUMOURS IN MICE A single dose of an innovative gene therapy could eliminate hard-to-treat brain tumours and prevent them from coming back, according to a pre-clinical trial in mice, reported in Nature. edinburgh-innovations.ed.ac.uk/news/trogeni...

Dead End': Radical 20-Year Study Reveals Genetic Cloning Hits a Limit www.sciencealert.com/dead-end-rad...

Geroscience’s Guiding Star: Extending Healthy Lifespan 🌟"Barzilai makes a clarion call for a “moonshot”-level investment in aging biology... This ambitious commitment aims to accelerate the field’s capacity [to] extend both lifespan and healthspan" worldwide. 🌍 🚀 bioengineer.org/gerosciences...

Patients are asking for time with family, time in full cognition, time in independence, and time living on their own terms. That is why geroscience should be judged not only by survival, but by whether it extends life by extending health. My Editorial: www.linkedin.com/posts/agingd...

My Editorial 🩺 "...stop treating “lifespan vs. healthspan” as a fork in the road. In medicine, and in the lives our patients actually live, they are not competitors. The only mission that is both scientifically coherent and clinically meaningful is healthy life extension: more years in full health"

Gut microbes affect cognition during ageing As mice age, changes in the microorganisms in their guts contribute to cognitive decline by altering signalling between the gut and brain. www.nature.com/articles/d41...

Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice onlinelibrary.wiley.com/doi/10.1111/...

Impact of exercise-induced DNA damage repair on age-related muscle weakness and sarcopenia 👉 “exercise-induced enhancement of DNA repair [contributes to] maintaining mitochondrial health, preserving muscle stem cell function, and combating cellular senescence” www.frontiersin.org/journals/gen...

Is #geroscience and #longevity for everyone, or just for a few? Podcast on the ethics of it all, with @agingdoc.bsky.social and Carolyn Ringel: www.youtube.com/watch?v=Tedu...

Boston’s Longevity Obsession: What Works and What’s Expensive BS We're becoming more & more obsessed with living forever—but not all the treatments are created equal. What works, what doesn’t and whether optimizing every aspect of your life is really worth it. www.bostonmagazine.com/news/2026/01...

How to Make Friends as an Adult A practical guide for expanding your circle, with advice from sociable people. www.nytimes.com/article/how-... @nytstyle.bsky.social

Glucagon-like peptide-1 medicines and cancer www.nature.com/articles/s43...

Senate advances bills rejecting Trump’s efforts to slash research funding 🧪 The White House requested cuts of 40% or more at some agencies. But lawmakers from both parties are pushing to hold science spending relatively steady. www.highereddive.com/news/senate-...

Irradiated cannabis might still harbour toxic fungi and residues, McGill study finds Researchers raise concerns about possible health risks for vulnerable users, point to a need for better methods and safeguards www.mcgill.ca/newsroom/cha...

Targeted delivery of genome editors in vivo 🧬"Targeted delivery promises to considerably expand the therapeutic applicability of genome editing, moving closer to the ideal of a precise ‘magic bullet’ that safely and effectively treats diverse genetic disorders." 🩺 www.nature.com/articles/s41...

My friend Andrew Steele is building this: The majority of poor health and deaths globally are caused by diseases that become common with age... "But public policy has yet to catch up.. & longevity science is underappreciated, and underfunded We exist to change that" 🧑‍⚕️⚕️ thelongevityinitiative.org

This company is developing gene therapies for muscle growth, erectile dysfunction, and “radical longevity” 💉 A small group of volunteers will receive multiple injections of the experimental treatments next month, says Unlimited Bio 👨🏻‍⚕️ t.co/hMdyfVk58W

Interrupting Prolonged Sitting Reduces Postprandial Glucose Concentration in Young Men With Central Obesity 👉 Interrupted prolonged sitting [3 min light walking or 1.5 minutes of moderate walking every 30 minutes] reduced postprandial glucose concentrations. academic.oup.com/jcem/article...

People often ask me the same question: “What’s the single most promising anti-aging measure coming in the next decade?” If you care about where longevity medicine is truly heading, this one’s worth a look. 🔗https://www.instagram.com/reel/DRni2qQgNTS

Semaglutide versus caloric restriction-induced weight loss: insights into effects on skeletal muscle mass and function "[suggests] loss of muscle function and mass during treatment is not unique to GLP-1RA pharmacology but rather reflects the biology of caloric restriction…" x.com/agingdoc1/st...

My post from Founders Forum North America (NYC) 🗽 🔗 www.linkedin.com/posts/agingd... 🚀

AI Learns to Design the Human Body’s Most Elusive Proteins 🤩 Summary: A new machine learning method has achieved what even AlphaFold cannot… their ever-changing structures have defied traditional AI prediction models. neurosciencenews.com/ai-protein-d...

Scientists make embryos from human skin DNA for first time www.bbc.com/news/article...

This AI tool predicts your risk of 1,000 diseases — by looking at your medical records Trained on 400,000 medical records, the system can predict risks 20 years in advance — plus, how AIs could make you more likely to cheat nature.com/articles/d41... @shamini.bsky.social 🧪

Sex-specific longitudinal reversal of aging in old frail mice www.aging-us.com/article/2063...

The evolution of cancer and ageing: a history of constraint www.nature.com/articles/s41...

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Fraudulent Scientific Papers Are Rapidly Increasing, Study Finds A statistical analysis found that the number of fake journal articles being churned out by “paper mills” is doubling every year and a half. 🤯 www.nytimes.com/2025/08/04/s...

Healthy Lifestyle Can Help People at Risk for Dementia, Study Finds The study found that a combination of exercise, healthy diet and other behaviors led to cognitive benefits… www.nytimes.com/2025/07/28/h...

DNA Methylation Ageing Atlas Across 17 Human Tissues 👉“Our open-access atlas provides a foundational resource for dissecting the molecular architecture of human aging and identifying testable targets for intervention..” @nireynon.bsky.social and coauthors www.biorxiv.org/content/10.1...

Editorial: Resilience in aging @drlaurahaynes.bsky.social and coauthors www.frontiersin.org/journals/agi...

AlphaGo Moment for Model Architecture Discovery 👉“ASI-Arch is presented, the first demonstration of Artificial Superintelligence for AI research (ASI4AI) in the critical domain of neural architecture discovery, with the first empirical scaling law for scientific discovery itself..“ t.co/ljJ1fXsslE

Fearful of AI-generated grant proposals, NIH limits scientists to six applications per year Some critics of the new policy say the cap could hinder researchers in need of funding www.science.org/content/arti...

'They hold hands, they embrace, they kiss': The woman who changed our view of chimps - and human beings www.bbc.com/culture/arti...

Just How Harmful Is Vaping? More Evidence Is Emerging. A new study that found high levels of heavy metals in popular nicotine vapes adds to concerns about the products. www.nytimes.com/2025/07/09/w...

Alpha males are the exception, not the rule, bold new study claims Clear-cut male dominance is surprisingly rare in our animal relatives – and many females hold more sway than expected www.sciencefocus.com/news/alpha-m...

How to burn more fat while exercising Lifting weights before cardio can enhance benefits but it’s not the only way to get more bang for your buck. Here’s what experts recommend www.thetimes.com/life-style/h...

Misleading Conclusions Die Hard: Citing Flawed Research for Personal Agendas journals.lww.com/acsm-csmr/ci...

How many PhDs does the world need? Doctoral graduates vastly outnumber jobs in academia PhD programmes need to better prepare students for careers outside universities, researchers warn. www.nature.com/articles/d41...

Doctors Told Him He Was Going to Die. Then A.I. Saved His Life. Scientists are using machine learning to find new treatments among thousands of old medicines. www.nytimes.com/2025/03/20/w...