Kinga Kamieniarz-Gdula

Kinga Kamieniarz-Gdula

@stoplab.bsky.social

Molecular biologists fascinated by gene ends. PI at IBMiB and CAT, Adam Mickiewicz University in Poznan, Poland. Oxford University and @mpi_ie Freiburg alumna. STOPlab.org

1.6K followers1.1K following115 posts

Kinga Kamieniarz-Gdula reposted

We find numerous examples like this -- people present in a crowd being violently treated by police as if they are rioters -- in our research on cases where peaceful crowds become violent and conflict escalates. www.theguardian.com/world/2026/o...

theguardian.com‘An orchestra being gassed should be an alarm signal’: the musical activists targeted in ParisNew World Orchestra’s musicians are shocked at French police targeting peaceful gathering with teargas

Kinga Kamieniarz-Gdula reposted

Our latest paper is out in @embojournal.org! Chromatin compaction is a hallmark of apoptosis, but the mechanism & function of this process was unclear. We show apoptotic compaction is required to prevent fragmented DNA from spreading beyond the dying cell, and is driven by histone deacetylation.

The EMBO Journal@embojournal.org

How does DNA remain confined to dying cells despite its fragmentation? @mfdspicer.bsky.social @rcollepardo.bsky.social @gerlichlab.bsky.social et al show histone deacetylation compacts apoptotic chromatin, preventing it from entering apoptotic extracellular vesicles link.springer.com/article/10.1...

Kinga Kamieniarz-Gdula reposted

Kinga Kamieniarz-Gdula reposted

Very nice discovery from the Jackson, Bravo and Basel labs. Cleaved tRNA ends, loaded with an amino acid, activate a form of bacterial immunity

bioRxiv Microbiology@biorxiv-microbiol.bsky.social

Aminoacylated tRNA tails trigger auxiliary bacterial immunity https://www.biorxiv.org/content/10.64898/2026.10.14.759216v1

See below for a cancer biology-oriented view on our new paper by co-first author & bioinformatician Deepshika Pulimamidi 👇

dpulimamidi.bsky.social@dpulimamidi.bsky.social

Primary and metastatic colorectal tumor cells share a common origin, but do they share the same molecular vulnerabilities? Surprisingly, primary cells depend far more on #PCF11 and #CPSF73, two key pre-mRNA 3' end processing/termination factors. Our latest study explores why: tinyurl.com/3pkeuctp

Kinga Kamieniarz-Gdula reposted

Kinga Kamieniarz-Gdula reposted

Kinga Kamieniarz-Gdula reposted

Kinga Kamieniarz-Gdula reposted

Our cover design for Molecular Cell did not get selected this time, but I still wanted to share the artwork celebrating our latest paper identifying an unexpected role for ZC3H18 in cap-dependent first intron splicing article: doi.org/10.1016/j.mo...

Kinga Kamieniarz-Gdula reposted

Development is happy to be a @reviewcommons.org affiliate journal, aiming to reduce reviewer burden and speed up publishing for authors. Read the articles we've published via Review Commons here: journals.biologists.com/dev/collecti... And find out more about the platform:

EMBO@embo.org

We spoke with four researchers who have repeatedly chosen Review Commons as a preprint #PeerReview platform for their own work. 🧪 Learn why they decided on Review Commons here: https://www.embo.org/features/why-i-chose-review-commons/ #LifeSciences #research #publishing #preprint

Kinga Kamieniarz-Gdula reposted

EMBO brought its communities together at the annual EMBO Fellows’ and Members’ Meeting from 26–30 September and 30 September–2 October, respectively. More here: https://www.embo.org/features/two-meetings-one-community-how-embo-celebrates-life-sciences/ 🧪 #LifeSciences #community #networking

embo.orgTwo meetings, one community: How EMBO celebrates life sciences  – Features – EMBOThe EMBO annual Fellows’ and Members’ Meetings 2026 made room for creativity and storytelling in science

Kinga Kamieniarz-Gdula reposted

Two steps in gene expression that should move together… don’t. In our new paper we show that pre-mRNA cleavage and RNA polymerase II (RNAPII) termination shift in opposite directions – with a surprising link to gene expression and cancer cell vulnerability. Read more here: tinyurl.com/3pkeuctp

#RNABiology #MolecularBiology #GeneExpression #RNASky

Agata Stepien@agatakstepien.bsky.social

Two steps in gene expression that should move together… don’t. In our new paper we show that pre-mRNA cleavage and RNA polymerase II (RNAPII) termination shift in opposite directions – with a surprising link to gene expression and cancer cell vulnerability. Read more here: tinyurl.com/3pkeuctp

Very proud of this study! Two fundamental processes in gene expression turn out less tightly connected than thought. And their relationship may help explain some surprising vulnerabilities of cancer cells. A big thank you to Agata and Deepshika for years of hard work, and kudos to all collaborators!

Agata Stepien@agatakstepien.bsky.social

Two steps in gene expression that should move together… don’t. In our new paper we show that pre-mRNA cleavage and RNA polymerase II (RNAPII) termination shift in opposite directions – with a surprising link to gene expression and cancer cell vulnerability. Read more here: tinyurl.com/3pkeuctp

I only used Review Commons once so far, but had a great experience!

EMBO@embo.org

We spoke with four researchers who have repeatedly chosen Review Commons as a preprint #PeerReview platform for their own work. 🧪 Learn why they decided on Review Commons here: https://www.embo.org/features/why-i-chose-review-commons/ #LifeSciences #research #publishing #preprint

Kinga Kamieniarz-Gdula reposted

Kinga Kamieniarz-Gdula reposted

Kinga Kamieniarz-Gdula reposted

There is still time to apply for the EMBL International PhD Programme! 📢 Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research. Research groups across EMBL are recruiting now! bit.ly/4x9Edss

Kinga Kamieniarz-Gdula reposted

Your regular reminder: If the Russians stop fighting, the war ends. If the Ukrainians stop fighting, their land will be occupied, their leaders will be killed, their history and language will be erased, their children will be kidnapped to serve Russia.

Kinga Kamieniarz-Gdula reposted

‼️🚨Out now in Molecular Cell - Our latest study 𝐫𝐞𝐯𝐞𝐚𝐥𝐢𝐧𝐠 𝐧𝐞𝐰 𝐢𝐧𝐬𝐢𝐠𝐡𝐭𝐬 𝐢𝐧𝐭𝐨 𝐅𝐀𝐂𝐓 𝐟𝐮𝐧𝐜𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐭𝐡𝐞 𝐢𝐦𝐩𝐨𝐫𝐭𝐚𝐧𝐜𝐞 𝐨𝐟 𝐧𝐮𝐜𝐥𝐞𝐨𝐬𝐨𝐦𝐞 𝐨𝐫𝐠𝐚𝐧𝐢𝐬𝐚𝐭𝐢𝐨𝐧 𝐟𝐨𝐫 𝟑𝐝 𝐠𝐞𝐧𝐨𝐦𝐞 𝐦𝐚𝐢𝐧𝐭𝐞𝐧𝐚𝐧𝐜𝐞: tinyurl.com/2xctvx38. It was a pleasure to lead this collaborative effort alongside @nilskrietenstein.bsky.social More in🧵below 🪡

tinyurl.comMaintenance of nucleosome organization through replication and transcription counteracts aberrant coalescence of active chromatinNucleosomes with their associated modifications organize and regulate the genome. It is unclear how this is integrated with the requirement of replica…

Kinga Kamieniarz-Gdula reposted

Kinga Kamieniarz-Gdula reposted

Join us at the "Cancer Research Across Scales" conference at the Weizmann Institute of Science! Many Israelis living abroad may be in Israel that week for the national election, so help us spread the word!

Kinga Kamieniarz-Gdula reposted

DNA G-quadruplexes are dynamic four-stranded #DNA knots that may control genes, protect genomes, and drive disease, yet are poorly understood. This Unsolved Mystery by Irene Gallina & Sara Richter investigates their origins and functions. 🧪 #AcademicSky plos.io/4aXJXNC

Kinga Kamieniarz-Gdula reposted

Kinga Kamieniarz-Gdula reposted

Really appreciate @agatakstepien.bsky.social and Kinga @stoplab.bsky.social for surprising us with this kind shout out to our work! I love how they pull together these important pieces of an emerging puzzle!

Agata Stepien@agatakstepien.bsky.social

Studying gene ends is becoming even more fascinating! Curious why? Read our News & Views "Transcriptional readthrough progresses from incidental byproduct to therapeutic opportunity" inspired by the recent publication by Podszywałow-Bartnicka and @karlaneugebauer.bsky.social @natsmb.nature.com

Kinga Kamieniarz-Gdula reposted

There is more to transcriptional readthrough than meets the eye, and it could even provide a therapeutic opportunity in cancer. Check out our new perspective, inspired by recent work from Neugebauer and Grzechnik labs! #RNABiology #RNASky #Epigenetics

Agata Stepien@agatakstepien.bsky.social

Studying gene ends is becoming even more fascinating! Curious why? Read our News & Views "Transcriptional readthrough progresses from incidental byproduct to therapeutic opportunity" inspired by the recent publication by Podszywałow-Bartnicka and @karlaneugebauer.bsky.social @natsmb.nature.com

Kinga Kamieniarz-Gdula reposted

“Killer” is too kind. Musk is a mass murderer. He’s disrupting democracies around the world. Not to mention the “mechahitler” white-supremacist misogyny machine of Grok & X. I witnessed firsthand the cruel, ignorant, wasteful destruction at NASA at the hands of DOGE. www.theverge.com/tech/949259/...

theverge.comThe world’s first trillionaire is a killerElon Musk’s empire of wealth is built on suffering.