Reena Kumari

Handmade postcard for a cell migration enthusiast. #cellart #scienceart

Check out our new paper in JCB today all about septins!

In @jcb.org, @maggieutgaard.bsky.social, @myosincity.bsky.social, @pwoakes.bsky.social et al. show that #septins accumulate at the cortex in response to mechanical cues, where they serve to buffer mechanical forces that act on the #nucleus. rupress.org/jcb/article/... #Cytoskeleton #Mechanobiology

From MBoC: How do cells coordinate actin and microtubules? New research shows that CAP-driven actin turnover helps organize microtubules in epithelial cells, supporting trafficking and cell architecture. https://www.molbiolcell.org/doi/10.1091/mbc.E26-07-0321

The first paper of my PostDoc in Christa Schlepers group (@archaea-vienna.bsky.social) on the dynamics of Asgard archaea is now out in Nature! www.nature.com/articles/s41... This was a great team effort and I am looking forward to uncover the complex behavior of these cells further!

I think I'm going to lose it being lectured on microscopy image presentation integrity by the winner of the Small Artificial World in Motion competition

Excited to share that our latest story on #microtubule conformation controlling cell #signaling is now out in NCB! We show that microtubule expansion by taxane chemotherapeutics releases microtubule bound GEF-H1 which in turn activates RhoA/ROCK signaling. ✨ www.nature.com/articles/s41...

In a new preprint we provide evidence that biophysical properties of protein condensates can explain the order of events in the endocytic pathway, and that these events are tuned by protein condensate phosphorylation. www.biorxiv.org/content/10.6...

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/

I have an open position for a PhD student. In my newly established lab @helsinki.fi we investigate regenerative processes in the mammalian liver. The call is open until October 6th. Apply here: tinyurl.com/mh9k2nav For more information: www.pentinmikko-lab.com Please share!

Very interesting paper. An old-fashioned concept - sadly now rare in biology - measure stuff accurately, and you can understand how it works... www.biorxiv.org/content/10.6...

www.biorxiv.org/content/10.6... DAAM1 formin and Ena/VASP proteins assemble functionally distinct actin filaments for focal adhesions

Check this interesting work from the amazing @xianglejerry.bsky.social from Lappalainen Lab

super awesome postdoc opportunity alert!

#fluorescenceMonday Love the veils of dendritic cell under partial confinement. #actin

1/5 🎉 Finally, the results of my main postdoctoral project are out in @natcomms.nature.com! Adhesion-derived condensates control component availability to regulate adhesion dynamics bit.ly/4y9E8Xr Also excited to see the paper highlighted in Nat Comms Editors’ Highlights 🥳 bit.ly/44n4O9i

Inspiration often arrives when we least expect it. For ISTA scientist @reenak.bsky.social​, it sparked while she and her colleagues captured actin filaments under the microscope. The result is not only a beautiful art piece but also a glimpse into the cellular architecture that shapes life.

🚨 PhD Position Available 🚨 I’m recruiting a PhD student to join my lab at the Multiscale Imaging Centre (MIC), Münster, Germany. www.bischofflab.com/jobs Fully funded ✅ #Cellbio #Morphogenesis #Microscopy #Drosophila #PhD (Details Below) Original Posting: stellen.uni-muenster.de/jobposting/d...

We are very happy to share our latest work exploring the role of newly synthetized integrin-α5 using RUSH. We found that a subset goes to the PM via unconventional secretion! Big thanks to all involved! Read more at doi.org/10.1083/jcb.... @mathildemathieu.bsky.social @martina-lerche.bsky.social

Lerche, Mathieu, @johannaivaska.bsky.social @ivaskalab.bsky.social et al. reveal that newly synthesized #integrins can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance cell protrusion and #adhesion. rupress.org/jcb/article/...

Interested in cell migration yet bored of the canonical translocation modes? 😴 Don’t worry — we @nordenlab.bsky.social with @aiopticalbiolab.bsky.social have multipolar migration back in stock! No need to follow the other cells: extend long protrusions and roam more freely🪼 in the crowded brain.

- A postdoc to work on cancer extravasation (4-year project). - A postdoc help in completing Filopodia-related lab projects (2-year). - Multiple Marie Curie postdoc positions that will open in the fall. - We will open a 5-year position to cover my teaching (70% research and 30% teaching).

I'm grateful for the Research Council of Finland for granting me the Academy Research fellowship! After getting over the shock I will soon move back to Finland to start as a group leader at the Institute of Biotechnology @helsinki.fi. Looking for a PhD student soon! www.aka.fi/en/about-us/...

Hot from the press for #CellMigration + #Nucleus aficionados Karling @helenweavers.bsky.social lab show *in vivo* how immune cell adapt quickly to confined microenvironments during motility. Live-cell imaging, image analysis, #Drosophila ! Full @emboreports.org www.embopress.org/doi/full/10....

Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology www.biorxiv.org/content/10.1...

Some microscopy reading 🔬📰 Single-molecule orientation-localization microscopy: Applications and approaches www.cambridge.org/core/journal...

#fluorescencefriday #macrophages on nano-ridges stained for actin. Imaged with Zeiss Elyra 7 #actin #cytoskeleton #microscopy #cellbiology

Mix two motors of opposite polarity with microtubules and they will partition space ! Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns. #morphogenesis doi.org/10.1073/pnas... (1/n)

Introductory post on 🦋! We're a research group headed by Prof. Johanna Ivaska interested in understanding how integrins contribute to every step of cancer progression. We're located at the Turku Bioscience Center in Turku, Finland! Find out more about us and our interests here: ivaskalab.utu.fi

Extracellular matrix-dependent regulation of Septin 7 in focal adhesions promotes mechanosensing and functional response in fibroblasts www.sciencedirect.com/science/arti...

In the aftermath of last weeks disaster I exited social media for a week. Today I came back here to find to my delight that the reassembly of science twitter has dramatically accelerated. Welcome/hello to the nearly 500 people who followed me in the last 6 days-we can make this a place for science!!