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Qihong (Q) Lu
Qihong (Q) Lu
@qlu.bsky.social
Computational models of learning and memory Assistant Professor in Neuroscience @ CityU Hong Kong Postdoc with Daphna Shohamy & Stefano Fusi @ Columbia PhD with Ken Norman & Uri Hasson @ Princeton https://qlulab.github.io/website/
1.4K followers669 following65 posts
Qihong (Q) Lu reposted
Medial PFC interacts with the hippocampus to retrieve context-congruent memories.. but HOW?? was what started this. Simulating mPFC-HIP🧠, we designed an RNN🤖 that retrieves memories similar in context, on top of self-attention. It learns to retrieve like humans faster! arxiv.org/abs/2609.37791
Qihong (Q) Lu reposted
What kind of dynamics underlie sequence working memory? In the last project of my PhD we developed and analysed RNNs fitted to multi-session single-unit data of macaques. Now out on: www.biorxiv.org/content/10.6... With @jakhmack.bsky.social and data from Chen et al., Neuron 2024. [1/4]
Qihong (Q) Lu reposted
New lab preprint! @khoudary.bsky.social presents a tour-de-force: a new model of how uncertain expectations should help resolve uncertain sensations, supported by re-analysis of four experiments in monkeys (behavior, ephys) and humans (behavior, fMRI, EEG, intracranial) @meganakpeters.bsky.social
how does memory support perceptual decisions made under uncertainty? this question has scaffolded my entire PhD, and I'm so excited to share part of it in this ✨new preprint ✨ w/ @meganakpeters.bsky.social and @aaronbornstein.bsky.social! link: www.biorxiv.org/content/10.6...
Qihong (Q) Lu reposted
Sometimes we know an experience is important in the moment. Other times, its importance only becomes clear after the fact. Do these two cases have different consequences for memory? In our new paper we found that both kinds of prioritization impact memory in different ways! doi.org/10.1162/OPMI...
Qihong (Q) Lu reposted
Our task-switching paper is now out at Current Biology! www.cell.com/current-biol... We find that that our brains reset to a task-neutral state between trials, providing flexibility when the upcoming task is uncertain. RNNs also learn this strategy, but only when trained to switch tasks.
Qihong (Q) Lu reposted
The Naturalistic Cognitive Computational Neuroscience Lab is launching at UT Austin and is looking for founding members at all levels, including lab manager, PhD students, and postdocs! #NeuroJobs We will study human brain🧠 and memory & attention, using fMRI and modeling. thesonglab.github.io
Qihong (Q) Lu reposted
42 new #fmri tutorials to accompany our new book Elements of fMRI, with @fMRIstats. Run code in both #python and #matlab in your browser to explore. 7 sections, from conceptual foundations to machine learning and AI. torwager.github.io/elements-of-...
Qihong (Q) Lu reposted
In a recent PNAS Profile, we explore Morris Moscovitch’s influential work on how the brain stores and retrieves memories. His research reshaped our understanding of the hippocampus and revealed its role in memory. Read more: https://ow.ly/mMrQ50ZxFZ1
Qihong (Q) Lu reposted
Replying to @lorenzoposani.com
Fin/ check out the paper at www.nature.com/articles/s41...! Huge thanks to Pia O'Neill (new assistant prof at Dartmouth sites.dartmouth.edu/oneill-lab/) for leading this project, and to @stefanofusi.bsky.social & Daniel Salzman for the fantastic collaboration! Cover artwork matteofarinella.com/
Qihong (Q) Lu reposted
Excited to share that my first-ever first-author paper (w/ @atabk.bsky.social @AngeliqueDelarazan @zreagh.bsky.social) is now out in PNAS! Building a story to link two objects boosts associative memory and inference, but not memory for the objects themselves. www.pnas.org/doi/10.1073/... 🧵
Qihong (Q) Lu reposted
Can MEG provide a non-invasive window onto human ripple physiology during sleep? Our new preprint suggests it can. Led by the fantastic @fabian31415.bsky.social. Many thanks to our collaborators @olejensen.bsky.social , @doellerlab.bsky.social , and @tobiasstaudigl.bsky.social #Neuroskyence
Can we study MTL ripples non-invasively? New preprint! We show that source-resolved MEG tracks ripple-like activity during sleep that: • localizes to the MTL • follows the canonical SO–spindle hierarchy • matches an iEEG benchmark • indexes memory reactivation www.biorxiv.org/content/10.6...
Qihong (Q) Lu reposted
This is a really interesting and important study: www.nature.com/articles/s41... However, isn't it concerning that sweeping conclusions about functional organization of cortex are being reached on the basis of a single task?
Qihong (Q) Lu reposted
Thanks to Kshipra Guranandan, my notebook on how to design efficient fMRI experiments (for activity, connectivity and pattern analysis) is now available in Python as a Jupyter notebook (as well as previous Matlab): github.com/RikHenson/fM...
Memory palace like strategy can naturally emerge in an RNN trained to do the free recall task! Very honored to be involved in this work. Congrats again @moufanli.bsky.social :)
Our paper is out in @natmachintell.nature.com! We trained multiple RNNs to perform free recall. The best-performing ones learned a strategy akin to the memory palace technique. See thread below for more info. www.nature.com/articles/s42...
Qihong (Q) Lu reposted
New preprint from the lab! “A number simplex in the human medial temporal lobe” led by @hanlin-zhu.bsky.social 🧵 www.biorxiv.org/content/10.6...
Qihong (Q) Lu reposted
From a great collaboration with @lorenzoposani.com, @shuqiw.bsky.social, Samuel Muscinelli, Liam Paninski, now in Nature: www.nature.com/articles/s41...
Qihong (Q) Lu reposted
Hippocampal engrams configure prefrontal context representations to guide flexible decisions Impressive combo of methods to manipulate and record this process: www.biorxiv.org/content/10.6...
Qihong (Q) Lu reposted
Provocative title ftw. (Tho it inspired @kristorpjensen.bsky.social to give a talk titled "planning in the brain: it's not what nathaniel thinks it is")
The 2026 volume of the Annual Review of Neuroscience is now online 🧠 The most read article is "Planning in the Brain: It's Not What You Think It Is" by @marcelomattar.bsky.social and @nathanieldaw.bsky.social
Qihong (Q) Lu reposted
Our paper "Neural timescales from a computational perspective" is finally out in @natneuro.nature.com: www.nature.com/articles/s41... We discuss how computational models and methods can distill empirical observations on neural timescales into quantitative, testable theories of brain computation.
Qihong (Q) Lu reposted
We're finally getting the tools to study replay in humans. But why bother? What can we learn from it that we don't know from rodent recordings? Our thoughts are now out in a new TICS Forum Great fun writing this w @smfleming.bsky.social + @maritpetzka.bsky.social authors.elsevier.com/sd/article/S...
Qihong (Q) Lu reposted
I am so excited about this finding from @pengrui-han.bsky.social and @andreadevarda.bsky.social, also with Jacob Andreas! Perhaps modularity is inevitable in intelligent systems, biological or in silico. :)
The human brain is strikingly modular: distinct networks for language, formal reasoning, social reasoning, physical reasoning. Is this fundamental to intelligent systems, or an accident of evolution? In our new preprint, we find the same modular organization emerges in LLMs.
Qihong (Q) Lu reposted
🧠 New preprint! How well can current algorithms *actually* detect neural "replay" in the human brain under absolutely optimal conditions? We built FASTIMAGES: A combined MEG + fMRI benchmark with KNOWN neural sequences, so replay-detection methods can finally be validated against a ground truth.
Qihong (Q) Lu reposted
Our new paper is out this week in Nature Neuroscience! www.nature.com/articles/s41... We built a BCI that works with the brain's natural geometry — and we found that people could learn to play a video game with their brains in <1 hr of training. This efficiency is groundbreaking & here's why:
Qihong (Q) Lu reposted
"Prior knowledge biases episodic memory by filling in the gaps in imprecise memories: Simulating aging effects in younger adults" New paper from @michelleramey.bsky.social Read more here: www.sciencedirect.com/science/arti...
Qihong (Q) Lu reposted
Qihong (Q) Lu reposted
1/11 Happy to share our TICS paper on using the flexibility of one of the most basic cognitive functions, perception, to understand one of the most complex cognitive dysfunctions, psychiatric conditions (also my first formal work in computational psychiatry 🎉) 📄: www.cell.com/trends/cogni... 🧵 : 👇
Online Now: Perceptual multistability: a multifaceted window into brain dysfunctions
Qihong (Q) Lu reposted
Feeling really proud of this one: a review of Bayesian efficient coding with Máté Lengyel and Paul Bays (@bayslab.org) is now available online in TICS! authors.elsevier.com/a/1nF3i4sIRv...
Qihong (Q) Lu reposted
What is the relationship between memorization and generalization in AI? Is there a fundamental tradeoff? In infinitefaculty.substack.com/p/memorizati... I’ve reviewed some of the evolving perspectives on memorization & generalization in machine learning, from classic perspectives through LLMs.
Qihong (Q) Lu reposted
Super excited by this manuscript led by the amazing @brissend.bsky.social By combining fMRI, TMS, and modeling, we finally have causal evidence that the cerebellum is contributing to brain-wide working memory representations and recall performance! 1/n
Cerebellar perturbation impairs human working memory and degrades spatial tuning throughout cortex https://www.biorxiv.org/content/10.64898/2026.05.14.724968v1
Qihong (Q) Lu reposted
Qihong (Q) Lu reposted
🚨 New Preprint 🚨 I’m excited to share the first paper from my postdoc. We found age differences in the timescales of neural activity in the hippocampus during movie viewing 👀 These timescales were related to memory specificity in an interesting way (spoiler: the hippocampus may not be special!?)
Age Differences in Hippocampal Neural Timescales During Movie-Viewing https://www.biorxiv.org/content/10.64898/2026.05.05.723065v1
Qihong (Q) Lu reposted
THE NEURAL GEOMETRY SERIES The World Inside Neural Networks www.goodfire.ai/research/the...
Qihong (Q) Lu reposted
NEW PAPER! Here, my postdoc, Biru Dudhabhate, and I review the history of one of the most famous neuroscience hypotheses, the dopamine reward prediction error, and reflect on what made it such a major advance for the field. @uabneuro.bsky.social www.frontiersin.org/journals/com...
Qihong (Q) Lu reposted
Replying to @benhayden.bsky.social
Because this is a NeuroAI-flavored paper, Xinyuan and I decided to make a blogpost about it: psywalkeryanxy.github.io/posts/scienc...
Qihong (Q) Lu reposted
In collaboration with @monicarosenb.bsky.social , we showed that individual diffs in LTM encoding is uniquely predicted by inter-electrode correlations even controlling for working memory abilities. This suggests that WM & LTM encoding are separate abilities coded by different neural signatures! 1/n
New paper in Imaging Neuroscience by Chong Zhao, Edward K. Vogel, and Monica D. Rosenberg: A unique neural signature of long-term memory encoding from EEG inter-electrode correlation doi.org/10.1162/IMAG...
Qihong (Q) Lu reposted
New paper from the lab! "Plasticity and language in the anaesthetized human hippocampus" www.nature.com/articles/s41...
Qihong (Q) Lu reposted
Qihong (Q) Lu reposted
New paper out in cognition with @arikahn.bsky.social, @nathanieldaw.bsky.social, Cate Hartley, and @katenuss.bsky.social !! We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
Qihong (Q) Lu reposted
New Annual Review with @nathanieldaw.bsky.social: “Planning in the Brain: It's Not What You Think It Is.” We argue that the brain's 'planning' machinery is mostly used for learning from simulated experience, and that thinking prospectively at decision time is just one special case of this process.
Qihong (Q) Lu reposted
We're happy to release NeuralSet: a simple, fast, scalable package for Neuro-AI Supports: 🧠 fMRI, EEG, MEG, iEEG, spikes… preprocessing 💬 text 🔊 audio ▶️ video 🏞️ image… embeddings 📦 pip install neuralset 🔍 facebookresearch.github.io/neuroai/neur... 📄 kingjr.github.io/files/neural... 🧵 Details👇
Qihong (Q) Lu reposted
Neural circuits encode prior knowledge of temporal statistics www.nature.com/articles/s41...
Qihong (Q) Lu reposted
This is finally out as Version of Record 🎉 Read to find out how and when humans strategically switch between approaching and avoiding uncertainty with Michael Shadlen and Daphna Shohamy elifesciences.org/articles/94231 🧵:
Qihong (Q) Lu reposted
another great paper from @mh-christiansen.bsky.social, showing that non-constituents* can be primed It's more evidence that traditional linguists were mistaken to believe memory was in short supply: Human memory is compressed, clustered, implicit and vast
@adelegoldberg.bsky.social Have you seen this? Nielsen, Y. A., & Christiansen, M. H. (2026). Evidence for the representation of non-hierarchical structures in language. Nature Human Behaviour, 1–10. doi.org/10.1038/s415...
Qihong (Q) Lu reposted
Final paper of my PhD 🤗 www.nature.com/articles/s44... There is growing interest in how cognitive control may improve value-based decision making. However, we find that a recent paper overestimated the role of control in their task, leading to erroneous interpretations of dACC recordings.
Qihong (Q) Lu reposted
We are hiring a research specialist, to start this summer! This position would be a great fit for individuals looking to get more experience in computational and cognitive neuroscience research before applying to graduate school. #neurojobs Apply here: research-princeton.icims.com/jobs/21503/r...
Qihong (Q) Lu reposted
Does memory fade slowly, or in drops and bursts? We analyzed 728k tests from 210k people. Key finding: “stability” isn’t a trait you either have or don’t have - it’s often a time-limited state at different points in aging. Preprint "Punctuated Memory Change": 👇 www.biorxiv.org/content/10.6...
Qihong (Q) Lu reposted
Our experiences have countless details, and it can be hard to know which matter. How can we behave effectively in the future when, right now, we don't know what we'll need? Out today in @nathumbehav.nature.com , @marcelomattar.bsky.social and I find that people solve this by using episodic memory.
Qihong (Q) Lu reposted
Fantastic thread and a must-read for anyone working on spatial cognition.
Can humans & animals really use internal maps to take shortcuts? Tolman famously said yes - based largely on his Sunburst maze. Our new review & meta-analysis suggests evidence is far weaker than you might think. 🧵👇 doi.org/10.1111/ejn.... @uofgpsychneuro.bsky.social @ejneuroscience.bsky.social
Qihong (Q) Lu reposted
Qihong (Q) Lu reposted
What a privilege and a delight to work with @coltoncasto.bsky.social @ev_fedorenko and @neuranna on this new speculative piece on What it means to understand language, nicely summarized in this Tweeprint from @coltoncasto.bsky.social arxiv.org/abs/2511.19757
What does it mean to understand language? We argue that the brain’s core language system is limited, and that *deeply* understanding language requires EXPORTING info to other brain regions. w/ @neuranna.bsky.social @evfedorenko.bsky.social @nancykanwisher.bsky.social arxiv.org/abs/2511.19757 1/n🧵👇