Javeria Hashmi

Javeria Hashmi

@netphys.bsky.social

Neuroscientist: pain perception, human neuroimaging, networks and graphs, cautious Neuro AI, clinical translation

1.4K followers2.5K following151 posts

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Javeria Hashmi
@netphys.bsky.social

here is the correct link: www.researchgate.net/publication/...

researchgate.net(PDF) Chronic pain and the limits of artificial intelligence: why expert knowledge mattersPDF | AI is transforming chronic pain research, but without the right human input, it risks compounding the very problems it aims to solve. In our... | Find, read and cite all the research you need on...
Javeria Hashmi @netphys.bsky.social

New article: AI can transform chronic pain care, but without the right human input, it risks compounding the very problems it aims to solve. We suggest to build it in a way so that we can understand pain. Hashmi MA & Hashmi JA, PAIN (2026) doi.org/10.1097/j.pa... l1nq.com/lg9vhcq

researchgate.net(PDF) Chronic pain and the limits of artificial intelligence: why expert knowledge mattersPDF | AI is transforming chronic pain research, but without the right human input, it risks compounding the very problems it aims to solve. In our... | Find, read and cite all the research you need on...
Javeria Hashmi
@netphys.bsky.social

Thus, to experience pain properly, the brain requires a well established, well balanced network architecture in which bottom-up input and top-down context are properly integrated. An imbalance in network level processes may also have connotations for abnormalities in how pain is processed

Javeria Hashmi reposted

megan peters 🧠
@meganakpeters.bsky.social

check it out!

The Transmitter @thetransmitter.bsky.social

300 early-career neuroscientists commented on the future of the field in a new survey led by @neuromatch.bsky.social and @thetransmitter.bsky.social. #neuroskyence By Paige Miranda www.thetransmitter.org/science-and-...

thetransmitter.org‘High risk, high reward’: How early-career neuroscientists view their futureThe Transmitter and Neuromatch surveyed more than 300 early-career neuroscientists to better understand their unique challenges, career aspirations and support needs.

Javeria Hashmi reposted

Kayson Fakhar
@kayson.bsky.social

🚨 8 months after, this paper found its home at Science Advances. We came up with a generative brain network model based on game theory and found that the human brain is suboptimal both in terms of wiring cost and communication efficiency. Here's why: www.science.org/doi/10.1126/...

Kayson Fakhar@kayson.bsky.social

🚨new work with the dream team @danakarca.bsky.social @loopyluppi.bsky.social @fatemehhadaeghi.bsky.social @stuartoldham.bsky.social @duncanastle.bsky.social We use game theory and show the brain is not optimally wired for communication and there’s more to its story: www.biorxiv.org/content/10.6...

Javeria Hashmi reposted

Olivia Guest · Ολίβια Γκεστ
@olivia.science

> Claims made by Jason Arday, who was the subject of a relentless media campaign over many aspects of his work and life and who was found dead on Friday, appear to be true[.] Particularly mocked was Arday's claim that he ran 30 marathons in 35 days. But [it seems he] completed the challenge. 1/

Middle East Eye (Unofficial)@middleeasteye-rss.bsky.social

Jason Arday's marathon challenge and football claims found to be true after his death - https://www.middleeasteye.net/news/jason-ardays-marathon-challenge-and-football-claims-found-be-true-after-his-death

middleeasteye.netJason Arday's marathon challenge and football claims found to be true after his deathClaims the late academic made which were widely derided as false in media and online discourse this month appear to be true, an MEE analysis has found

Javeria Hashmi reposted

PAIN
@painthejournal.bsky.social

Lim et al. find that children experiencing pain and exposed to adverse life events showed accelerated brain maturation in emotion- and pain-associated regions, demonstrating additive effects on brain development. Learn more in #PAIN bit.ly/3SnUAmF

Javeria Hashmi
@netphys.bsky.social

1/ Chronic pain and post-traumatic stress symptoms (PTSS) co-occur very commonly, yet how they interact in the brain is unclear. New from our lab: trauma symptoms reorganize working memory circuits in chronic pain, even when behavior looks normal. Veinot & Hashmi, PAIN, 2026 🧵

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Javeria Hashmi
@netphys.bsky.social

8/ The takeaway: even trauma symptoms below the clinical threshold seem to reshape how prefrontal and brainstem circuits work together in chronic pain, and they do it through the emotional side of pain, not the physical. Maybe we should stop treating trauma and pain as separate problems.

Javeria Hashmi
@netphys.bsky.social

1/ Chronic pain and post-traumatic stress symptoms (PTSS) co-occur very commonly, yet how they interact in the brain is unclear. New from our lab: trauma symptoms reorganize working memory circuits in chronic pain, even when behavior looks normal. Veinot & Hashmi, PAIN, 2026 🧵

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Javeria Hashmi
@netphys.bsky.social

6/ Behavioral relevance: these patterns tracked depression and pain catastrophizing, but not pain intensity or disability. PTSS appears to act on the affective dimension of pain, suggesting changed affective regulation.

Javeria Hashmi
@netphys.bsky.social

7/ A subregion dissociation sharpened it further: dlPFC–dl/lPAG connectivity tracked arousal/reactivity symptoms; dlPFC–vlPAG tracked avoidance. This maps onto known active vs. passive coping roles of these PAG columns.

Javeria Hashmi
@netphys.bsky.social

1/ Chronic pain and post-traumatic stress symptoms (PTSS) co-occur very commonly, yet how they interact in the brain is unclear. New from our lab: trauma symptoms reorganize working memory circuits in chronic pain, even when behavior looks normal. Veinot & Hashmi, PAIN, 2026 🧵

View full thread
Javeria Hashmi
@netphys.bsky.social

4/ Task connectivity showed complementary effects. Higher PTSS scaled with stronger dlPFC–periaqueductal gray (PAG) coupling during task. Crucially, this was specific to PAG. No effect for amygdala or hippocampus, pointing to descending modulatory circuitry rather than general affective processing.

Javeria Hashmi
@netphys.bsky.social

5/ And connectivity and activations were linked: greater dlPFC–PAG connectivity predicted lower dlPFC recruitment at high load. Indicates prefrontal disengagement coupled to threat-circuit engagement under cognitive demand.

Javeria Hashmi
@netphys.bsky.social

1/ Chronic pain and post-traumatic stress symptoms (PTSS) co-occur very commonly, yet how they interact in the brain is unclear. New from our lab: trauma symptoms reorganize working memory circuits in chronic pain, even when behavior looks normal. Veinot & Hashmi, PAIN, 2026 🧵

Javeria Hashmi
@netphys.bsky.social

2/ 53 chronic low back pain participants did an N-back task during fMRI across four loads (0- to 3-back). We tested PTSS both dimensionally (PCL-5) and as a high/low split, and asked whether trauma load shapes task-evoked activation and connectivity.

Javeria Hashmi
@netphys.bsky.social

3/ Under the highest load (3-back), higher PTSS predicted reduced activation in left dlPFC and left IFGpo, core lateral prefrontal control regions. The effect was load-dependent: absent at low demand, emerging only when executive demand peaked.

Javeria Hashmi reposted

Mina Kimes
@minakimes.bsky.social

Had me cackling like a fool 😭

Rodger Sherman@rodger.bsky.social

Shrey spelling 32 words in 90 seconds to win the Spelling Bee is the new greatest athletic accomplishment of 2026. I don’t even know how he said the letters that fast. Got a “Holy Mackerel” out of @minakimes.bsky.social

Javeria Hashmi
@netphys.bsky.social

AI trained with input from experts: scientists, clinicians and patients, very carefully and cautiously may solve problems instead of creating new ones. See our paper:

PAIN@painthejournal.bsky.social

Hashmi et al. argue that AI and machine learning could transform chronic pain care by identifying objective biomarkers and patient subtypes, though rigorous validation and clinical integration remain essential. Learn more in #PAIN bit.ly/4cIZDpl

Javeria Hashmi reposted

David Seminowicz
@daspainbrain.bsky.social

discussion will include "potential interventions (e.g., moving to one competition per year, restricting applications, capping resubmissions)." don't miss this

Andrew Pruszynski@andpru.bsky.social

I encourage everyone to show up and make your voice heard at upcoming town halls and via any other channels: cihr-irsc.gc.ca/e/45096.html • Bilingual session: Thursday, May 28 at 1:00 p.m. ET • English session: Wednesday, June 24 at 1:30 p.m. ET • French session: Thursday, June 25 at 1:30 p.m. ET

cihr-irsc.gc.caWebinars - CIHRCIHR holds several webinars that allow us to share information, exchange ideas and discuss issues of importance with our stakeholders.

Javeria Hashmi reposted

Andrew Pruszynski
@andpru.bsky.social

I encourage everyone to show up and make your voice heard at upcoming town halls and via any other channels: cihr-irsc.gc.ca/e/45096.html • Bilingual session: Thursday, May 28 at 1:00 p.m. ET • English session: Wednesday, June 24 at 1:30 p.m. ET • French session: Thursday, June 25 at 1:30 p.m. ET

cihr-irsc.gc.caWebinars - CIHRCIHR holds several webinars that allow us to share information, exchange ideas and discuss issues of importance with our stakeholders.
Andrew Pruszynski@andpru.bsky.social

CIHR has launched a trial ballon that suggests shifting to one competition a year. This is the worst idea I have heard in a long time. The only benefit is making top-line success rates look better than they are. Keep it as is, do in-person reviews, and keep the pain in the open.

Javeria Hashmi reposted

Steven Meisler
@stevenmeisler.com

Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development. 🔗 www.biorxiv.org/content/10.6...

Javeria Hashmi
@netphys.bsky.social

Hermann Hesse // "This day will never come again and anyone who fails to eat and drink and taste and smell it will never have it offered to him again in all eternity. The sun will never shine as it does today...You must play your part and sing a song, one of your best."

Javeria Hashmi
@netphys.bsky.social

Come work with us on pain modulation, placebo, phenotyping with ML, and machine learning, big data. Apply for Canada Impact+ Research Training Awards ORS deadline: May 13, 2026 Dalhousie has been allocated 4 doctoral and 3 postdoctoral nominations. Email me for details

Javeria Hashmi
@netphys.bsky.social

Key takeaways: -Chronic pain lacks objective biomarkers, making AI predictions especially vulnerable to misinterpretation -Expert-driven feature selection improves both model performance AND fairness -Explainable AI is essential; black-box systems undermine clinical trust and patient autonomy

Javeria Hashmi
@netphys.bsky.social

-Transdisciplinary teams are a necessity, not a nicety, for equitable pain care -AI can help us move toward personalized, scalable pain care, but needs to be built with human oversight to be most effective

Javeria Hashmi
@netphys.bsky.social

More evidence that the homeostatic pathway lamina 1 theory has no feet.

Micah G. Allen@micahgallen.com

Is there a single "interoceptive sense"? Our new study in @commspsychol.nature.com says: probably not. In 241 participants, cardiac and respiratory interoception were completely uncorrelated — only subjective confidence was shared across domains. www.nature.com/articles/s44... #psychscisky 🧪

Javeria Hashmi reposted

Kate Nautiyal
@katenautiyal.bsky.social

Check out our new paper, and join this webinar where @drjkhokhar.bsky.social and I will discuss the science and more! www.eneuro.org/content/13/2...

eneuro.orgThe Serotonin 1B Receptor Modulates Striatal Activity Differentially Based on Behavioral ContextThe dorsomedial striatum (DMS) is critical for both motivating and inhibiting behavioral responses. The region integrates inputs from the cortex, thalamus, and other subcortical structures including m...
SfN Journals@sfnjournals.bsky.social

Register now for the next #ResearchInConversation webinar on March 12, noon EDT 🔗 Register: https://neuronline.sfn.org/scientific-research/the-serotonin-1b-receptor 📄 Read the #JNeurosci paper: https://doi.org/10.1523/ENEURO.0413-25.2026

Javeria Hashmi reposted

Jibran Khokhar
@drjkhokhar.bsky.social

Excited to share this in final form @sfnjournals.bsky.social: An Open-Source Restraint System for Magnetic Resonance Imaging in Awake Rats www.eneuro.org/content/13/2... if anyone wants to try doing it, give us a call! Happy to help you get going!

eneuro.orgAn Open-Source Restraint System for Magnetic Resonance Imaging in Awake RatsMagnetic resonance imaging (MRI) is a critical tool for translational neuroscience, but preclinical studies frequently rely on anesthesia, which alters neural activity and limits comparison with human...