gavin leech

gavin leech

@gleech.org

context maximizer https://gleech.org/

1.3K followers354 following400 posts

I figure you lot need this thread more than your Twitter counterparts

gavin leech@gleech.org

Hard to believe how bad this piece is; each answer contains at least one straightforward falsehood or fallacy

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(I can agree, though, that it is stupid to make superhuman hackers in the first place, and stupid to run security as they have been.)

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“None of the steps in this argument is credible” If Jordan is using “brain” as a metaphor for neural nets, then a weak form of the above, data parallelism, happens every day. (Hinton does believe in swarm updates - not obvious or publicly known, but highly credible) www.reddit.com/r/agi/commen...

reddit.comFrom the agi community on Reddit: Geoffrey Hinton says agents can share knowledge at a scale far beyond humans. 10,000 agents can study different topics, sync their learnings instantly, and all improv...Explore this post and more from the agi community

“OpenAI agents hacked [HF]… they were conducting rather stupid experiments, letting the agents do whatever they wanted and encouraging this behavior.” Wrong: 1) their eval sandbox had no internet access; 2) their prompt forbade HPIM's methods, 3) their grader didn’t (explicitly) reward it.

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"at these companies… Many of them aren’t really engineers; they come from the humanities… they don’t do engineering work…” Anthropic’s technical arm is 40% hardcore infra people; their median prior work experience is 12 years; <1% have a philosophy background www.htx.com/pt-pt/news/w...

htx.comWhat Kind of People Is Anthropic Actually Hiring? Insights from 1,680 Resumes Provide the Answer | Perceções da HTXContrary to the common perception of Anthropic as a PhD-heavy AI research lab, an analysis of 1,680 engineer profiles reveals its core talent is experienced "builders." The engineering team, largely a...

You can't buy melatonin in the UK. In the US, it's hard to avoid: it's in gas station soft drinks. How general is this kind of thing? Our new beige site looks at every case where medical regulators disagree about whether to approve a medicine. We found 101 instances www.juriscription.info/results

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We did all the data work before Claude Code existed; I hope to trick one of you into doing better than us. Should take a weekend (:

Thanks for huge amounts of tedious work by Rian O'Mahoney, Paul Crowe, Phil Harrison, and Jacob Slosser. Huge thanks to Emergent Ventures for funding this work. Grudging thanks to Ben Southwood for bullying me into doing something concrete to improve the world for once

You can't buy melatonin in the UK. In the US, it's hard to avoid: it's in gas station soft drinks. How general is this kind of thing? Our new beige site looks at every case where medical regulators disagree about whether to approve a medicine. We found 101 instances www.juriscription.info/results

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Serious caveats: We manually inspected the outputs of the pipeline, but there are 200,000 rows here and we're not pharmacists. The 2026 models would do a lot better but we're out of patience. It's not obvious what fraction of discordances *should* resolve to universal approval

You can't buy melatonin in the UK. In the US, it's hard to avoid: it's in gas station soft drinks. How general is this kind of thing? Our new beige site looks at every case where medical regulators disagree about whether to approve a medicine. We found 101 instances www.juriscription.info/results

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* If you like data gore, this is the worst data I've seen in a long career, and lives are at stake here * If you've just moved countries, you can also look up the equivalent of your favs

You can't buy melatonin in the UK. In the US, it's hard to avoid: it's in gas station soft drinks. How general is this kind of thing? Our new beige site looks at every case where medical regulators disagree about whether to approve a medicine. We found 101 instances www.juriscription.info/results

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Still, over a full damn year we had a go with huge amounts of manual work on top of Claude's virtual work. We only got around to doing US, UK, and EU. Caveat aegrotus

What's the point?: * I was looking to get ambroxol and melatonin approved in the UK, and dreamt that there would be many others. We'll see. * Use cross-country data to draw attention to the arbitrariness of decisions * Help people look up where to get meds they can't get at home

You can't buy melatonin in the UK. In the US, it's hard to avoid: it's in gas station soft drinks. How general is this kind of thing? Our new beige site looks at every case where medical regulators disagree about whether to approve a medicine. We found 101 instances www.juriscription.info/results

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Various countries have "regulatory recognition agreements", where they can reuse each other's work and get things approved quickly if it's already approved in a sensible jurisdiction. So THEN (one thought) one could use these agreements to get hundreds of meds approved elsewhere

Surely (one thought), AI is good enough now to make this a weekend job. Unfortunately not. It's nearly unbelievable how messy and ambiguous pharma data is. One pharma company, Novartis (75000 employees), needs around 3000 analysts, statisticians, data guys to function.

You can't buy melatonin in the UK. In the US, it's hard to avoid: it's in gas station soft drinks. How general is this kind of thing? Our new beige site looks at every case where medical regulators disagree about whether to approve a medicine. We found 101 instances www.juriscription.info/results

A while back I noticed a bunch of "discordances" (medicines banned or unapproved in one country, but approved, even OTC, in another)

A jaundiced thread on OpenAI's (broadly quite good) New Deal policies. *Most* of these ideas have massive unflagged conflicts of interest

gavin leech reposted

I am not going to be able to latch onto the latest cool trend because several extremely clever people who I've known for years and respect immensely are currently producing very good work with AI. It would be more socially convenient if this wasn't true but it is.