Our new project unveiling an integrative single-fiber framework that connect multi-omic cellular heterogeneity to molecular function in ICU-related muscle wasting! Congratulations to all authors especially Alexandra who led the whole project! Thank you to @lundbeckfonden.bsky.social for the support
Julien Ochala
Julien Ochala
@droch.bsky.social
Associate Professor at the University of Copenhagen - https://bmi.ku.dk/english/research/exercise-and-muscle/ochala-group/
636 followers550 following95 posts
Very interesting study unravelling cardiac myofibrillar plasticity in the animal kingdom! Huge effort from colleagues at CU Boulder (with very humble contribution from our lab)
Postdoc opportunity in our group in sunny Copenhagen ☀️ candidate.hr-manager.net/ApplicationI...
Our latest collaborative work highlighting an early cardiac myosin dysfunction in diabetic patients (even without any cardiomyopathy)! @ucph.bsky.social funded by @novo-nordisk.bsky.social
Impressive study!
Julien Ochala reposted
When to target the most abundant protein in the heart? @droch.bsky.social & team show myosin becomes maladaptive in X-linked myotubular myopathy, consuming excessive energy, and inhibiting its ATPase activity in mice partly rescues the molecular defects: doi.org/10.1172/jci....
Our team at Københavns Universitet - University of Copenhagen will soon be looking for a postdoc with experience in AI-driven vHTS and cardiac sarcomere modeling. If interested please send me an email. Spread the word :-)
Great collaborative work led by Christopher Toepfer and his team at the University of Oxford
Julien Ochala reposted
We are recruiting a Reader/Professor of Immunobiology at @kingslsm.bsky.social . This is a unique opportunity to shape basic immunology at @kingscollegelondon.bsky.social . Please RP. www.kcl.ac.uk/jobs/131447-...
Our collaborative effort unravelled puzzling results warranted more research on the topic of myosin and cardiac chamber specificities @ucph.bsky.social
Excited to present our recent work on myosin as a molecular target for genetic muscle diseases! Kudos to all authors, especially Elise, Fanny and @myofinlab.bsky.social @ucph.bsky.social
Julien Ochala reposted
Recruiting a comp PDRA for the lab 🚨 Working on multiple projects using integrated multi omics in bulk & single cell level Passion for data, coding, bioinformatics & keen to lead our labs comp workflow 12 months in first instance but extendable for further 19 months my.corehr.com/pls/coreport...
Multilingualism protects against accelerated aging www.nature.com/articles/s43...
Julien Ochala reposted
We are grateful to Independent Research Fund Denmark for funding our new project aiming to understand and treat heart failure! The project will take place at @ucph.bsky.social
Julien Ochala reposted
Ensure #ISHLT2026 will be next level. ▶️ Submit your science in the treatment of advanced #heart and #lung disease, #transplantation, #MCS, and #PVD by 📆 14 October: 🔗 https://bit.ly/4dLYGdn
We are looking for an enthusiastic MD or PhD to work on a postdoc project on the molecular mechanisms underlying human hibernating myocardium and ischemic cardiomyopathy. If interested send me an email! #heart #cardiomyopathy #sarcomere
Julien Ochala reposted
🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important Good collab with @droch.bsky.social so travel to CPH involved as well www.kcl.ac.uk/jobs/126245-...
This trial has been stopped for strategic business reasons
Postdoc opportunity in muscle cell biology! You would not only be involved in an ambitious project but would also help develop cutting edge methods! Highly recommended! @robertseaborne.bsky.social
Julien Ochala reposted
UAB and Children's of AL is looking for a new Division Director of Pediatric Neurology (come be one of my bosses!). We are consistently in the top 30 nationwide in Pediatric Neurology and have excellent subspecialties in: Epilepsy, Autism, and NMDs. Apply: tinyurl.com/y8d8duve
Julien Ochala reposted
Please repost! We have an open rank, tenure-line faculty position in biomechanics in the School of Kinesiology at the University of Michigan Ann Arbor. At U-M we have great colleagues, exceptional resources, and biomechanics can be found all across the campus. #BiomechSky
Julien Ochala reposted
Such a great city for science and culture 🇨🇦💕
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!
Julien Ochala reposted
Very happy to have been awarded a NIRG from the MRC. Stay tuned for some exciting (I think, but being biased) postdoc positions within our lab!
Congratulations to Dr Robert Seaborne @kingscollegelondon.bsky.social who has been awarded a New Investigator Grant from the Medical Research Council (MRC), which will support his work on understanding the role of skeletal muscle in motor neurone disease. Read more ➡️ www.kcl.ac.uk/news/dr-robe...
Application submitted to @novo-nordisk.bsky.social - 🤞 - on to next one now!
Julien Ochala reposted
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social
Julien Ochala reposted
Interested in nuclear #mechanobiology? Join us for the first ever FASEB Science Research Conference on the Mechanobiology of the Nucleus #MBNSRC. Find more information and register at: events.faseb.org/event/Mechan... Submit abstracts by August 31, 2025. Please share and see you in October!
Julien Ochala reposted
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
Our department @ucph.bsky.social is looking for a new faculty member! This is a nice environment for an ambitious PI with a research focus on cardiovascular system, metabolism and/or drug discovery! Happy to answer questions if you are interested!
Julien Ochala reposted
Damien M. Callahan presents this #TranslationalPerspective on the work of Laitila et al. linking altered structure and post-translational modification of Troponin T to dystonia in nemaline myopathies💭 ✍️ 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Julien Ochala reposted
Looking for a #LifeSciences postdoctoral #opportunity? 🧪 Have a look at the EMBO Postdoctoral Fellowships for internationally mobile scientists in #Europe and globally. Apply before 11 July: www.embo.org/funding/fell... #research #funding #postdoc
Julien Ochala reposted
Save the date! On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility news.ki.se/ki-to-recruit-junior-researchers-with-a-focus-on-excellence
Julien Ochala reposted
Great review article on metabolism and HCM led by @edgarnollet.bsky.social #cardiosky
Julien Ochala reposted
Last chance to register (attend online or in person) and/or submit an abstract to @sma-europe.bsky.social 1st International Clinical Care. Deadline is June 15th! Registration: na.eventscloud.com/ereg/newreg.... Abstract submission: na.eventscloud.com/eSites/sma20...
Julien Ochala reposted
Registration for the Joslin Diabetes Symposium 2025 is now open. Focus is on inter-organ and international communication and the event is supported by friends in Canada and Denmark (Steno-DK)! 🇫🇴🇨🇦🇺🇸🇬🇱🇩🇰 More info 👇 @novonordisk.bsky.social #Steno-DK #Joslin #Toronto joslinsymposium.org
Offre de stage Master 2 @ucph.bsky.social dans le domaine des maladies cardiaques #CardioSky
Julien Ochala reposted
Thrilled to share that our manuscript mapping proteomic & phosphoproteomic signatures of NGT, T2D, males & females — before and after hyperinsulinemic-euglycemic clamp — is now accepted in Cell. @annakrook.bsky.social @juleenrzierath.bsky.social @cbmr.science doi.org/10.1016/j.ce...
Julien Ochala reposted
Very enjoyable collaboration with puzzling results on myosin and HCM @ucph.bsky.social @amsterdamumc.bsky.social @novo-nordisk.bsky.social
Julien Ochala reposted
Julien Ochala reposted
Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social www.science.org/doi/epdf/10....
Julien Ochala reposted
Excited to see (newly Dr) Greg Milburn's paper on cardiac amyloidosis in human myocardium with cell-level mechanics, histology, and gel-based analysis of sarcomeric proteins. Myocardium From Patients With ATTR Amyloidosis Produces Less Force Secondary to Increased Fibrosis doi.org/10.1016/j.ja...
Julien Ochala reposted
The most abundant skeletal muscle protein (myosin) becomes super-relaxed and energy-efficient in type 2 diabetes mellitus #T2D #DiabetesResearch link.springer.com/article/10.1... 🔓
Julien Ochala reposted
Come join us at @westernuresearch.bsky.social as a Canada Excellence Research Chair! DM me with questions/interest about theme 2! Be a part of a strong and well-equipped (e.g., imaging, behaviour) neuroscience community! uwo.ca/research/cer... @westernuwin.bsky.social @westernubrainscan.bsky.social