Bassem Hassan

Bassem Hassan

@bassemh.bsky.social

World citizen, Time and Variation in Brain Development, football, cheese, wine, single malt!

765 followers679 following44 posts

Bassem Hassan reposted

The Hassan Brain Development Team
@hassanbraindevlab.bsky.social

A conversation between Alan Rodrigues and Bassem Hassan @bassemh.bsky.social on the YouTube Conceptual Biology Forum channel about how living systems self-organise and consequences to our understanding of brain development, function, health and disease. www.youtube.com/watch?v=r6qZ...

youtube.comNeuronal systems: bridging ontogeny and function | Bassem Hassan | CBF Dialogues 004YouTube video by Conceptual Biology Forum
Bassem Hassan
@bassemh.bsky.social

Maheva @maheandria.bsky.social is a scientist through and through. An original and deep thinker, and a rigorous experimentalist. Can’t wait to see the beautiful work of her lab in the years to come.

The Hassan Brain Development Team@hassanbraindevlab.bsky.social

We are excited and proud to share that the super talented @maheandria.bsky.social will be starting her own lab as an assistant professor and group leader at @neuropsi.bsky.social this fall 🥳🍾

Bassem Hassan reposted

The Hassan Brain Development Team
@hassanbraindevlab.bsky.social

Ania Chrzanowska and @bassemh.bsky.social discuss why it is informative to think about neuronal circuit function from a developmental perspective. www.sciencedirect.com/science/arti...

sciencedirect.comBuilding brains, shaping behaviors: How developmental approaches illuminate the analysis of circuits and behaviorDevelopmental processes define the parameters of neural circuits and restrict the range of possible behaviors. Here, we briefly highlight how the deve…

Bassem Hassan reposted

Einstein Foundation Berlin
@einsteinberlin.bsky.social

Herzlichen Glückwunsch an den ehemaligen Einstein Visiting Fellow Bassem Hassan @hassanbraindevlab.bsky.social 🎉

Freie Universität Berlin @freieuniversitaet.bsky.social

Internationale #Spitzenforschung in Berlin: Prof. Dr. Bassem Hassan hassanbraindevlab.bsky.social vom #ParisBrainInstitute kommt mit dem Humboldt-Forschungspreis an die #FUBerlin und bringt neue Perspektiven auf die Entwicklung des Gehirns mit. 🧠 ℹ️ www.fu-berlin.de/presse/infor...

Bassem Hassan
@bassemh.bsky.social

I want to thank my friend, colleague and long term collaborator the social media-less Prof. Robin Hiesinger for nominating me and look forward to many more years of exciting intellectual exchanges and experimental collaborative work

Bassem Hassan
@bassemh.bsky.social

I am grateful and excited to receive the Humboldt-Forschungspreis (Humboldt Research Award) from the @humboldt-foundation.de I look forward to inspiring interactions with this amazing scientific community. Thank you to Prof Robin Hiesinger for the nomination and the award committee for selecting me.

Bassem Hassan
@bassemh.bsky.social

It was areal pleasure to visit and exchange with colleagues about the beautiful science being done. Thank you for having me!

Instituto de Neurociencias CSIC-UMH@neuroalc.bsky.social

Today we had the pleasure of hosting Dr. Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social at our #SeminarsIN with his talk: “Temporal control of neurogenesis” A fantastic lecture, thank you! 👏👏 @csic.es @dicv.csic.es @umh.es @borrell-lab.bsky.social

Bassem Hassan
@bassemh.bsky.social

Thank you for the invitation. Really looking forward to the visit.

Instituto de Neurociencias CSIC-UMH@neuroalc.bsky.social

We have the pleasure of welcoming Dr Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social tomorrow at #SeminarsIN 🙌 He is a world leader in the study of genetic regulation of brain development. Don’t miss it! @borrell-lab.bsky.social @csic.es @dicv.csic.es @umh.es

Bassem Hassan
@bassemh.bsky.social

Julien Pigeon and colleagues show how conserved processes can be fine tuned to result in species-specific patterns of brain development. Thanks to @alexbaffet.bsky.social @boyanbonev.bsky.social @neurogenesis-i3s.bsky.social for a great collaboration 👇🏽

The Hassan Brain Development Team@hassanbraindevlab.bsky.social

www.biorxiv.org/content/10.1... Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis

biorxiv.orgPost-translational Tuning of Human Cortical Progenitor Neuronal OutputThe striking expansion of the human neocortex is driven by the ability of radial glial cells (RGCs) to prolong neurogenesis without exhausting their progenitor pool, thereby producing more neurons, pa...

Bassem Hassan reposted

The Hassan Brain Development Team
@hassanbraindevlab.bsky.social

Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder. www.linkedin.com/posts/bassem...

linkedin.comHeterozygous pathogenic variants in the splicing factor SF1 lead to a large spectrum of neurodevelopmental disorders | Bassem HassanLatest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder.

Bassem Hassan reposted

The Hassan Brain Development Team
@hassanbraindevlab.bsky.social

For those who understand Arabic 😊 A podcast about @bassemh.bsky.social work and career. Thank you Haifa Alhadyian, PhD for this amazing initiative. www.linkedin.com/posts/activi...

linkedin.comالحلقة الأولى من بودكاست "مقابلات مع علماء عرب حول العالم" متاحه للإستماع الآن 🎙️ 🧠 🔬 .. ضيفي للحلقة الأولى هو الدكتور باسم حسن (Bassem Hassan)، قائد فريق في معهد باريس للدماغ في فرنسا في ...الحلقة الأولى من بودكاست "مقابلات مع علماء عرب حول العالم" متاحه للإستماع الآن 🎙️ 🧠 🔬 .. ضيفي للحلقة الأولى هو الدكتور باسم حسن (Bassem Hassan)، قائد فريق في معهد باريس للدماغ في فرنسا في تخصص علم ا...

Bassem Hassan reposted

The Hassan Brain Development Team
@hassanbraindevlab.bsky.social

Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social labs www.nature.com/articles/s41...

nature.comTemporal transcriptional regulation of mitochondrial morphology primes activity-dependent circuit connectivity - Nature CommunicationsThis study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal re...

Bassem Hassan reposted

EXPeditions
@expeditions.bsky.social

“How does a brain take shape?” Neurobiologist @bassemh.bsky.social on the embryonic cells that fold into the neural tube and become the brain. Discover more in The Brain’s Secret. #Biology #Neuroscience #Brain #Education #ReliableKnowledge #PublicEngagement

Bassem Hassan reposted

Pierre Vanderhaeghen
@vanderhaeghenp2.bsky.social

Fantastic opportunity for neuroscience research. The ROGER DE SPOELBERCH Prize for a basic or clinical research project in the areas of neurodegenerative diseases or psychiatric disorders. 750.000 EUR - Deadline JUNE 30 2025. www.fondation-roger-de-spoelberch.ch/en/roger-de-...

fondation-roger-de-spoelberch.chROGER DE SPOELBERCH Prize | Fondation ROGER DE SPOELBERCHEach year, the Foundation awards the ROGER DE SPOELBERCH Prize to a laureate for a clinical or fundamental scientific research project in the field of neurodegenerative diseases and certain psychiatri...

Bassem Hassan reposted

Nature Neuroscience
@natneuro.nature.com

A temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circuits in Drosophila 🧪🧠 @bassemh.bsky.social @maheandria.bsky.social @hassanbraindevlab.bsky.social @institutducerveau.bsky.social www.nature.com/articles/s41...

nature.comSequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster - Nature NeuroscienceThe developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circu...

Bassem Hassan reposted

The Hassan Brain Development Team
@hassanbraindevlab.bsky.social

New from the lab: @maheandria.bsky.social and colleagues in collaboration with the Hiesinger, Stoeckli and von Kleist labs dissect the sequential emergence of axonal targeting during development in today's issue of Nature Neuroscience: rdcu.be/ek010

rdcu.beSequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogasterNature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...
Bassem Hassan
@bassemh.bsky.social

@maheandria.bsky.social and I challenge the notion of a static and deterministic definition of a (neural) cell type and argue for its replacement by a multi parametric probabilistic definition in this perspective sciencedirect.com/science/arti...

sciencedirect.comToward a probabilistic definition of neural cell typesA classical view of cell type relies on a definite set of stable properties that are critical for brain functions. Single-cell technologies led to an …

Bassem Hassan reposted

The Hassan Brain Development Team
@hassanbraindevlab.bsky.social

Anna CHRZANOWSKA, PhD, postdoc in The Hassan Brain Development Team @hassanbraindevlab.bsky.social is organizing a trainee-led symposium @institutducerveau.bsky.social June 2-4 Spread the word! nenckiopenlab.org/decoding/

nenckiopenlab.orgNencki Open LabDecoding the brain: from methods to meaning Paris Brain Institute, June 2-4th 2025 Applying machine learning and other models to decode behavioral parameters from neural activity is now a standard …
Bassem Hassan
@bassemh.bsky.social

I contend that the genome does not encode a mean and an error around it. It encodes a distribution. I would suggest that even evolutionary selection is on phenotypic distributions. The mean is just an emergent property of the distribution, and thus not in and of itself interesting to understand.

Bassem Hassan reposted

Alicia Hidalgo Lab
@aliciahidalgolab.bsky.social

Last few days to apply! Post-doctoral position 3 years Wellcome funded in UK To investigate how experience shapes the brain Drosophila neurogenetics, imaging, behaviour Deadline 19/3/25 Pls RP. #drosophila #postdoc #jobs Apply here edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

edzz.fa.em3.oraclecloud.comResearch Fellow in Neurogenetics to investigate how experience shapes the brain - School of Biosciences - 98709 - Grade 7A Research Fellow with experience in behavioural neurogenetics of Drosophila is sought. The aim of the project is to investigate how experience and behaviour shape the brain throughout life, the impac...
Bassem Hassan
@bassemh.bsky.social

Just a little stream of thoughts: As materialists (i.e. non-dualists) we believe that there is only the universe out there an nothing outside it that imposes anything on it and that the universe is made of matter and energy (and they are interchangeable and I will thus only refer to matter)...

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Bassem Hassan
@bassemh.bsky.social

I may be making some fundamental error in this logical chain, but it seems to me that accepting strict materialism necessitates concluding that causality is an emergent property that has different characteristics at different scales and evolves over time (whatever that is)...

Bassem Hassan
@bassemh.bsky.social

If so, then it is legitimate to 1) ask, 2) seriously think about and 3) define quite specifically what we mean when we talk about causality and make causal inferences for something as complex and emergent as biological systems are... That it. That's the thread. Thanks!

Bassem Hassan
@bassemh.bsky.social

Just a little stream of thoughts: As materialists (i.e. non-dualists) we believe that there is only the universe out there an nothing outside it that imposes anything on it and that the universe is made of matter and energy (and they are interchangeable and I will thus only refer to matter)...

View full thread
Bassem Hassan
@bassemh.bsky.social

This in turn means that the "laws of nature" are consequences of matter (i.e. descriptions) and its behaviour not causes of it and external governors of its behaviour. Therefore, the laws of nature are emergent and not fundamental and, to paraphrase Lee Smolin, they potentially evolve over time...

Bassem Hassan
@bassemh.bsky.social

Finally, and this is really the point I want to get to, does this not mean that causality itself is an emergent property of matter? If so, then causality only applies starting at a certain scale (which?) and it may have different properties at different scales...

Bassem Hassan
@bassemh.bsky.social

Just a little stream of thoughts: As materialists (i.e. non-dualists) we believe that there is only the universe out there an nothing outside it that imposes anything on it and that the universe is made of matter and energy (and they are interchangeable and I will thus only refer to matter)...

Bassem Hassan
@bassemh.bsky.social

It necessarily follows that everything that happens in the universe is a result of the interactions of matter and energy. It also necessarily follows that these interactions are not governed by "laws" that are outside matter itself...

Bassem Hassan reposted

the Node
@the-node.bsky.social

"Developmental Timing Across Species" @embo.org Workshop organised by @trayon.bsky.social @bassemh.bsky.social @mdiazcuadros.bsky.social @vanderhaeghenp2.bsky.social 📅6-9 May 2025 📍Paris Submit abstract and register by 1 April: thenode.biologists.com/developmenta... #EvoDevoTempo

thenode.biologists.comDevelopmental timing across species | EMBO Workshop | 6-9 May - the NodeJoin us at the EMBO Workshop "EvoDevoTempo – Developmental Timing Across Species: From Mechanisms to Evolutionary Insights". Topics will include