varshram.bsky.social

varshram.bsky.social

@varshram.bsky.social

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varshram.bsky.social
@varshram.bsky.social

Happy to share my first preprint! We looked at how the 3D genome changes during red blood cell differentiation, especially at erythroid CREs. It was fun to work on this collab with many wonderful people from the @andersshansen.bsky.social and @bloodgenes.bsky.social labs esp. Chun-Jie.

Anders Sejr Hansen@andersshansen.bsky.social

(1/n) Excited to share close collab w @bloodgenes.bsky.social led by Varshini & Chun-jie et al How to induce expression of key genes while silencing much of the genome during Erythropoiesis? A: Matchmaker CREs load cohesin near key genes to promote looping & exp: www.biorxiv.org/content/10.6...

varshram.bsky.social reposted

claricehongky.bsky.social
@claricehongky.bsky.social

Excited to share my first preprint from the @andersshansen.bsky.social lab! It's got genomics, AI, and biology - all wrapped up in a great paper. Also very grateful to my amazing collaborator, Fan, for all his hard work. Please check it out and let me know what you think! tinyurl.com/bdfvtd6f

tinyurl.comGenome structure mapping with high-resolution 3D genomics and deep learningGene expression is often regulated by distal enhancers through cell-type-specific 3D looping interactions, but comprehensive mapping of these interactions across cell types is experimentally intractab...

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