The Lancet

The way digital technologies are built & governed creates real health risks worldwide. In a new issue, a Series links digital media use to mental health & sleep problems plus reduced physical activity. Authors call for urgent, coordinated action. Read this & more: spkl.io/633217kyih

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies. In @lancetgastrohep.bsky.social, a Review evaluates the clinical development of therapeutic cancer vaccines in PDAC: spkl.io/633267kQT2

Early-onset colorectal cancer (EO-CRC) is increasing globally. In The Lancet Regional Health - Eastern Mediterranean, authors assessed the burden, temporal trends, and future projections of EO-CRC across the WHO Eastern Mediterranean Region: spkl.io/633287kJDY

Use of an AI chatbot ahead of GP appointments required no safety interventions in first real-world small study. However, authors caution that this study doesn't suggest AI chatbots are able to diagnose or triage patients without a doctor's oversight. spkl.io/633267kySA

📣 Extended deadline: Nov 6 Still time to present your research: Submit abstracts on women’s cancers, haematological cancers, or cancer imaging to the #LancetSummit and help shape the future of #CancerControl in China and beyond: spkl.io/633297XLAb

Presented today at #MSToronto2026: The REMODEL-1 and REMODEL-2 studies find that remibrutinib was superior to teriflunomide in patients with relapsing multiple sclerosis, while maintaining a favourable safety profile. Explore the research: spkl.io/633297kz4D

Adding a hormonal coil during surgery for heavy menstrual bleeding reduces future hysterectomy risk by more than half, trial finds. Find out more in The Lancet: spkl.io/633217Xx4L

AI tool can predict cancer patients’ chances of survival from a single face photograph, study suggests. Find out more in The Lancet Digital Health: spkl.io/633267XBMw

By 2050, almost 1 billion people are expected to live with osteoarthritis—a disabling musculoskeletal condition with currently no cure. A new Health Policy outlines a roadmap for global health policy to prioritise, provide care, and prevent osteoarthritis: spkl.io/633207XBra

GLP-1s associated with reduced need for acute psychiatric care for people with schizophrenia and type 2 diabetes, study of US data suggests. Find out more in @thelancetpsych.bsky.social: spkl.io/633257X6fJ

ICYMI—New antibody treatment reduces number of new abnormal bone lesions by at least 90% in people with ultra-rare genetic disorder, fibrodysplasia ossificans progressiva (FOP), phase 3 study shows. Read now: spkl.io/633227X6ri

Hashimoto's thyroiditis is the most frequent autoimmune thyroid disease & the leading cause of hypothyroidism. In @thelancetendo.bsky.social, a Review summarises developments over the past two decades and considers emerging approaches to precision medicine: spkl.io/633247nbZM

ICYMI - Radiotherapy after surgery halves risk of recurrence in a type of brain tumour that can often grow back, trial shows. Find out more in The Lancet: spkl.io/633257VNLl #EANO2026 @eanoassociation.bsky.social

TRIUMPH-2 findings suggest that retatrutide might advance the treatment of people with obesity and type 2 diabetes, showing bodyweight reduction alongside improvements in glycaemic control and cardiometabolic risk factors. Read more: spkl.io/633207VNIE #EASD2026

What will shape the health of the next generation? The Lancet Commission on 21st Century Threats to Health identified 17 catastrophic threats, drawing on expertise from health, economics, security, governance, and technology. @thelancet.com Read more: ms.spr.ly/63321aqvhJ

🧠 Migraine is a chronic neurological disorder that affects over 1 billion people globally each year, with women predominantly affected. A new Seminar discusses typical symptoms, mechanisms, and treatment options: spkl.io/633257VNQH

From trainee physician to CEO of Gavi, what can Dr Sania Nishtar's career journey tell us about the future of global health? Hear her insights at our International Health Lecture with @acmedsci.bsky.social 🌎 Register: spkl.io/633217VICN

Use of an AI chatbot ahead of GP appointments required no safety interventions in first real-world small study. However, authors caution that this study doesn't suggest AI chatbots are able to diagnose or triage patients without a doctor's oversight. spkl.io/633297VfkR

Ahead of #WorldMentalHealthDay, our Editorial highlights the value of lived experience in mental health research and services, alongside critical challenges in its implementation. Read now: spkl.io/633257VNub

On the cover, a Review provides a series of roadmaps for advancing practice, research, and policy in the arts and health. Read this & more: spkl.io/633267VNlQ

🆕 Out now: The Lancet Regional Health – Eastern Mediterranean’s inaugural issue. #goldopenaccess “The scale of the challenges the region has faced this past year can be hard to absorb. It is in this context that this journal takes shape.” Explore the new issue: spkl.io/633277VQx7

Join IHME at @worldhealthsummit.bsky.social on Oct. 11! 5:00–6:30 a.m. PDT / 14:00–15:30 CEST — The Launch of @thelancet.com Commission on 21st Century Global Threats to Health Learn more about this session & tune in live: ms.spr.ly/63328aogdu

Now online @thelancet.com: a new Seminar on migraine, covering epidemiology, clinical presentation, diagnosis, and outcomes, pathophysiology, and treatment www.thelancet.com/journals/lan...

Can we delay the progression of type 1 diabetes? Join Chantal Mathieu at The #LancetSummit (Nov 30-Dec 2, Sitges) to explore the latest advances in #T1D. Register by Oct 31, 2026 using voucher code TLDC100 to save €100: spkl.io/633257VXhZ

Three- and four-year-olds take over 18,500 steps a day on average, study suggests. However, step counts varied widely across participants. Find out more in @lancetchildadol.bsky.social: spkl.io/633207p2Ty

Stereotactic body radiation therapy (SBRT) is the standard of care for early-stage, medically inoperable non-small-cell lung cancer (NSCLC). A trial investigated the addition of atezolizumab with SBRT. Find out more: spkl.io/633227p08M #ERSCongress @europeanrespsoc.bsky.social

Physiotherapist-led care for musculoskeletal conditions in the emergency department (RESHAP-ED): a randomised controlled trial with economic evaluation spkl.io/633277pLCt

Peripheral arterial disease (PAD) affects more than 300 million people worldwide—yet it remains under-recognised, underdiagnosed, and undertreated. A new Editorial discusses a Lancet Series aiming to address this major health burden: spkl.io/633207pL2I

NEW in @thelancet.com—Physiotherapist-led care for musculoskeletal conditions in the emergency department (RESHAP-ED): a randomised controlled trial with economic evaluation www.thelancet.com/journals/lan... #MedSky #RheumSky #PhysioSky

In our latest issue, a study evaluates whether wealth redistribution policies can mitigate the health impact of the current official development assistance (ODA) defunding crisis. Read the study & explore the full issue: spkl.io/633257p2T3

Presented at #EASD2026—Mauritius is the first country to show a decreasing prevalence of diabetes and intermediate hyperglycaemia over time, using the objective, gold standard OGTT-based diagnostic criteria recommended by WHO. More in @thelancetendo.bsky.social: spkl.io/633217pvTl

🧵 GLP-1 receptor agonists (RA) are transforming diabetes and obesity. Women are the predominant users, but uptake has outpaced guidance. 2 papers in @lancetobgyn-wh.bsky.social explore GLP-1RA treatment in women: access, safety, & equity. #EASD2026 tinyurl.com/4h3852em

🌏Less than 5 days to go! Join @thelancet.com & DTH-Lab on 5 October for Unsafe by design? launching the new Lancet Series on the digital determinants of health. 📅 5 October 2026 | 13:00–14:30 BST / 14:00–15:30 CEST / Register now: scan qr / https://tr.ee/iY3uhd

New antibody treatment reduces number of new abnormal bone lesions by at least 90% in people with ultra-rare genetic disorder, fibrodysplasia ossificans progressiva (FOP), phase 3 study shows. Read now: spkl.io/633297T2st

Recent advances are redefining the understanding and management of hypoparathyroidism. In @thelancetendo.bsky.social, a Review summarises the scientific and medical findings presented at the Hypoparathyroidism 2025 Summit: spkl.io/633247puzI

Radiotherapy after surgery halves risk of recurrence in a type of brain tumour that can often grow back, trial shows. Find out more in The Lancet: spkl.io/633297TFyz #EANO2026 @eanoassociation.bsky.social

Our Clinical Resources hub is designed with clinicians in mind — clear, logical, and packed with the latest research. Discover how it can support your practice. spkl.io/633287rRiC

New @thelancet.com - Faecal microbiota transplantation in irritable bowel syndrome (REFIT2): a randomised, double-blind, placebo-controlled, phase 3 trial www.thelancet.com/journals/lan... #FMT #GastroSky #MedSky #MicroSky #IBS

📢 Just presented at #EANO2026 – and now published simultaneously in @thelancet.com! Results from the international multicentre randomised controlled ROAM/EORTC1308 trial, addressing radiotherapy vs. observation following surgical resection of atypical meningioma. 👉 www.thelancet.com/journals/lan...

Cancer genetic testing and precision oncology are advancing rapidly—but access is not. A new @thelancetoncol.bsky.social Commission sets out how health systems can scale these innovations equitably and sustainably: spkl.io/633287TYKi #WCC2026

Early-onset colorectal cancer (EO-CRC) is increasing globally. In The Lancet Regional Health - Eastern Mediterranean, authors assessed the burden, temporal trends, and future projections of EO-CRC across the WHO Eastern Mediterranean Region: spkl.io/633217TcwT