Jotham Suez (SuezLab@JHU)

New paper from the lab, out in Nature Microbiology. We ran CRISPRi screens to ask what genes E. coli needs in order to live in a gut and what this can tell us about the gut environment itself. https://doi.org/10.1038/s41564-026-02471-8

Twenty-two easy ways to power up your lab meetings | Nature by Hannah Docter-Loeb in Nature Careers Scientists share help and advice on how they got their research discussions flowing (including a contribution from our lab) www.nature.com/articles/d41...

In a small case series, combined phage therapy and faecal microbiota transplantation was safe and led to sustained reductions in recurrence, severity and antibiotic use in women with recurrent urinary tract infections, according to a paper in Nature Microbiology. go.nature.com/4gh0yyS #microsky 🧪

A new lab study suggests some sweeteners may affect gut bacteria. Jotham Suez, PhD, of Johns Hopkins, explains why human trials are needed to understand what this means for health. Read more in www.verywellhealth.com/common-sweet...

Exciting collaboration with @annabiosys.bsky.social's lab just went online. @isbscience.org metaSPLiT: a fast, efficient, and relatively low-cost method for single-cell transcriptomics in the human gut microbiome. 👇

🦠 The Skin Microbiome: From History to Therapeutic Frontiers From early microscopy to AI-driven microbiome engineering, skin microbiome research is transforming the future of dermatology. 📝: microbiomecongress.org/abstract-sub... #SkinMicrobiome #Microbiome #Dermatology #MicrobiomeResearch

📣 New Supplement publication in CMI The role of whole genome sequencing in antimicrobial susceptibility prediction of bacteria: 2025 update from the #EUCAST Subcommittee @escmid.bsky.social Read here: www.clinicalmicrobiologyandinfection.org/article/S119...

📢 We're hiring! The Department of Microbiology & Cell Biology at Montana State University is hiring an Assistant Professor of Microbiology. We welcome applicants working in microbial pathogenesis, immunology, genetics, microbial evolution, and related areas. Apply: jobs.montana.edu/postings/52009

Openings in cell and community synthetic biology at UW-Madison!! Some are at any level, so tell colleagues and yourselves. Information below, more to appear here & on campus sites soon. Great colleagues, facilities, place to live, succeed. What more could you ask for!! bact.wisc.edu/bacteriology...

As we kick off #PrideMonth, ASM proudly honors the achievements & contributions of 2SLGBTQIA+ scientists to the microbial sciences. Diverse identities, lived experiences & perspectives catalyze transformative scientific progress. Explore our resources: asm.social/2Xr

Cell Host & Microbe Focus Issue: The Virome www.cell.com/issue/S1931-... This focus issue offers a collection of articles that deliver cutting-edge insights and forward-looking perspectives on the virome's influence. @cp-cellhostmicrobe.bsky.social

Be sure to catch next week's episode featuring Dr. Samuel Nobs from @irbbellinzona.bsky.social! His research interests focus on the interplay between the microbiome and the lung immune system, in health and during disease. 🥼 Check out his research: https://go.nature.com/4a8YZzr

🚨Faculty job search: University of Illinois Chicago Micro & Immuno department is hiring! Open rank and open area within host-pathogen interactions. Apply by May 31 to join us in UI College of Medicine in the heart of Chicago! uic.csod.com/ux/ats/caree...

A new method for inference and tracking the transmission of strains in metagenomes #MicroSky #MicroEco www.nature.com/articles/s41...

Out Now! Unravelling bacterial complexity at high resolution with single-cell transcriptomics #MicroSky

If you’re at #DDW2026, come say hi! Started the meeting strong co-moderating a session with Long Nguyen, a full room came at 8AM to listen to Gautam Dantas, David Underhill & Megan Baldridge sharing exciting unpublished data on gut phages 🦠 fungi 🍄 & eukaryotic RNA viruses 🤩

Check out science writer Ed Cara's @edcara.bsky.social piece 'Should We Finally Ditch Artificial Sweeteners?' Ed talks to @johnshopkinssph.bsky.social & @jhu.edu molecular microbiologist & microbiome expert Jotham Suez @suez.bsky.social gizmodo.com/should-we-fi...

Phage community: our plasmids for executing phage transposon mutagenesis are now on AddGene and I would love for you to try it out! It is powerful for ID'ing all essential genes and knocking out all non-essentials in a single experiment :) New exp here: www.addgene.org/browse/artic...

Have you developed a new #bioinformatics tool to understand #phage or #virus? Make sure you add it to #awesome-virome github.com/shandley/awe...

We are proud to again be recognized by our peer schools and programs as the #1 public health school in the nation, as reported by U.S. News & World Report. The Bloomberg School is grateful to partner closely with our peers on our shared commitment to improving health for people everywhere.

ICYMI: New online! Diet–microbiome associations

Microbes impact peanut allergy Mouth & gut contain peanut-degrading bacteria(Rothia) that metabolize PN allergens. Mice colonized w/Rothia show decreased anaphylaxis & allergic patients w/better PN tolerance have higher abundance of these bacteria www.cell.com/cell-host-mi...

Katalin Karikó will be @jhu.edu's 2026 commencement speaker. Excellent choice! www.jhunewsletter.com/article/2026...

Female urogenital microbiome: Review by Sarah Lebeer & Co In urogenital tract, dominant lactobacilli shape vaginal immunity & community stability. Review examines molecular strategies & rational design of next-generation microbiome-based therapies www.cell.com/cell-host-mi...

Gut microbes sound the alarm during sleep loss Leone et al. find short-term sleep loss in healthy humans alters 24-hr rhythmic profiles of circulating microbially derived metabolites, including butyric acid & tryptophan catabolites, relative to habitual sleep: doi.org/10.1172/JCI1...

New paper in mSystems! 🧵 - how much of your metagenome is actually bacterial/archaeal DNA? For many samples, nobody knows. We built SingleM prokaryotic_fraction (SPF) to answer this, then ran it on >100,000 public metagenomes. 🧬🖥️🦠 Here's what we found 👇 doi.org/10.1128/msystems.01062-25

🚨 A new piece of the preterm gut microbiome puzzle just fell into place! Bifidobacterium metabolise human milk oligosaccharides (HMOs) in early life — shaping immunity, supporting gut development, and protecting against diseases like necrotising enterocolitis (NEC). www.nature.com/articles/s41...

Our new study shows that a human-derived Bacteroides salyersiae can reverse depressive-like behavior in a chronic stress model, with effects comparable to ketamine. The talented @philstrandwitz.bsky.social to creating microbiome-based antidepressant therapeutics. link.springer.com/article/10.1...

A single course of antibiotics can have lasting effects on your gut microbiome, with changes that last well beyond 4 years. Three types of antibiotics stood out for their long term disruptive impact (3 at left, Figure) nature.com/articles/s41...

Out today: We discovered new viral proteins that target immune signaling molecules, solely based on their AlphaFold-predicted shapes www.science.org/doi/10.1126/... Congrats Nitzan Tal and coauthors! Thank you Kranzusch lab for the fun collaboration! Linking below previous thread on our findings

"Can you trust the results from gut microbiome tests? Maybe not." www.sciencenews.org/article/resu... I understand why the authors didn't disclose the different company IDs...but I'm very curious to know which is which

Our latest is out today in @plosbiology.org: "Metabolic modeling reveals determinants of prebiotic and probiotic treatment efficacy across multiple human intervention trials" @isbscience.org @uwbioe.bsky.social @uwgenome.bsky.social doi.org/10.1371/jour...

In this report from Singapore, the release of wolbachia-infected, irradiated male 𝘈𝘦𝘥𝘦𝘴 𝘢𝘦𝘨𝘺𝘱𝘵𝘪 mosquitoes resulted in a reduction in the vector population and in the risk of dengue infection. Full report: nej.md/4atd2iN #MedSky #IDSky

#NatMicroPicks FMT for cancers in clinic! 💩🦠🦀⚕️ Three different clinical trials report activity of faecal microbiota transplant against cancer #MicroSky #CancerSky www.nature.com/articles/s41... www.nature.com/articles/s41...

Jothan Suez, PhD, @suez.bsky.social, who studies sweeteners @jhu.edu @johnshopkinssph.bsky.social, comments on @wsj.com article www.wsj.com/health/new-d...

Super excited to share my latest publication with Justin Malogan and @suez.bsky.social , my love letter to viromics! 🦠 Here, we discuss computational and wet lab methods to study the gut virome and how they can be used together But why is this synergy so important? journals.asm.org/doi/10.1128/...

🦠 How do microbes arrive together, and why does it matter for #microbial #diversity? 👉 Read the paper: journals.plos.org/ploscompbiol... Published in @plos.org Computational Biology 🎉 Congratulations to authors Loïc Marrec & Sonja Lehtinen @sonjalehtinen.bsky.social @unil.bsky.social @sib.swiss

Our new paper, where we use metabolic modeling to show Fusobacterium grows faster in colorectal tumor vs normal tissue microenvironments, and use computational + experimental approach to find specific metabolic pathways driving host-microbiome interactions in cancer www.biorxiv.org/content/10.6...

A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers. buff.ly/K7CGFLV

We're at 735 registrants and counting! 🎉🦠 If you haven't registered yet, don't miss out on this exciting (free) symposium on gut microbial metabolites and their impacts on host health. Please share with your networks. 🔗👇 isbscience.org/events/2025-...

Campus friends @ Homewood