Michael Hothorn

Out in @natplants.nature.com, mapping of brassinosteroid chemical features required for (1) receptor binding, (2) ligand positioning and (3) co-receptor recruitment. Fantastic work by Alberto Caregnato & @hmchen93.bsky.social and our friends in Olomouc. Funding:@snf-fns.ch -> doi.org/10.1038/s414...

Join us in Halle for our #SNP2Prot international conference 2027 - Registration is open as of today!

Das war ruhig und argumentativ fundiert diskutiert, tolle Leistung!

Today’s department seminar by @pascalalbanese.bsky.social @cea.fr Grenoble on protein - protein interactions in photosynthetic complexes

„Without funding of basic research – which is the advantage of doing research in Germany – our discoveries would not have been possible”, Nobel Prize laureate 2026 Peter Hagemann points out in German news @heutejournal.bsky.social (starting at 19:00 minutes) – in German www.zdf.de/play/magazin...

Peter Hegemann and Georg Nagel – awarded the 2026 medicine prize – discovered a remarkable protein, channelrhodopsin, in a single-celled alga. Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.

BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”

Synthetic FLS2 receptor oligomer boosts plant innate immunity | Science Advances www.science.org/doi/10.1126/...

🌿 Another recent article by @cellsensing.bsky.social @fbm-unil.bsky.social @unil.bsky.social published in @natplants.nature.com 👏 👏 👏 Congratulations to all the authors 🔗 www.nature.com/articles/s41...

🧵 1/8 Have you ever wondered how information embedded within exons regulates gene expression in plants? 🌱🧬 Check out our latest work, where we explore how exonic enhancers (EEs) shape gene expression in plants! www.biorxiv.org/content/10.6...

We’re looking for a new colleague in Würzburg! 🌱 W3 Professorship in Plant Metabolism 💊 Chair of Pharmaceutical Biology 🧪 Head of the Metabolomics Core Unit jobs.zeit.de/jobs/univers... Please spread the word! Questions? Feel free to contact me. www.biologie.uni-wuerzburg.de/en/about-the...

www.biorxiv.org/content/10.6... If you thought plant gene refulauwas simple… Cool work from Christian Hardtke, Noel Blanco and teams on exonic enhancers!

Congratulations Martin!!!

ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi...

Anthropic has used Claude to optimise structure prediction and design code to improve speed and memory efficiency. 2-3X speed improvements on AF3, 5X on OF3, 5X on BindCraft low memory modes to model large assemblies. All released as open source www.anthropic.com/research/cla...

21627 applications. Nothing to celebrate here. Impossible to evaluate fairly & safely. Neither the science (too diverse & possibly LLM generated) nor the soft criteria (likely LLM generated). Without an interview stage - a security risk! marie-sklodowska-curie-actions.ec.europa.eu/whats-new/ne...

There is "thinking outside the box", and then there is "thinking outside the boxer". Nice work from @agroscope.bsky.social nph.onlinelibrary.wiley.com/doi/10.1002/...

"How SCREW finds its NUT" rdcu.be/k8vBj18vix9a A News & Views on 3 complementary structural studies published together about SCREW/CTNIP–NUT/HSL3 signalling: rdcu.be/AY11kgcFgTia rdcu.be/S6g7YM6WPjTa rdcu.be/16bsh4fYzpna

A PPNT-motif containing effector inactivates BIN2, with interesting phenotypic consequences. Nice study by @effectomics.bsky.social www.biorxiv.org/content/10.6...

Transcriptional activation of plant immunity by salicylic acid www.nature.com/articles/s41...

ColabFold 1.6.3 is out! 2.5x faster, pip-installable, ipSAE+pDockQ2 scores. Thanks Choonghwan Lee, Marielle Russo, Gyuri Kim 🐍pip install colabfold[alphafold] CF2 Sneak Peak with AF3/Boltz/Protenix/ESMFold2… 🐍pip install "colabfold[alphafold3]@git+https://github.com/sokrypton/ColabFold@af3-preview"

The PhD and Postdoc application links are now live! Come join me at UNIL to work on deep learning for protein structure, interactions & design. pickybinders.org#open-positions

A redox-regulated RCC1-like protein controls catalase activity in Arabidopsis 🌱 by Zhoubo Hu et al. @zhoubo1234.bsky.social, @biology-unige.bsky.social - published final version now available, open access @natcomms.nature.com www.nature.com/articles/s41... rdcu.be/fQjnjegEfrua

The LRR crystallization screen described here enabled structure determination of the Arabidopsis receptor kinase SRF6 ectodomain #CrystallizationScreens #LeucineRichRepeats #Ectodomains doi.org/10.1107/S205...

PPRM2026 ( Plant Peptide Receptor Meeting) starts tomorrow : this time in Freising, Germany 🇩🇪 with an excellent scientific program! Looking forward!

At Peptide Receptor Meeting #PPRM2026. A theme that came back twice is re-evaluation of old published results. We know about ABP1 and the systemin receptor, but there were two other examples today: WAK1 perception of OGs, and BSU1 Tyr dephosphorylation of BIN2 in BR signalling. #PlantScience

Next on @structplantbio.bsky.social invites us to re think brassinosteroid signaling #PPRM2026

Nice work by @cellsensing.bsky.social Glycan recognition by a plant damage-sensing immune receptor www.science.org/doi/10.1126/...

Very interesting perspective piece from @christianhardtke.bsky.social on plant cell axis formation and on a time period when basic research was not consumed with plastic forks and spoons. link.springer.com/article/10.1...

If you're looking for a REALLY active protein kinase, they found one. Crazy stuff www.nature.com/articles/s41...

Come be my colleague! We are hiring a structural biologist. I have thoroughly enjoyed starting my career here and both department(s) are full of exceptional scientists. apol-recruit.ucsd.edu/JPF04589

A redox-regulated RCC1-like protein controls catalase activity in Arabidopsis 🌱 - accepted manuscript by Zhoubo Hu @zhoubo1234.bsky.social et al now online @natcomms.nature.com, with @vanbreusegemlab.bsky.social @amnamhamdi.bsky.social @grandpahiro.bsky.social @sara-stolze.bsky.social

Interested in the Function and Regulation of #T6SS? Do you have relevant experience from your Master's project? Apply to this PhD position in our lab: www.biozentrum.unibas.ch/open-positio...

A major advice I try to pass on: science is only worth it if you can delight in the discoveries of others. It’s great to make your own discoveries but they are too few to sustain you over the long haul.

August issue is out! journals.iucr.org/d/issues/202... The cover highlights SURFER, a lightweight GPU-accelerated extension for UCSF ChimeraX that enables rapid semantic differentiation of membrane or membrane-mimic density from macromolecular signal in cryo-EM maps. More at doi.org/10.1107/S205...

🚨safe the date🚨 our SNP2Prot SFB @snp2prot.bsky.social @unihalle.bsky.social will host an international conference next summer (June 21st-23rd 2027) with a fantastic line-up of international experts. Registration opens October 17th.

check out our latest review. Beyond prediction: Why experimental structural biology remains essential in plants. www.sciencedirect.com/science/arti...

It seems to me that the focus of this study is on drivers rather than pedestrians?

Privateer for UCSF ChimeraX: Carbohydrate structure validation and visualization pubmed.ncbi.nlm.nih.gov/42427255/ #cryoEM

Please share! 🌱🤖 Permanent W2 Professorship in crop & plant sciences @ PhenoRob, University of Bonn. Especially encouraged: crop genome engineering, sustainable pest control, or sustainable disease control. Expertise in one area is enough. Apply by Sept. 30, 2026. www.uni-bonn.de/en/universit...

Nature Communications is looking for a plant biology editor: springernature.wd3.myworkdayjobs.com/SpringerNatu...

Our lab @mpi-mp-potsdam.bsky.social is hiring two postdoctoral researchers to join our ERC-funded GRAFT project on mobile small RNAs in plants. 🔗 Details: jobs.mpimp-golm.mpg.de/jobposting/b... 📅 Deadline: July 31, 2026 Please share!

That’s settled then 😂