Sten Linnarsson

progress.openai.com

A little over two weeks to the deadline! 20 positions, generous startup funding, a great community and fantastic infrastructure. Come join us!

”All contracts with Springer Nature are terminated or no longer active. Precious taxpayer dollars should be [sic] not be used on unused subscriptions to junk science.” the NIH spokesperson said. www.nature.com/articles/d41...

We're looking for a new Assistant Professor in Experimental Tumor Biology to join us at Karolinska Institutet (MTC) @ki.se . Generous funding package and part of a 20 Assistant Prof recruitment in a wide range of subject areas. 📅 Deadline: Sep 2nd, 2025 ki.varbi.com/en/what:job/...

1/3 I spent 10 years running a lab in Philadelphia and then decided to return to Europe and continue in a more family friendly environment. Best decision of my life! You can now do the same by applying to one of these 20 assistant professor positions at Karolinska Institutet ki.se/en/about-ki/...

Come join our department at the Karolinska Institute! ki.varbi.com/what:job/job...

The call just opened! ki.se/en/about-ki/... You can apply to several departments simultaneously, check out which depts better fit your profile! Here is the call for our Department of Medical Biochemistry and Biophysics ki.varbi.com/what:job/job...

In these turbulent times, beautiful microscopy always cheers me up 😍. Here's a quail neural tube just doing its thing for #FluorescenceFriday. Imaged by the very talented @vanderspuy.bsky.social #devbio 🧪🔬👩‍🔬

🚨NEW - In vivo CAR T cell generation to treat cancer and autoimmune disease @capstantx.bsky.social direct delivery of mRNA-encoded CARs to CD8+ T cells in mouse & NHP models shows tumor control not only in blood, but also tissue. Immune reset seen at B cell recovery www.science.org/doi/10.1126/...

Heads-up for major new faculty search at KI — with great startup packages and a wide range of subject areas.

Very cool work from James Zou. Link to paper: www.nature.com/articles/s41...

⚡️Really thrilled that #textgrad is published in @nature.com today!⚡️ We present a general method for genAI to self-improve via our new *calculus of text*. We show how this optimizes agents🤖, molecules🧬, code🖥️, treatments💊, non-differentiable systems🤯 + more!

Choose Science. Choose Europe. A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open. With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond. Apply by 10 September → europa.eu/!fBTMgF

Discover aptamers faster! UltraSelex combines partitioning, high-throughput sequencing & computation in 1 step. Revolutionize drug discovery! PMID:40164941, Nat Chem Biol 2025, @nchembio https://doi.org/10.1038/s41589-025-01868-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

New paper out in @pnas.org We followed cells migrating along signalling gradients in 3D, and found they collectively behave as a living droplet - a self-propelling fluid that grows. www.pnas.org/doi/10.1073/...

Intratumoral cDC1-T Cell Clusters Serve as Sites of Local Costimulation to Enhance CTL-Mediated Tumor Rejection https://www.biorxiv.org/content/10.1101/2025.05.19.654765v1

www.science.org/doi/10.1126/...

How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵

1/10 Our latest research, led by @martijnselten.bsky.social, identifies a mechanism through which Parvalbumin (PV) interneurons regulate their activity in the #cortex. This is the story @nature.com www.nature.com/articles/s41... ⬇︎ 🧵 @devneuro.bsky.social @kingsioppn.bsky.social @erc.europa.eu

Some exciting #PainResearch / #Neuroskyence from @alexchesler.bsky.social & co!

🚀 New publication! We developed a PTPRZ1-specific TCR-T cell therapy for glioblastoma. 🔬 Key findings: ✅ Identified a PTPRZ1-reactive TCR from a vaccinated patient ✅ Kills glioblastoma cells with no off-target effects ✅ Eliminates tumors in murine brain models 🔗 www.nature.com/articles/s41...

What if LLMs could “read” & “write” biology? 🤔 Introducing C2S‑Scale—a Yale and Google collab: we scaled LLMs (up to 27B!) to analyze & generate single‑cell data 🧬 ➡️ 📝 🔗 Blog: research.google/blog/teachin... 🔗 Preprint: biorxiv.org/content/10.1...

Are you an established (”distinguished”) researcher outside Europe? Thinking of moving here for some reason? Grant opportunity just dropped: www.vr.se/english/appl...

We're looking to hire a research assistant for flow cytometry of brain tumor immune cells! Apply here -> ki.varbi.com/en/what:job/...

Join us for a Research Lecture by @michellemonje.bsky.social at the Nobel Forum @ki.se, this Friday 7th March at 1pm! www.nobelprizemedicine.org/research-lec...

Two exciting 🆕 studies reveal insights into cell type specificity in #schizophrenia & depressive disorders. By leveraging existing genome-wide association studies ( #GWAS ), both identified key brain cells & regions that may offer the most promising targets for treatment. 🧠 🧪

”Cancer is a rebellion—a gangster outbreak of misplaced cells”.