Stem Cell Podcast

🔔 The second episode has dropped! In partnership with the @isscr.org Early Career Advisory Committee, we're spotlighting rising leaders in stem cell research. Hear from Drs. @anupamahl.bsky.social and Verena Schwach on cell fate and #cardiac development! 🎧 Tune in: https://bit.ly/4zmw4T2

📢 The second episode of our new quarterly series drops next week! In partnership with the @isscr.org's Early Career Advisory Committee, we hosted Drs. Anupama Hemalatha and Verena Schwach. Don't miss it! Dr. Hemalatha's work: https://go.nature.com/4shj3Yj Dr. Schwach's work: https://bit.ly/4zB2RUm

🎉 We have a winner! Congratulations to our Speaker Giveaway winner, Dr. Jessy Alexander at @ubuffalo.bsky.social! A big thank you to everyone who participated. Stay tuned for more exciting opportunities! 👏

🔔 Tune into this special live recording at the @alleninstitute.org with Drs. Crystal Rogers (@rogerslabucd.bsky.social) and Ariel Waisman (@waisman-ar.bsky.social) where they share their journey of navigating early-career hurdles and adapting to lab leadership. Listen now: https://bit.ly/47mVcwO

🎙️Next week, we drop a special live recording from the @alleninstitute.org! We invited two guests to discuss realities they face as early career researchers. Dr. Crystal Rogers (@rogerslabucd.bsky.social): https://bit.ly/46Lny3u Dr. Ariel Waisman (@waisman-ar.bsky.social): https://bit.ly/4hNKlBS

📣 The next episode is out! Tune into our conversation with Dr. Lika Drakhlis at Hannover Medical School to learn all about how her lab uses hPSCs to develop complex, multi-tissue #organoids that model the co-development of the heart, vasculature, and foregut. 🧫 Listen now: bit.ly/47euMgv

This first-in-human trial led by Jose Moraleda and Luis Linares shows that bone-targeted mesenchymal stem cells can promote bone formation and reduce fractures in #osteoporosis. 🦴 More on the study: https://bit.ly/4rlTipc 🎙️ Tune into the discussion: https://bit.ly/47euMgv

Scientists with Rayyan Jokhai and Dr. Kyle Loj at @stanford.edu utilized lineage tracing and stem cell models to reveal two distinct neural progenitors that separately give rise to the forebrain/midbrain and hindbrain. 🧠 🧪 https://go.nature.com/4xE7oUo 🎧 https://bit.ly/47euMgv

Self-organizing neural organoids recreate the coordinated development of the spinal cord and peripheral sensory nervous system, enabling studies of development, disease, and drug effects. 🧫 More on the study: https://bit.ly/3VMIpB2 🎧 Listen now: https://bit.ly/47euMgv

Dr. @sergiuppasca.bsky.social's lab with Konstantin Kaganovsky, @kevinkelley.bsky.social, Tilo Gschwind, and Paul Harary integrated human cortical organoids into mice, forming functional neural circuits. 🧠 🧫 https://go.nature.com/4yegEQt Tune in: https://bit.ly/47euMgv

🔔 Stay tuned for next week's episode featuring Dr. Lika Drakhlis at Hannover Medical School! The Drakhlis lab focuses on hPSC-derived heart-forming #organoids, which model heart, vasculature and foregut co-development. 💓 Check out their latest work: https://go.nature.com/4y98zfY

The Hippo–IGF2 signaling pathway was found to control organ growth and liver #regeneration, with IGF2 restoring impaired regenerative capacity in aged mice. 🐁 Read more: https://bit.ly/4iW1JW3 🎧 Tune into the discussion: https://bit.ly/4xGNSaO

Jian Li and investigators at @harvardmed.bsky.social found that loss of ALDH3B2 converts human pancreatic duct cells into #insulin-producing β-like cells capable of improving blood glucose in diabetic mice. 🩸 More on the study: https://bit.ly/4gOALNr 🎧 Listen now: https://bit.ly/4xGNSaO

Scientists with Dr. Lingling Hu at @weillcornell.bsky.social identified tendon/ligament #StemCells and showed that their abnormal differentiation contributes to ligament thickening and lumbar spinal stenosis. 🦴 More on the study: https://bit.ly/4AalW0Q 🎧 Tune in: https://bit.ly/4xGNSaO

🎧 The next episode is live! Dr. Yonatan Stelzer at @weizmann.ac.il discusses how his lab combines developmental biology, epigenetics, and single-cell technologies to understand how cells acquire distinct identities during #embryonic development. 🧬 Listen now! https://bit.ly/4xGNSaO

🤩 Hope you're excited for our next guest, Dr. Yonatan Stelzer at @weizmann.ac.il! The Stelzer Lab investigates how cell fate and identity are established during #embryonic development using single-cell and epigenomic approaches. 🧫 Check out his latest work: https://bit.ly/3UsGAsB

Scientists with @katecavanaugh.bsky.social in the Weiner Lab at UCSF found that reproductive aging increases #embryo contractility and alters tissue mechanics, reducing successful embryo implantation.🫄 Here's the study: https://go.nature.com/4gmQ01l 🎧 Listen now! https://bit.ly/4wV6VNv

Researchers discovered that generating tetraploid iPSCs produces #cardiomyocytes with more mature molecular, metabolic, and functional properties than conventional iPSC-derived cardiomyocytes. 💓 🧫 Check out the study: https://go.nature.com/4hSuYc4 🎙️ Listen now! https://bit.ly/4wV6VNv

Dr. Georgina Craig and scientists at @unityhealthto.bsky.social found that changes in oligodendrocytes and reduced NRF2 signaling are linked to cognitive decline during #aging, identifying a potential therapeutic target. ⏳ 🧪 https://go.nature.com/4wU1qyE Tune in: https://bit.ly/4wV6VNv

Dr. Irene Faravelli, Noelia Antón-Bolaños, and scientists in Dr. Paola Arlotta's lab at @harvard.edu found that human brain #organoids cultured for five years continue to mature and retain a molecular memory of time spent in culture. 🧠 🔬 https://go.nature.com/4zIkDWC Tune in: https://bit.ly/4wV6VNv

🔔 The next episode has dropped! Dr. Charles Easley at @universityofga.bsky.social discusses how his lab uses #PSCs and in vitro models of #spermatogenesis to investigate how environmental exposures affect male fertility. Tune in now! https://bit.ly/4wV6VNv

Stay tuned for next week's guest! Dr. Charles Easley at @universityofga.bsky.social join us to talk about his research using stem cells to study male fertility and develop new therapies. #spermatogenesis Check out their work: https://bit.ly/4gM6QXv

Dr. Holly Vogues' team at The Royal Children's Hospital Melbourne found that stem cell-derived 3D heart valve tissues recapitulate key features of valve maturation, providing a platform for studying inflammation and calcific valve disease. 🔬 https://bit.ly/4zlUlJo 🎧 Tune in: https://bit.ly/4xRQmD3

Dr. Guang Li's lab with Yuanhang He at @pittdeptofmed.bsky.social developed hiPSC-derived valve #assembloids that model heart valve development and reveals how mechanical forces and fluid flow shape valve formation and disease. 🧪 https://bit.ly/45ykY0g Tune in: https://bit.ly/4xRQmD3

Researchers with Dr. Carmen Herranz-Ors at @sangerinstitute.bsky.social developed a collection of patient-derived tumor #organoids that maps genetic dependencies and therapeutic vulnerabilities across multiple cancer types. 🔬 https://go.nature.com/4xGZ8U5 Tune in: https://bit.ly/4xRQmD3

New preprint from the lab is out! Dll4 and Jag1a aren't opposing Notch signals in blood stem cell formation — they are required sequentially to push hemogenic endothelium fate and to make HSPCs . Great collab with @gunawanlab.bsky.social @dorotheeb.bsky.social 🔗 www.biorxiv.org/content/10.6...

Dr. Magdalena Sutcliffe and team at @cambridgebiocampus.bsky.social discovered a chemical chromatin restoration approach that reverses differentiation defects in hPSCs, restoring their ability to generate brain #organoids. 📃 https://go.nature.com/4qhwOW8 Listen now: https://bit.ly/4xRQmD3

📢 The next episode is out! Join us with Dr. Abdullah Khan at @ox.ac.uk as we talk about how his lab engineers complex human tissue models to study the cellular interactions that drive development, aging, and disease. 🎧 Listen now! https://bit.ly/4gjgj7p

🥼 Introducing our next guest! Dr. Abdullah Khan from @ox.ac.uk will be joining us on the podcast to talk about his research on engineering complex human tissue models to study cell interactions, aging, and disease. 🔬 His latest work: https://bit.ly/3P7lZan

Dr. Janice Reid and scientists at QIMR Berghofer Medical Research Institute reveal a comprehensive atlas of human #CardiacOrganoids that shows how signaling molecules regulate heart function and identifies pathways linked to heart failure. 💓 📃 https://bit.ly/4xfFCy3 Tune in: https://bit.ly/3TCds1C

Scientists found that long-term vitamin C supplementation partially reverses age-related changes in primate bone marrow and hematopoietic stem cell function. 🍊 Here's the study: https://bit.ly/455UMK8 Tune in: https://bit.ly/3TCds1C

Scientists at Huazhong University of Science and Technology found that intestinal stem cells use an #epigenetic division-counting mechanism to precisely control cell fate decisions during tissue maintenance. 🧬 Read more: https://go.nature.com/4fUTQxe Listen now: https://bit.ly/3TCds1C

Researchers with Evan Appleton at Colossal Biosciences have generated the first #iPSCs from Asian elephants, providing a new platform for conservation and disease research. 🐘 Read more: https://go.nature.com/4y2YAc8 Listen to the discussion: https://bit.ly/3TCds1C

📢 We're honored to welcome Nobel Laureate Dr. Shinya Yamanaka! Join us as we explore the story behind one of the most transformative discoveries in modern biology and discuss the future of stem cell research with the pioneer of #iPSC technology. 🎧 Listen and share! https://bit.ly/4yXJZiS

🚨 Something big is coming! 20 years after the discovery of #iPSCs, we're sitting down with the scientist behind it all. Dr. Shinya Yamanaka, @nobelprize.org Laureate, joins us to discuss the discovery that changed regenerative medicine and where we're headed next. 📃 https://bit.ly/4vQnpFX

We've got a special episode for you! Drs. Michael May and Janet Rothberg from CCRM discuss scaling and manufacturing of PSC-dervied therapies in front of a live audience at #ISSCR2026. 🎧 Listen now: https://bit.ly/4vF6NBe

Researchers led by Dr. Timothée Mouterde, Adam Hill, and Hoang-Phuong Phan have developed a wireless cantilever platform that enables high-throughput measurement of contractile forces in human cardiac organoids. 🗒️: https://go.nature.com/4f3DaTE 🎧: https://bit.ly/4f5dXIC

That’s a wrap on #ISSCR2026! 🎊 Thank you to everyone who joined us. From listeners to guests to organizers to the incredible stem cell community, we're so grateful for the great conversations, science, and energy all week long. 🧡

Looking for something to listen to on the way home from #ISSCR2026? Our final daily episode is out now! Catch up on the research presented on the final day of the meeting: https://bit.ly/3SRKIBH

We have a new episode out! Daylon and Arun summarize the research presented yesterday at #ISSCR2026. 🎧 Listen now: https://bit.ly/4wH7cnC

Thank you to everyone who joined us for our "On the Ground" #ISSCR2026 episode! Hear what they had to say when the episode airs on July 21st!

Our Day 2 #ISSCR2026 episode is out now! 🎧 Listen to catch up on yesterday's talks: bit.ly/4eXagpE

Congratulations to Haewon Cho from Seoul Women’s University on winning our gift basket! 🎉 If you're at #ISSCR2026, there's still time to stop by the Stem Cell Podcast booth! Come say hi! 👋

📣 Happening now! We're recording in Room 515a until 3:30 pm. Drop by for a ten-minute Q&A with Daylon and Arun and you could appear on an episode of the Stem Cell Podcast! #ISSCR2026

Using patient-derived organoids, researchers in the lab of Dr. Dannielle Engle at the @salkinstitute.bsky.social have identified chronic #pancreatitis subtypes and revealed CFTR modulators as a potential therapeutic strategy. 📘: https://bit.ly/4ww3oFv 🎧: https://bit.ly/4f5dXIC

We'll be recording today at #ISSCR2026, and you could be our special guest! Sign up at booth #207 to be on an episode of the podcast! 🎙️

What a day! 🤯 Catch up on all the excitement from yesterday's sessions at #ISSCR2026: https://bit.ly/3SRPe32

Arun is a skeletal muscle cell! What is your cell fate? Stop by booth #207 at #ISSCR2026 to find out and snag matching pins!

Today is your last chance to win a gift basket at #ISSCR2026! 🎁 Visit booth 207 to enter!

New work from the lab of Dr. Norihiro Goto at @weillcornell.bsky.social suggests that loss of GATA6 promotes #ColorectalCancer liver metastasis by driving multilineage cellular plasticity. 1️⃣ Read the study: https://bit.ly/4oI65kN 2️⃣ Listen to the episode: https://bit.ly/4f5dXIC