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Join us! With a fully funded PhD scholarship. www.linkedin.com/feed/update/... @saigenci.bsky.social
Stefano Mangiola
@stemang.bsky.social
Computational cancer-immunology and tumour microenvironment @SAiGENCI and @WEHI_research, VCA fellow @VicGovDH
1.8K followers25 following66 posts
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Join us! With a fully funded PhD scholarship. www.linkedin.com/feed/update/... @saigenci.bsky.social
Only one more week to apply for the #BiocAsia Travel Scholarship, to join us at #BiocAsia2026 and #ABACBS2026. Don't miss the opportunity! Please share with your peers who might be interested. π @bioconductor.bsky.social @abacbs.bsky.social
Great news! @saigenci.bsky.social, through its Computational System Oncology Program, is a main supporter of #BiocAsia2026! With their support, we will be able to provide travel scholarships; news soon! @bioconductor.bsky.social @abacbs.bsky.social
Great news! @saigenci.bsky.social, through its Computational System Oncology Program, is a main supporter of #BiocAsia2026! With their support, we will be able to provide travel scholarships; news soon! @bioconductor.bsky.social @abacbs.bsky.social
You still have time to submit your workshop!
π£ Call for Workshop Proposals: BioCAsia 2026 BioCAsia 2026 will take place on 19-20 November 2026 in Melbourne, Australia, and the call for workshop proposals is now open. ποΈ Submission deadline: 21 August 2026 π www.abacbs.org/workshops-20... #BioCAsia #Bioconductor
Join us! With a fully funded PhD scholarship. www.linkedin.com/feed/update/... @saigenci.bsky.social
π’ π Finetuning masking challenges narrow-task evaluation of cell foundation models shorturl.at/dcz3l We tested foundation model architectures across extreme reductions in pretraining scale. We found that standard narrow tasks were insensitive to pretraining scale, up tp 128-fold reduction!
π€ We hope these results motivate the community to rethink narrow-task benchmarking and narrow-task applications, and to pivot towards open-ended biological inference in zero-shot settings. @saigenci.bsky.social
First #tidyomics hackathon at #EuroBioC2026 in Turku! tidyomics.github.io/tidyomicsBlo... Join us at Euro Bioc (eurobioc2026.bioconductor.org) for a dive into our ecosystem, where you can learn about it and, hands-on, improve and extend it. Plz share! π @bioconductor.bsky.social
New #tidyomics blog post! π #tidySummarizedExperiment greatly simplifies your omics workflows, giving tidyverse capabilities. We have improved its performance 30x on large datasets with tens of thousands of samples! tidyomics.github.io/tidyomicsBlo... Plz share! @mpibiochem.bsky.social
Stefano Mangiola reposted
Replying to @mikelove.bsky.social
Another Bioc 3.23 update: new dplyr function support for a number of tidyomics packages @stemang.bsky.social Adding slice_sample, *_head, *_tail, *_min, and *_max to: - tidySingleCellExperiment - tidySeurat - plyranges The dplyr descriptions for these: dplyr.tidyverse.org/reference/sl...
#cellNexus is out! -> "Quality control, annotation, aggregation and analytical layers for the Human Cell Atlas data" - QC layers - Consensus cell annotation layers - Pseudobulk aggregation of the whole human atlas - R/Python APIs cellNexus.org Preprint: www.biorxiv.org/content/10.6...
This work started as an internal resource and has now become public with helpful APIs. It was 3+ years in the making, with a massive Thanks to Mengyuan Shen and the whole Team! We hope you find it useful π @saigenci.bsky.social @wehi-research.bsky.social @bioconductor.bsky.social
Reproducibility is key to science. In computational biology, we routinely manipulate high-dimensional data (spatial, single-cell, bulk) through filtering, normalisation and transformation. Capturing those steps clearly improves reproducibility and transparency. tidyomics.github.io/tidyomicsBlo...
Juan Henao has published a post on the #tidyomics blog introducing *omicslog*, which tracks and stores data manipulation directly from tidy R (and base R) workflows, in the data object itself! Inspired by `tidylog`. Feedback welcome! @bioconductor.bsky.social
A great last #tidyomics meeting of the year, looking forward to more of these in 2026! @bioconductor.bsky.social
The last #tidyomics meeting of the year is in 2 days. Everyone welcome! - 16 Dec, 3:30 pm (EST; New York) - 16 Dec, 9:30 pm (CET; Berlin) - 17 Dec, 7:30 am (AEDT; Melbourne) We will chat about plans for next year. Zoom link: shorturl.at/Epbbc @mikelove.bsky.social @bioconductor.bsky.social
The last #tidyomics meeting of the year is in 2 days. Everyone welcome! - 16 Dec, 3:30 pm (EST; New York) - 16 Dec, 9:30 pm (CET; Berlin) - 17 Dec, 7:30 am (AEDT; Melbourne) We will chat about plans for next year. Zoom link: shorturl.at/Epbbc @mikelove.bsky.social @bioconductor.bsky.social
Great first #tidyomics meeting, covering 3 continents! π We discussed data representation with #tidyprint. Stay tuned for the next one to discuss workshop delivery, education and more! Join the slack channel #tidiness_in_bioc community-bioc.slack.com/archives/CEQ... @bioconductor.bsky.social
It's official! The #tidyomics blog is up! π Here, the introductory post tidyomics.github.io/tidyomicsBlo... This blog aims to publish not only news about our community but also anything related to tidy interfaces, opinions, events, and more. Plz share! π @bioconductor.bsky.social #rstats
Amazing event! It is good to see the Adelaide community coming together! #ABACBS2025
Thatβs a wrap! Huge thank you to everyone who joined us for #ABACBS2025 & a big shout-out to the Adelaide bioinfo community who worked their butts off. Couldnβt have asked for a better crew or a better venue than Adelaide Oval. @wessidepraxis.bsky.social @linsalrob.bsky.social
Well done, William Hutchison! For an amazing talk about prostate cancer tumour microenvironment at #ABACBS2025 Also, well done on a great workshop on #tidyomics and his #tidySpatialExperiment @bioconductor.bsky.social
Registrations for the @abacbs.bsky.social and @bioconductor.bsky.social #BiocAsia workshops close TOMORROW at 5PM! Don't miss the opportunity to learn the new trends in computational biology!
ABACBS/BioC Asia 2025 Workshops are coming! @ Adelaide 27-28 November. Join us in November for two days of deep-dive sessions on scalable bioinformatics, spatial omics, AI-driven genomics, and more blackochrelabs.au/abacbs2025_w... #Bioinformatics @abacbs.bsky.social @bioconductor.bsky.social
ABACBS/BioC Asia 2025 Workshops are coming! @ Adelaide 27-28 November. Join us in November for two days of deep-dive sessions on scalable bioinformatics, spatial omics, AI-driven genomics, and more blackochrelabs.au/abacbs2025_w... #Bioinformatics @abacbs.bsky.social @bioconductor.bsky.social
Stefano Mangiola reposted
π Curious about #SpatialOmics? Want to master spatial omics data analysis using #Rstats and @bioconductor.bsky.social ? π₯ Registrations are now OPEN for the 3rd edition of our hands-on course with @stemang.bsky.social ! π Save the dates: 18β20 May 2026 www.physalia-courses.org/courses-work...
Join us for another tidyomics meeting tomorrow! We will chat about several news - tidyprint - tidybulk V2 - omicslog - and more!
Our first Fall #tidyomics meeting will be this Wed 10 September, early in US / noon in Europe / late in Australia. Feel free to join if you're interested in what we are doing to make omics data more amenable to tidy data analysis. Organized with Stefano @stemang.bsky.social
Join us for an interesting discussion on using AI with foundational models in biology!
Next in our #AI webinars: Stefano Mangiola @saigenci.bsky.social talks AI models in #SingleCell and if they can uncover biological patterns Anh TN Nguyen @monashuniversity.bsky.social shares how deep learning is accelerating #DrugDiscovery for GPCRs More info www.biocommons.org.au/events/ai-se...
Join #AI and #Immunology! π’ Fully funded #PhD @saigenci.bsky.social: develop AI to chart immune diversity across the population, in #cancer. CV, transcript, and a one-page statement by 30 August 2025 β www.linkedin.com/feed/update/... #PhDOpportunity #MachineLearning #SingleCell
Two days to apply for a BiocAsia workshop! - Did you develop a package you want to showcase? - You want to share an analysis workflow for your favourite data type? This is your time to share this with the community! Submission -> biocasia2025.bioconductor.org @bioconductor.bsky.social
BiocAsia will collaborate with ABACBS for the 2025 conference (Adelaide) to bring you a full day of workshops! Have you thought about teaching a workshop about your or someone else's package or a workflow? This is the time! Submit your proposal by the 1st of August.
π£ BioCAsia 2025: Call for Workshops Join the Bioconductor stream at ABACBS 2025 in Adelaide! Submit your hands-on workshop EOI by August 1. Flexible 90-min blocks. β‘οΈ www.abacbs.org/abacbs-2025-... #Bioconductor #BioCAsia2025 #RStats
Stefano Mangiola reposted
Big thanks to everyone who made #GBCC2025 a fantastic week of science, collaboration, and community! Highlights for Bioconductor included keynotes, hands-on projects, and great conversations π»π§¬ @galaxyproject.bsky.social @bioconductor.bsky.social
What a cover! Looking forward to sharing our work with you!
Seminar this Friday July 4th 1.00pm: βModelling and Democratising the Human Cell Atlasβ with @stemang.bsky.social, Haroon Shakeel & Chen Zhan (@saigenci.bsky.social) Details & zoom info: doppeldata.au/events/event... #Bioinformatics #SingleCell #HumanCellAtlas #Adelaide #Genomics
Today, I had a blast at the @mig-unimelb.bsky.social MIG symposium, showcasing our use of mixed linear models at scale and #AI tools to study #singlecell cancer immunology. Thanks Heejung, Kim-Anh and all the MIG! events.unimelb.edu.au/MIG/event/45...
Thanks @physaliacourses.bsky.social, it was a blast! And the great active audience made it so enjoyable!
π Weβre wrapping up our 3-day Spatial Omics in R/ @bioconductor.bsky.social workshop! A huge THANK YOU to @stemang.bsky.social Malvika and all our attendees who made this event a success π Until next time β www.physalia-courses.org/courses-work... π§¬πΊοΈ #SpatialOmics #Bioconductor #RStat
Amazing crew! Tomorrow, we will show the Physalia crew how to use #tidyomics to manipulate and analyse spatial data!
π Just kicked off our Spatial Omics in R/Bioconductor course with @stemang.bsky.social In this 3-day course, we're gonna explore spatial technologies & hands-on data analysis in R and Bioconductor using tidy principlesπ§¬π§ π www.physalia-courses.org/courses-work... #SpatialOmics #RStats #Bioconductor
In few hours we have the second #tidyomics meeting! where we will talk about workshops, communication and education and more. Thursday March 27 with a Europe friendly meeting time (12:00 CET) Join the @bioconductor.bsky.social slack channel to know more #tidiness_in_bioc channel Join us
Great first #tidyomics meeting, covering 3 continents! π We discussed data representation with #tidyprint. Stay tuned for the next one to discuss workshop delivery, education and more! Join the slack channel #tidiness_in_bioc community-bioc.slack.com/archives/CEQ... @bioconductor.bsky.social
Great first #tidyomics meeting, covering 3 continents! π We discussed data representation with #tidyprint. Stay tuned for the next one to discuss workshop delivery, education and more! Join the slack channel #tidiness_in_bioc community-bioc.slack.com/archives/CEQ... @bioconductor.bsky.social
Tomorrow, we will have our first #tidyomics meeting for 2025! We will discuss how to centralise tidy display for biological data -> github.com/tidyomics/ti... Wednesday 12th of March - 4PM NY - 9PM London - 8AM (Thursday) Melbourne details -> community-bioc.slack.com/archives/CEQ... Pls share!
Stefano Mangiola reposted
π Interested Spatial Omics with R/Bioconductor? π§¨Do you want to learn how to analyse these data in R with the #tidyverse? Join us in May for this course with @stemang.bsky.social & @lgmartelotto.bsky.social π www.physalia-courses.org/courses-work... #SpatialOmics #Bioinformatics #RStats
Tomorrow, we will have our first #tidyomics meeting for 2025! We will discuss how to centralise tidy display for biological data -> github.com/tidyomics/ti... Wednesday 12th of March - 4PM NY - 9PM London - 8AM (Thursday) Melbourne details -> community-bioc.slack.com/archives/CEQ... Pls share!
Stefano Mangiola reposted
π Tidyomics next meeting is Wed, Mar 12 at 4PM NY / 9PM London / 8AM (Thurs) Melbourne. They'll discuss enhancing SummarizedExperiment display & seek feedback on tidyprint package. See Bioconductor Slack #tidiness-in-bioc channel or events calendar for more info: buff.ly/rdhL3jL #Tidyomics #RStats
π’ An exciting #Postdoc position opened in our laboratory for a junior #Bioinformatician! Developing #Bioinformatic and #AI tools to advance precision oncology using the available #singlecell / #spatial data universe. careers.adelaide.edu.au/cw/en/job/51... Pls share! π #postdocposition
We (Chen Zhan!) just launched #sccomp for #Python! Testing for differences in cell-type proportion in #singlecell #spatial data? #sccomp is a mixed-effect Bayesian model - Use sum-constrained BetaBinomial distribution - Outliers detect. - Remove unwanted effects github.com/MangiolaLabo...
Would you open your paper to a modular open-collaboration model? It was game-changing for #tidyomics If you love #crowdResearch and #CommunityBuilding have your say on the #crowdToPaper model guidelines Comment on the shared doc: docs.google.com/document/d/1... Please share π
π’π Dear Research Community! A call π to contribute to defining the #guidelines of the #CrowdToPaper research model, as tested for tidyomics doi.org/10.1038/s415... We welcome feedback from all research fields through comments on docs.google.com/document/d/1... π Plz Share! β€οΈThank you!
Stefano Mangiola reposted
π Ready to learn about Spatial Omics? Learn from @stemang.bsky.social & @lgmartelotto.bsky.social in this hands-on R/Bioconductor course! Master imaging vs. sequencing methods, experimental design & tidy data principles for cutting-edge spatial omics analysis www.physalia-courses.org/courses-work...
π’π»π§ͺ 2 #PhD #Scholarships available @SAiGENCI: 1) Hybrid wet-dry: #multiomics to predict neoadjuvant response in #cancer 2) #Bioinformatics, comp-bio: large-scale #singlecell modelling and infrastructure πhttps://researchers.adelaide.edu.au/profile/stefano.mangiola#my-research Please share! π