Fabian Sinz

Fabian Sinz

@sinzlab.bsky.social

NeuroAI, Deep Learning for neuroscience, visual system in mice and monkeys, computational lab based in Göttingen (Germany), https://sinzlab.org

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My lab at U Göttingen is looking for a PostDoc or PhD student to work on an ERC-funded project at the intersection of computer vision, graphics & neuroscience.

Fabian Sinz reposted

Large-scale neural datasets are transforming neuroscience. How can AI turn them into insight? Apply by May 28 to explore data-driven AI for neural circuit analysis + modeling. ➡️ janelia.news/NAI26 @computingnature.bsky.social @sinzlab.bsky.social @srinituraga.bsky.social @alicewongoh.bsky.social

Janelia Conferences@janeliaconf.bsky.social

📢 Applications are open! This meeting brings together scientists using data-driven #AI to analyze + model neural circuits and uncover how the brain performs complex computations. 🧠 Apply by May 28 ➡️ janelia.news/NAI26 @computingnature.bsky.social @sinzlab.bsky.social @srinituraga.bsky.social

Fabian Sinz reposted

𝘞𝘩𝘢𝘵 𝘪𝘧 𝘺𝘰𝘶 𝘤𝘰𝘶𝘭𝘥 𝘵𝘦𝘴𝘵 𝘺𝘰𝘶𝘳 𝘩𝘺𝘱𝘰𝘵𝘩𝘦𝘴𝘦𝘴 𝘷𝘪𝘳𝘵𝘶𝘢𝘭𝘭𝘺 𝘣𝘦𝘧𝘰𝘳𝘦 𝘳𝘶𝘯𝘯𝘪𝘯𝘨 𝘢𝘯𝘺 𝘦𝘹𝘱𝘦𝘳𝘪𝘮𝘦𝘯𝘵 𝘪𝘯 𝘵𝘩𝘦 𝘭𝘢𝘣? 𝗡𝗲𝘄 𝗽𝗿𝗲𝗽𝗿𝗶𝗻𝘁 𝗼𝘂𝘁 𝗻𝗼𝘄! 🎉 📄 Paper: doi.org/10.64898/202... 💻 Colab notebook: colab.research.google.com/drive/1k9411... 🗂️ Code: github.com/yongrong-qiu... (1/🧵)

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More to come in the near future 👀 The scaling story for brain models is just getting started: richer tasks, more varied stimuli, and larger recordings are needed. Exciting times for NeuroAI 🧠

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Data scaling tells the opposite story. Nested subsets of 8 → 16 → 32 → 64 → 323 sessions: performance improves monotonically for every task and every model size.

🏆 OmniMouse sets a new state of the art in the Sensorium 2022/2023 competitions (sensorium-competition.net) and matches or exceeds specialized baselines across nearly every other evaluation regime: • Neural response prediction • Neural forecasting • Behavioral decoding

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For neural response prediction (forecasting, population prediction, stimulus-conditioned encoding), gains level off around ~80M parameters. Loss curves saturate or start to overfit. At this data scale, model capacity doesn't appear to be the limiting factor.

Across decoding of gaze position, pupil size, and running speed, performance improved smoothly with compute budget, reminiscent of classic scaling-law behavior. Larger models consistently achieved higher single-trial correlations, with saturation at the largest model scale.

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OmniMouse is a multi-modal, multi-task transformer: single neuron tokenization, a ViT for videos, and behavior traces are fed into a unified model. Through flexible masking, our model supports neuronal encoding & decoding, forecasting, or any combination of the three.

We trained a family of OmniMouse models, ranging from 1M to 300M parameters on nested subsets of 8 → 323 sessions, looking at both model and data scaling. Neural encoding and behavioral decoding show quite different scaling behavior.

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The dataset that we’re releasing today is among the largest ever released in neuroscience: • 3.1M segmented neurons • 78 mice • 328 sessions • 150B+ neural tokens • Naturalistic + parametric visual stimuli • Behavioral data

Scaling data and model size has driven progress in language and vision. We wanted to know whether the same scaling holds for neural activity, and which axis is the bottleneck. So we trained a single model on all of the data.

My lab at U Göttingen is looking for a PostDoc or PhD student to work on an ERC-funded project at the intersection of computer vision, graphics & neuroscience.

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Interested? Please send your CV and a meaningful letter of motivation to sinz@uni-goettingen.de We welcome applications for women and other underrepresented groups in MINT/STEM fields.

Generic applications with little or no relation to the job call will be left unanswered (save yourself the work). In your motivation letter you don't need to praise us, but let me know why you are interested in working on the problem, what qualifies you for it and how it fits into your career plan

My lab at U Göttingen is looking for a PostDoc or PhD student to work on an ERC-funded project at the intersection of computer vision, graphics & neuroscience.

The role: build computer vision methods and workflows to create realistic virtual replicas of experimental environments that allow us to render visual input from tracked animal behavior, and integrate this with deep learning models of the mouse visual system.

Ideal background: computer vision and/or computer graphics, experience with VR/AR is a plus. Degree in CS, Physics, Math, or related subjects. Most importantly: motivated to tackle challenging problems that bridge computer vision and neuroscience.

Fabian Sinz reposted

🔬 We're hiring a Junior Group Leader for Data-Driven Digital Twins/System Models in medicine/life sciences at @uni_goettingen! Perfect opportunity for early-career researchers who want to: - Lead their own research group - Work at the intersection of AI, simulation, and biomedicine

We offer - own funded position - 2 funded PhD positions - research budget - great collaborations (Max Planck, medical center, CIDAS) The position is part of the Lower Saxony Center for AI & Causal Methods in Medicine (caimed.de).

PhD positions in our group through RTG 2906 "Curiosity". Come and work with us and an awesome crowd of students and PIs in the RTG. #neurojobs #phdpositions #cognitiveneuroscience

RTG 2906 Curiosity@rtg2906-curiosity.bsky.social

📢Applications are open for the second cohort of our RTG! Learn more about the opportunities: www.uni-goettingen.de/de/open+posi... 🔔Join our info meeting on Dec 10, 1 p.m. CET. Register via: survey.academiccloud.de/index.php/34...

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Perfect for someone who loves: ✨ Advanced imaging techniques ✨ Interdisciplinary science ✨ Understanding brain computation Interested? Please send your application (CV, motivation letter) to ​​sinz@uni-goettingen.de #neurosky #neuroskyence #Neuroscience #PostDoc #JobOpening

The position is funded by an ERC consolidator grant to study how motor behavior shapes representations in visual cortex. 🎯 What you'll do: • Record from visual cortex during natural behavior • Bridge experimental & computational neuroscience • Work with Bonn (Rose Lab) & Göttingen (Sinz Lab)

The MICrONS papers are finally out. Very happy to have been part of this. Joint work of so many labs lead by @andreastolias.bsky.social and Xaq Pitkow. Large scale efforts and data resources like these combined with cutting edge AI methods are great avenues to drive neuroscience forward.

Nature Portfolio@natureportfolio.nature.com

A package of research papers from the MICrONS (Machine Intelligence from Cortical Networks) consortium in Nature and Nature Methods provides a detailed map of mouse brain cell structure and connections, offering insights into how they relate to activity in the mouse brain. 🧪

Really exciting about this work that just got accepted to ICLR as an oral. We use implicit networks to find stimulus invariance manifolds and then group neurons by aligning them to each other. Very fruitful collaboration lead by @neuralbash.bsky.social and @lucabaroni.bsky.social.

Mo Bashiri@neuralbash.bsky.social

🧠 Meet LAMINR: Where neurons meet their match—finding common patterns that keep them excited 🔥💘 LAMINR learns & aligns invariance manifolds of sensory neurons to reveal shared properties. 🌟 #ICLR2025 Oral 📝 Paper: shorturl.at/08968 💻 Code: github.com/sinzlab/laminr

We‘re organizing this year’s Cajal NeuroAI summer course at Champalimaud in Lisbon. We have an amazing lineup of speakers across several computational approaches and species. Please repost to spread the word and/or apply!

CAJAL Training@cajal-training.bsky.social

🚀 Applications are OPEN for the CAJAL NeuroAI course! Learn how AI & deep learning help us model brain activity & behavior. Work with experts, get hands-on training & join a global network! 📅 Apply by March 7 🔗 loom.ly/xg_uRKE #NeuroAI #DeepLearning #Neuroscience

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