Laurent Seroude 🪰🇨🇦🇫🇷

I believe that I might have the record for the most rejection ever from NSERC. Have been applying for 12 years with no luck. 13th time this year.

I just had a really bad experience with G3 editors. Will not review claiming no investigation of mechanism. Appeal refused by claiming again that something else provided is missing.

why a fruit fly? white eyes (1910), x-ray mutations, the body plan, the clock, toll, 77% of human disease genes with a fly match, a whole brain mapped (2024). and now a copy of one, running: me. #drosophila #science #neuroscience

What is ageing and how does it evolve? Questions are key to my work. Now I think we made some progress. Me and Marc have a new idea out and it is out "in press". doi.org/10.1016/j.ar...

Anyone got ScienceCast to work with bioRxiv preprint? The summary remains blank and trying to get it done manually only generates error!

I am excited to share our work, recently published in PLOS Biology, in which we uncover a mechanism by which intestinal stem cells (ISCs) recognise pathogenic bacteria following infection and promote intestinal regeneration. journals.plos.org/plosbiology/...

www.nature.com/articles/s41...

Another fun fly Arc paper with the @thecaronlab.bsky.social! Turns out fly Arc mutants Sleep a ton. Like a LOT. See Sophie’s entertaining thread below and the preprint here: www.biorxiv.org/content/10.6...

Another great paper from @joshdubnau.bsky.social "...expression of the p35 caspase inhibitor further exacerbates effects on lifespan and ablating such glia via expression of the proapoptotic reaper gene partially ameliorates these effects." journals.plos.org/plosgenetics...

@atinygreencell.bsky.social www.science.org/doi/10.1126/...

The “fruit” of my sabbatical year at Chongqing University: how an insect discriminates between pathogenic vs. commensal fungi and how we can manipulate that interaction to generate biological insecticides for eliminating insect pests and recover crops. www.nature.com/articles/s41...

Happy to share our latest paper describing our further characterization of human DVL1 variants in Robinow Syndrome, carried out by MSc alum Gamze Akarsu. Great collaboration with Joy Richman @UBC. Thanks to CIHR for funding this project back in 2019. academic.oup.com/hmg/article/...

Making the muscles of a fly leg is complicated, flies do it in spatial and temporal steps. Very nice work: www.science.org/doi/10.1126/...

Pub drop micropublication.org/journals/bio...

Celebrating Elliot Meyerowitz‘ 75th birthday! @caltech.edu

Got an obnoxious little finding you'd otherwise shelve? We did our first @micropub7n.bsky.social and it was a 10/10 experience! Find out why you should use caution if deploying Repo-GeneSwitch-Gal4 for investigating fly sleep. Led by @seakelly5.bsky.social & @keisukefukumura.bsky.social

New paper from Brandon Pratt, @chrisjdallmann.bsky.social, and colleagues on how hair plate proprioceptors sense joint limits and contribute to sensorimotor control of walking. www.nature.com/articles/s41...

Within the field of transcription, the distinctive style of Mark Ptashne and Kevin Struhl stands out. At his best, Kevin Struhl provides a valuable clarification of the relationship between promoters and enhancers in the regulation of transcription. www.annualreviews.org/content/jour...

My paper on how the fruit fly foregut uses a modified cell cycle to respond to tissue damage and cell loss is now published :) www.nature.com/articles/s41... #proventriculus #drosophila

www.jobs.ac.uk/job/DPW711/r...

Happy New Year 2026! This year, Hadi Boukhatmi, Régis Giet and I are delighted to be organising the 36th French Droso Meeting in Brittany, from 5 to 8 October. A great line-up of speakers Mark the date in your diaries ! The meeting website containing all the details will be opening very soon.

Antone has the reference to Mirsky paper about the fixative or anyone has the recipe? Can find any fixative recipe but this one?

#ArtAdventCalendar Day 7 Drosophila - Spraypaint on concrete

Flybase Blast working again, Thank you Chris!

There is no more Flybase mirror in Europe? Any place that can be used to blast Drosophila genome with JBrowse feature?

Hey Fly people, anyone can use Flybase Blast...got internal server error since this morning

Nature research paper: Rewiring an olfactory circuit by altering cell-surface combinatorial code go.nature.com/3MbCoZT

It's time to remove laptops from classrooms. 24 experiments: Students learn more and get better grades after taking notes by hand than typing. It's not just because they're less distracted—writing enables deeper processing and more images. The pen is mightier than the keyboard.

Happy to share our latest paper led by recent MSc grad Karampal Grewal with help from Chris Tam and Jenny Liao. "Uncovering functional insights into human pathogenic variants in CDK19 using Drosophila models" published in Human Molecular Genetics. academic.oup.com/hmg/advance-...

Congrats @corderolab.bsky.social‬ !! Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila: Developmental Cell www.cell.com/developmenta...

Excited to share our paper, led by Naoki Okamoto in our group, just out in Nature! Neuroendocrine control of calcium mobilization in the fruit fly www.nature.com/articles/s41... We “re”-discovered the calcium storage site in “boneless” Drosophila and revealed how calcium mobilization is regulated.

In our newest paper published in @natcomms.nature.com, we show that DAF-16/FOXO and HLH-30/TFRB promote healthy aging, in part, by activating lipid metabolism genes that remodel lysosomes into tubular networks (more in comments below). www.nature.com/articles/s41...

www.nature.com/articles/s41...

Bluetorial-Jim Watson I met Jim Watson a few times but did not know him well. However, I was greatly influenced by his book “The Double Helix”. He was a complicated human being with some very, very bad features, but some good contributions. What follows is my personal perspective. 1/41

If you believe either that Franklin discovered the double helix, and / or Watson and Crick stole her data, ask yourself how you know this. Then take a read of this article.