SciLifeLab

SciLifeLab

@scilifelab.se

🇸🇪 Sweden's national center for molecular biosciences 👩‍🔬 Infrastructure with unique technologies and expertise 👥 Research community 🥼 Life science 🌱 💻 Often data-driven https://www.scilifelab.se/ https://www.linkedin.com/company/scilifelab/

2.6K followers273 following204 posts

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SciLifeLab
@scilifelab.se

Hey Bluesky! Given that we are new here, we thought an introduction might be in place. So, what is SciLifeLab? In short, we are a nonprofit research infrastructure based in Sweden, enabling life science research that would otherwise not be possible. 🧪🌍🖥️🧬

SciLifeLab
@scilifelab.se

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Arian Lundberg, PhD@arianlundberg.bsky.social

I'm #hiring at #KTH, #Sweden’s largest technical university, and @scilifelab.se in #Stockholm. We’re looking for a #postdoc in computational cancer biology, #multi-omics & #machinelearning to advance #cancer #precisionmedicine. kth.varbi.com/en/what:job/... #CancerResearch #Postdoc #MultiOmics

kth.varbi.comPostdoc in multi-omics machine learning and computational cancer biologyJob Description The lab is part of the SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS) and is based at SciLifeLab Stockholm and KTH. We develop and apply computational a

SciLifeLab reposted

Guillaume Gaullier
@guillawme.eurosky.social

Very happy to see this paper published! Got an excellent batch of monomeric photosystem I prepared by 1st author Jelena Boyka: the microscopy and image processing were a breeze (also thanks to the excellent #cryoEM facilities at @uu.se and @scilifelab.se). doi.org/10.1007/s111...

doi.orgHigh-resolution structure of monomeric photosystem I from Thermosynechococcus vestitus - Photosynthesis ResearchPhotosystem I (PSI) exists in trimeric (tPSI) and monomeric (mPSI) forms within the thylakoid membrane of cyanobacteria. PSI functions as a light-driven electron pump, enabling the transfer of electro...
SciLifeLab
@scilifelab.se

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Lehtiö Lab@lehtiolab.bsky.social

🎉 Very happy to share that our work on triciribine (TCN) in acute lymphoblastic leukemia is now published in npj Precision Oncology! A story about what an old drug is really doing inside leukemia cells. 🧵👇 www.nature.com/articles/s41...

nature.comMulti-omics profiling identifies triciribine as a biomarker-guided antimetabolite therapy for acute lymphoblastic leukemia - npj Precision Oncologynpj Precision Oncology - Multi-omics profiling identifies triciribine as a biomarker-guided antimetabolite therapy for acute lymphoblastic leukemia
SciLifeLab
@scilifelab.se

We're excited to welcome the #LongRead sequencing community to Uppsala, Sweden! 🧪 An opportunity to learn & exchange ideas within #biodiversity, #ClinicalDiagnostics, #transcriptomics, #epigenomics and more! 🗓️ November 2-4 📍 @uu.se Main Building Program and registration: www.lrua.se/registration/

lrua.seLong-Read Sequencing Uppsala, November 2–4, 2026#LRUA26: Empower your research with long-read sequencing technologies and connect with experts, peers, and industry leaders in Uppsala this November.
SciLifeLab
@scilifelab.se

“As an electrophysiologist, I’m especially excited to see a @nobelprize.org that puts ion channels in the spotlight. The discovery of channelrhodopsin transformed a naturally occurring light-gated ion channel into a tool that revolutionized neuroscience,” says Nina Ottosson.

SciLifeLab
@scilifelab.se

The 2026 Nobel Prize in Physiology or Medicine is awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel, “for their discoveries concerning light-gated ion channels and optogenetics”.

SciLifeLab reposted

Jochen Schwenk
@jochwenk.bsky.social

Great collaborative paper just came off the press: Systematic identification of p11 as a signaling modulator across the GPCRome | #ScienceAdvances www.science.org/doi/10.1126/... @kthuniversity.bsky.social @scilifelab.se @ki.se @rockefeller.edu

science.orgSystematic identification of p11 as a signaling modulator across the GPCRomeThe microprotein p11 (S100A10) is a ubiquitously expressed molecular scaffold that is known to be required for behavioral responses to certain antidepressants, presumably through its effect on G prote...

SciLifeLab reposted

Claudio Cantù
@claudiocantu81.bsky.social

CUT&ID does Genomics+Proteomics in one shot via the fusion protein Lazarus Out @narjournal.bsky.social Unstoppable @annanordin.bsky.social is thinker+executor Get in touch if you wish to try it—plasmid soon @addgene.bsky.social 🙏 @liu.se @scilifelab.se @kawresearch.bsky.social @cancerfonden

Claudio Cantù@claudiocantu81.bsky.social

Can one map the genome-wide binding (1) and its protein partners (2) simultaneously from the same sample? Yes, one can. with CUT&ID ✂️🪪 Spearheaded — singlehandedly — by @annanordin.bsky.social No need of transgenesis, cloning and overexpression. Check it out, it's fast and its works.

SciLifeLab reposted

Karolinska Institutet
@ki.se

The protein p11 interacts with numerous receptors targeted by commonly used medicines, opening new possibilities for treating conditions like pain, inflammation and depression. Study from KI, @scilifelab.se & @rockefeller.edu published in Science Advances 🧪 #Pharmacology news.ki.se/protein-foun...

news.ki.seProtein found to regulate dozens of important drug targetsA small protein known as p11 may play a much broader role in cellular signaling than previously thought. Researchers at Karolinska institutet have now shown that p11 interacts with numerous receptors ...
SciLifeLab
@scilifelab.se

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Claudio Cantù@claudiocantu81.bsky.social

I will hire a Postdoc to study the genomic determinants of tumor heterogeneity Please, get in touch if interested, or help me spread the voice @scilifelab.se @kawresearch.bsky.social @liu.se liu.se/en/research/...

liu.seThe Cantù Lab - Genome Regulation in Development and DiseaseThe Cantù Lab at LiU is focused on one important goal: to discover the mechanisms of genome regulation that drive cell differentiation and specialization during embryonic development.
SciLifeLab
@scilifelab.se

Today, we were honored to welcome Nobel laureate Stefan Hell 🧪 “I hear Stefan speak about his research once a year, and I’m always amazed how much has happened,” says SciLifeLab Director Jan Ellenberg. Hell received the 2014 Nobel Prize in Chemistry.

SciLifeLab
@scilifelab.se

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Nature Biotechnology@natbiotech.nature.com

The SciLifeLab PULSE entrepreneurial model: accelerating drug discovery by bridging academia and industry - @scilifelab.se www.nature.com/articles/s41...

nature.comThe SciLifeLab PULSE entrepreneurial model: accelerating drug discovery by bridging academia and industry - Nature BiotechnologyA scalable blueprint for postdoctoral training embeds entrepreneurial venture mechanics and industry mobility directly into academic infrastructure to cultivate ‘T-shaped’ scientific leaders.
SciLifeLab
@scilifelab.se

A new study led by Erdinc Sezgin (@sciezgin.bsky.social) has developed a method for measuring the physical properties of cell membranes in thousands of individual immune cells simultaneously! 🧪 Read more in the article below ↓ www.scilifelab.se/news/a-new-w...

scilifelab.seA new way to read immune cells through their membranesA new study published in Nature Chemical Biology by researchers from SciLifeLab and Karolinska Institutet has developed a method for measuring the physical properties of cell membranes in thousands of...

SciLifeLab reposted

Palesa
@palaeoprotpalesa.bsky.social

This line “happy to skip writing for the next deadline”!!!! 🥹🥹🥹 Congrats to Florian and the team!

SciLifeLab@scilifelab.se

“I'm grateful, freaking out, humbled, very excited about what we’re going to do, happy to skip writing for the next deadline, and eager to celebrate with my wonderful team!” says Florian Rosenberger (SciLifeLab/@ki.se) after receiving an @erc.europa.eu Starting Grant 🧪 #proteomics #MassSpec

scilifelab.seA “smörgåsbord of feelings”: Florian Rosenberger celebrates €1.5M ERC Starting GrantFlorian Rosenberger receives a ERC Starting Grant, and adds his name to the growing list of SciLifeLab Fellows receiving prestigious grants.
SciLifeLab
@scilifelab.se

“I'm grateful, freaking out, humbled, very excited about what we’re going to do, happy to skip writing for the next deadline, and eager to celebrate with my wonderful team!” says Florian Rosenberger (SciLifeLab/@ki.se) after receiving an @erc.europa.eu Starting Grant 🧪 #proteomics #MassSpec

scilifelab.seA “smörgåsbord of feelings”: Florian Rosenberger celebrates €1.5M ERC Starting GrantFlorian Rosenberger receives a ERC Starting Grant, and adds his name to the growing list of SciLifeLab Fellows receiving prestigious grants.
SciLifeLab
@scilifelab.se

Advanced #3Dimaging and #SpatialTranscriptomics are brought together to better understand #PulmonaryHypertension – a life-threatening condition for which current treatments can slow disease progression and relieve symptoms, but not target the underlying cause. ↓ 🧪 www.scilifelab.se/news/combini...

scilifelab.seCombining 3D imaging and spatial biology to understand pulmonary hypertensionPulmonary hypertension is a life-threatening condition for which current treatments can slow disease progression and relieve symptoms, but not target the underlying cause. A demonstrator project…
SciLifeLab
@scilifelab.se

Are you working across biological scales, exploring how #ecosystems respond to global change, developing more #SustainableFood systems, or addressing #biodiversity loss? 🧪 Check out the great line-up of invited speakers and join us to share your work, exchange ideas and be part of the discussion!

SciLifeLab
@scilifelab.se

Our annual flagship event, the SciLifeLab Science Summit, this year unites world-leading #cancer researchers with cutting-edge technologies across #genomics, #proteomics, #imaging, #DataScience and beyond 🧪 🗓️ October 14, 2026 More info and registration ↓ www.scilifelab.se/event/scilif...

scilifelab.seSciLifeLab Science SummitThe Annual Conference SciLifeLab Science Summit is a one-day symposium with a new topic each year. The 2026 topic is: Cancer Research: Translating Life Science Discoveries to Clinical Breakthroughs Fo...

SciLifeLab reposted

Biodiversity Genomics Europe plus (BGE+)
@biogeneurope.bsky.social

Our colleagues @scilifelab.se organise 2 conferences in Oct/Nov, "Integrating Scales in Planetary hashtag#Biology" and the "Long-Read Users Annual 2026". Both in Uppsala (Sweden). Both consecutive. More info: biodiversitygenomics.eu/conferences-... @ergabiodiv.bsky.social @iboleurope.bsky.social

biodiversitygenomics.euUpcoming interesting conferences at SciLifeLab - BGE+SciLifeLab organises two consecutive conferences by the end of October and the beginning of November 2026. A great opportunity to spend a few formative days in Uppsala! Integrating Scales in Planetary...

SciLifeLab reposted

Erdinc Sezgin
@sciezgin.bsky.social

New paper alert 🎇 in @biologists.bsky.social Journal of Cell Science.. Cell surface remodeling caused by the loss of the flippase subunit TMEM30A in immune cells: journals.biologists.com/jcs/article/...

journals.biologists.comCell surface remodeling caused by the loss of the flippase subunit TMEM30A in immune cellsSummary: TMEM30A loss disrupts membrane lipid asymmetry, increasing phosphatidylserine exposure, membrane dynamics and surface remodeling, linking flippase dysfunction to immune cell interactions.
SciLifeLab
@scilifelab.se

To learn the latest techniques in #StructuralBiology, participants travel to Stockholm, Linköping, Lund, and Gothenburg across two weeks, in the Integrated Structural Biology course organized by SciLifeLab and NordStruct. 🧪 More ↓ www.scilifelab.se/news/demysti... #MolBiol #Imaging

scilifelab.se"It’s harder than it looks": demystifying structural biology across sweden“It feels like a pretty natural progression in my career, to start picking up these methods that complement what I do, to become an even better structural biologist. There’s a lot of talk about integr...
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SciLifeLab
@scilifelab.se

“You get some ideas about what people can do and how difficult it is ... It’s harder than it looks when you’re sitting at a conference and someone talks about what they’ve done,” says participant & research engineer Anton Sellerberg. 🧪

SciLifeLab
@scilifelab.se

To learn the latest techniques in #StructuralBiology, participants travel to Stockholm, Linköping, Lund, and Gothenburg across two weeks, in the Integrated Structural Biology course organized by SciLifeLab and NordStruct. 🧪 More ↓ www.scilifelab.se/news/demysti... #MolBiol #Imaging

scilifelab.se"It’s harder than it looks": demystifying structural biology across sweden“It feels like a pretty natural progression in my career, to start picking up these methods that complement what I do, to become an even better structural biologist. There’s a lot of talk about integr...
SciLifeLab
@scilifelab.se

"Structural biology is developing into more and more integration between techniques and therefore networking is crucial”, says Cecilia Persson, Platform Coordination Officer at the SciLifeLab Integrated Structural Biology Platform and organizer of the course. 🧪

SciLifeLab reposted

Erdinc Sezgin
@sciezgin.bsky.social

New paper alert 💥 "Spectral biophysical cytometry with nanosensors reveals remodelling of immune cells in atherosclerosis" Open access paper here: www.nature.com/articles/s41...

nature.comSpectral biophysical cytometry with nanosensors reveals remodelling of immune cells in atherosclerosis - Nature NanotechnologyMembrane-permeant, environment-sensitive nanosensors enable high-throughput, multiparametric quantification of membrane order and mitochondrial potential, revealing immune-cell-specific remodelling an...

SciLifeLab reposted

Claudio Cantù
@claudiocantu81.bsky.social

FASTEN YOUR SEATBELTS: Tamina Weiss, inspired by previous data from @ppagella86.bsky.social found that beta-catenin is more than an adaptor protein downstream of #WNT It is an orchestrator that scouts and opens enhancers for transcriptional activation @biorxivpreprint.bsky.social

bioRxivpreprint@biorxivpreprint.bsky.social

Enhancer pioneering activity of Wnt/β-catenin signaling https://www.biorxiv.org/content/10.64898/2026.06.12.731851v1

SciLifeLab reposted

Claudio Cantù
@claudiocantu81.bsky.social

Hepatoblastoma is a nasty childhood liver cancer driven by mutant β-catenin How tumor cells get different and more or less aggressive? We found this out w Peng & Thomas from the Princess Maxima Center for Pediatric Oncology & @annanordin.bsky.social @liu.se @pnas.org www.pnas.org/doi/10.1073/...

pnas.orgDifferential Wnt/β-catenin signaling via TCF7L2/LEF1 binding specificity shapes cellular and tumor phenotypes | PNASThe mechanisms by which Wnt/β-catenin signaling regulates gene expression in a tissue- and context-specific manner remain poorly understood, limiti...

SciLifeLab reposted

Rocío Mercado Oropeza
@rociomer.bsky.social

My collaborator @ospjuth.bsky.social is recruiting a postdoc in cell biology to work on CRISPR perturbation and high-content imaging as part of our TIMED NEST project. Amazing team, please share! For information on how to apply, see the ad below: www.uu.se/en/about-uu/... #chemsky #chemjobs

uu.sePostdoc in Cell Biology – CRISPR Perturbation and High-Content Imaging - Uppsala UniversityPostdoc in Cell Biology – CRISPR Perturbation and High-Content Imaging, Department of Pharmaceutical Biosciences, Uppsala University
SciLifeLab
@scilifelab.se

The Science Magazine & SciLifeLab Prize is awarded annually to four young scientists for outstanding #LifeScience research based on a doctoral degree – and the essay they write about it. 🧪 Do you know someone who could apply? Share this – and the link below – with them! ↓ scienceprize.scilifelab.se

scienceprize.scilifelab.seScience & SciLifeLab Prize for Young Scientists – celebrating excellent young researchersThe Science & SciLifeLab Prize for Young Scientists is a global prize, established in 2013, aimed at rewarding scientists at an early stage of their careers.

SciLifeLab reposted

Claudio Cantù
@claudiocantu81.bsky.social

FINAL CALL! Register by the end of May to this year's edition 23-26 June 2026 Focus will OMICS data integration, with hands-on computation🧬 💻 Check out the program and your stellar teachers: www.trippus.net/summerschool... @scilifelab.se @kawresearch.bsky.social @remeseiro-lab.bsky.social

trippus.netSummer School 2026Come to this beautiful Swedish inland scenario to learn the most advanced technologies to study transcriptional regulation.
Claudio Cantù@claudiocantu81.bsky.social

The PALS Summer School in Transcriptomics, I promise, will be a unique experience www.trippus.net/summerschool... 23-26 June 2026 in a hidden Swedish paradise 🇸🇪🫎 We have extended the deadline to May 15 or until availability @scilifelab.se @kawresearch.bsky.social @remeseiro-lab.bsky.social

event.trippus.netSummer School 2026Come to this beautiful Swedish inland scenario to learn the most advanced technologies to study transcriptional regulation.
SciLifeLab
@scilifelab.se

'Acting locally for global impact' is this year’s theme for International Day for #BiologicalDiversity 🧪🌍 So, we thought we would highlight efforts and research you might have missed – from short articles to longer videos ↓ www.linkedin.com/pulse/scilif... #BiodiversityDay #IDB2026 #biodiversity

linkedin.comThe SciLifeLab Snapshot #2 - Exploring biological diversity“Acting locally for global impact” is the theme for this year’s International Day for Biological Diversity. “Major changes begin on a small, local scale.
SciLifeLab
@scilifelab.se

How did the Atlantic herring adapt to brackish water? 🧪🌍🐟 A Leif Andersson (SciLifeLab/@uu.se) led study finds that mutations in four specific genes were particularly important. Learn more in the UU press release ↓ www.uu.se/en/press/pre...