SBGrid Consortium

Community Announcements: Upcoming events from our partners at @instruct-eric.bsky.social Instruct course on Virtual Drug Screening (VDS) Nov 10-11, 2026 | Madrid, Spain Organized in collaboration with @cnb-csic.bsky.social. Register here: buff.ly/l4SRFDC #SBGrid #Collab

SBGrid's eLife paper received a citation in September from @heppnerd.bsky.social at @ubuffalo.bsky.social in @angewandtechemie.bsky.social International Edition. Read more here: buff.ly/vLP9TXj #SBGrid #StayConnected

New Member Alert: In September, Craig Lindsley from @vanderbilt.edu joined SBGrid. Welcome!!

SBGrid's eLife paper received a citation in September from Peter Dahlberg at SLAC National Accelerator Laboratory in ACS Nano: Cryo-Electron Tomography Reveals Nanoscale Thick Filament Disorganization in MYH7 P710R Hypertrophic Cardiomyopathy Cardiomyocytes. Read more here: buff.ly/CxMh1qu #SBGrid

SBGrid's eLife paper received a citation in September from Gira Bhabha at @jhu.edu in Journal of Biological Chemistry. Read more here: buff.ly/VMOD1le #SBGrid #Stayconnected

Community Announcements: Upcoming events from our partners at @instruct-eric.bsky.social. Scipion for Facilities Workshop Oct 29-30, 2026| Madrid, Spain Organized in collaboration with @cnb-csic.bsky.social (CNB) Register here: buff.ly/Xr6cgsb #SBGrid #Collab

SBGrid's eLife paper received a citation in September from @gogo-science.bsky.social at Icahn School of Medicine at Mount Sinai in @jvico-eics.bsky.social. Read more here: buff.ly/EMOFv5v

New Title Alert: PottsMPNN- is a protein design model for generating sequences from protein structures and predicting the energetic effects of mutations. More here: buff.ly/cxeDtfO #SBGrid #Software #StructuralBiology

New Title Alert: Mosaic- is a graphical tool for analysing and modelling biological membranes from 3D structural data. It combines tomogram import, membrane segmentation and surface meshing with protein localization and geometric measurements. More here: buff.ly/3eHUdPD #SBGrid #StructuralBiology

Community Announcements: Upcoming events from our partners at @instruct-eric.bsky.social. Structural Biology Meeting at Instruct-IT October 20, 2026 | Florence, Italy Details here: buff.ly/syqqHD2 #SBGrid #Collab

New Member Alert: Sarah Doore from University of Florida joined SBGrid in September. Welcome!!

On October 13th at 12pm ET, Prof Beata Turoňová from @mpibp.bsky.social will kick off our 2026-2027 software webinar series with an introduction to cryoCAT, a library of contextual analysis tools for cryo electron tomography & subtomogram averaging. More here: buff.ly/R6ZdW1B #SBGrid #Webinars

Monkeypox has no treatment. Scientists just found its weak spot: Vina Nguyen highlights the lab of Jonathan Abraham of @harvardmed.bsky.social & colleagues that appeared in @nature.com. Read more here: buff.ly/MkegGEq #SBGrid #CryoEM #MonkeyPox

Technical Notes: This month's software push includes updates to 11 titles -- Amber, BindCraft, ChemEx, HTSlib, IMOD, NAMD, Octopi, Picard, PolNet, PowerFit, and Warp. More here: buff.ly/7vPHwES #SBGrid #Software #StructuralBiology

Bacterial Xenophilia: mechanisms behind foreign DNA import: Cariuna Ellison's highlight features a publication in @narjournal.bsky.social from Manuela Hospenthal & fellow researchers at @ethz.ch. Read more here: buff.ly/QqvGbG0 #SBGrid #DNA #Bacteria

Request personal credentials to install & maintain a subset of software on laptops or home workstations. It's free for all users in SBGrid member groups & ensures that you have access to the same software tools whether at home or in the lab. Request credentials here: buff.ly/inuva2Q #StayConnected

Our September Tale features Shawn Zheng. At @biohub.org, Zheng's algorithm devevelopment team continues to develop AreTomoLive for reconstructing tomograms & data denoising, while casting an eye toward particle picking. Read more here: buff.ly/Ogt15Ms #Stayconnected #SBGridTales

SBGrid's eLife paper received a citation in August from Guy Schoehn from IBS Grenoble – Research group in Journal of Molecular Biology: High-resolution Structure of the Vaccinia Virus Phospholipase D-fold Endonuclease K4. Read more here: buff.ly/lADXxht #SBGrid #StayConnected

Upcoming events from our partners at @instruct-eric.bsky.social Instruct SI CryoEM Workshop 2026, Single Particle Analysis November 10-12, 2026 | National Institute of Chemistry, Ljubljana, Slovenia Application deadline: October 2, 2026 Register here: buff.ly/A834j32 #SBGrid #Collab

SBGrid's eLife paper received a citation in August from Bo Liang from Emory University School of Medicine in Microorganisms MDPI: Unreacted RSV Polymerase Structures Expand the Post-Translocation Landscape of the Nucleotide Addition Cycle. Read more here: buff.ly/FIoDOHt #SBGrid #ScienceMatters

New Member Alert: @scottboydlab.bsky.social from @stanforduniversity.bsky.social joined SBGrid in August. Welcome!!

New Member Alert: @angelasteinauer.bsky.social from École Polytechnique Fédérale de Lausanne joined SBGrid in August. Welcome!!

Technical Notes: XDS licensing change XDS is now licensed through DECTRIS & will remain freely available for nonprofit users w/ the added bonus that time-bound version limitations no longer apply. The first release from DECTRIS is out (see software changes below for details). #SBGrid #Updates

SBGrid's eLife paper received a citation in August from Andrew Kruse from @harvardmed.bsky.social in @pnas.org : Activation of the angiotensin II type I receptor by a nonpeptide agonist. Read more here: buff.ly/BQo4Arj #SBGrid #StayConnected

Technical Notes: macOS 27 expected this fall Apple is expected to release macOS 27 in the fall, & as w/ many new operating system releases, we recommend that users delay updating until the bugs are worked out. Contact us at bugs@sbgrid.org to report any problems you encounter. #SBGrid #Updates

New Member Alert: Stephen Ragsdale from @umich.edu Medical School joined SBGrid in August. Welcome!!

SBGrid's eLife paper received a citation in August from Eric Fischer from @danafarber.bsky.social in @nature.com DCAF11-dependent molecular glue degrader activated by glutathionylation. Read more here: buff.ly/q63j29D #SBGrid #ScienceMatters

SBGrid's eLife paper received a citation in August from Peter Dahlberg at Stanford University in @pubs.acs.org Nano: Cryo-Electron Tomography Reveals Nanoscale Thick Filament Disorganization in MYH7 P710R Hypertrophic Cardiomyopathy Cardiomyocytes. Read more here: buff.ly/XPuZ85a #SBGrid

Community Announcement: Upcoming events from our partners at @instruct-eric.bsky.social Instruct-ERIC Industry Webinar - Mass Photometry to support Structural Biology Research October 13, 2026 | Virtual Presented in collaboration with Refeyn Register here: buff.ly/HP2YvTE #SBGrid #Collab

Fisk University student Cariuna Ellison's highlight features a @pnas.org paper from Kate Ferguson's lab at @yale.edu School of Medicine. Ferguson's group identifies the activation mechanisms of an important protein receptor, EGFR, linked to cancer. Read more here: buff.ly/iCcj7Wu #SBGrid #Protein

New Title Alert: OCTOPI- is a deep-learning framework for automated 3D particle picking in cryo-electron tomography, with tools for training and running 3D U-Net models and automatically exploring model configurations. More here: buff.ly/WXgAVEN #SBGrid #Software

Antibodies guiding cancer immunotherapy: a publication in @cp-cancercell.bsky.social w/ contributions from Priyamvada Acharya & colleagues from @dukemedschool.bsky.social. Read more here: buff.ly/CrOio1I #SBGrid #Cancer #Antibody

Community Announcement: Upcoming events from our partners at @instruct-eric.bsky.social Instruct-ERIC Webinar Series: Structure Meets Function 49 September 15, 2026 | Virtual Register here: buff.ly/F3iUBMc #SBGrid #Collab

The not so easy job of protecting our DNA: a publication in @natsmb.nature.com from the lab of Nikola Pavletich at @mskcancercenter.bsky.social in which researchers describe the structure of ATR-ATRIP complex bound to its two activators. Read more here: buff.ly/S5IWOVw #SBGrid #DNARepair

August's software push includes - AlphaFold3, AlphaPulldown, AmberTools, CCP4, Chromap, COOT, cryoDRGN, DIALS, Foldtree, ICM Browser, NMRFx-Anaylst, OpenFold3, Open Force Field Toolkit, OpenMM, pyCoAn, pytom-match-pick, RDKit, Scipion, Schrödinger, Warp, and XDS. More here: buff.ly/wN9LYyJ #SBGrid

Community Announcement: Instruct.SI CryoEM Workshop 2026, Single Particle Analysis 11/10-11/12, 2026 | National Institute of Chemistry, Ljubljana, Slovenia Register here: buff.ly/cdTUjrU

New Event Alert: The SBGrid CryoEM Cloud Tournament! Teams worldwide will analyze the same confidential, unpublished CryoEM dataset in a preconfigured AWS cloud environment, competing to deliver the most accurate, efficient, & scientifically useful results. More here: buff.ly/LvTjHbb #SBGrid #AWS

New Member Alert: In August, @yoonseokkim.bsky.social from École Polytechnique Fédérale de Lausanne joined SBGrid. Welcome!!

Our software webinar series will resume in October with Beata Turoňová, Group Leader at the @mpibp.bsky.social, introducing cryoCAT. Until then, you can catch up on webinars you missed from our last series on the SBGrid YouTube channel. More here: buff.ly/p1w3J7S #SBGrid #Webinars

Our August Tale features Prof. Mihnea Bostina, who reflects on his scientific transit across the globe & finally making his home in New Zealand. From his laboratory at the @universityofotago.bsky.social. Read more here: buff.ly/Af3qVLc #SBGridTales #StayConnected

New Member Alert: Taha Shahid from the @unibirmingham.bsky.social joined SBGrid in July. Welcome!!

SBGrid's eLife paper received a citation in July from frank sicheri from @utoronto.ca in @natcomms.nature.com: Structure and mechanism of inhibition of lysine demethylase 2A (KDM2A) by compound 183c. Read more here: buff.ly/7caT1d5 #SBGrid #StayConnected

SBGrid's eLife paper received a citation in July from karin reinisch from of @yaleschoolofmed.bsky.social in @cp-molcell.bsky.social: Cryo-EM structure of soluble VPS13C suggests its regulation by a conformational switch and by calmodulin. Read more here: buff.ly/T0eFlS3 #SBGrid #ScienceMatters

New Title Alert: Hax- is a package that includes several tools to study conformational heterogeneity from CryoEM data. More here: buff.ly/u9NPogU #SBGrid #Software #StructuralBiology

SBGrid's eLife paper received a citation in July from Pedro Pereira from Universidade do Porto in Protein Science: A cryptic aromatic binding pocket in the highly thermostable GpgS from Mycobacterium hassiacum hints at MGLP pathway crosstalk. Read more here: buff.ly/oJ6bpFN #SBGrid #StayConnected

New Member Alert: In July, Lisa Olshansky from University of Illinois at Urbana-Champaign joined SBGrid. Welcome!!

SBGrid's eLife paper received a citation in July from @palencialab.bsky.social from @ugrenoblealpes.bsky.social in @jacs.acspublications.org. Read more here: buff.ly/HgcuBEZ #SBGrid #StayConnected

Community Announcement: Mass Photometry to support Structural Biology Research 10/13/26 | Virtual Join to learn about how to access Mass Photometry technologies through Instruct-ERIC and hear from scientists who have used Mass Photometry in their research. Register here: buff.ly/0c3VcSn

New Title Alert: DisVis- is a Python package and command line tool to visualize and quantify the accessible interaction space of distance restrained binary biomolecular complexes. More here: buff.ly/3AlzIzu hashtag#SBGrid hashtag#Software hashtag#StructuralBiology

New Member Alert: Arthur Neuberger from @lmu.de joined SBGrid in July. Welcome!!