Sage Science

🧬 The PippinHT was part of the library prep behind the most complete vanilla genome to date — the first V. planifolia assembly anchored to all 16 chromosome pairs, out in BMC Genomics. SMRTbell libraries were size-selected at a 6 kb high-pass cutoff before PacBio HiFi. Open access:

PippinHT was part of the workflow behind the first complete genome of a songbird 🐦 Our >10 kbp size selection prepped the PacBio HiFi library for this fully phased, T2T zebra finch reference from @erichjarvis.bsky.social and @vertebrategenomes.bsky.social - now out in @cellpress.bsky.social

The Sage Science MegaPulse™ is here! A pulsed-field electrophoresis power supply supporting FIGE and ZIFE on standard agarose midi gels. 7 pre-validated protocols with 0.5 kb–1.6 Mb resolution. Built for HMW DNA analysis and long-read sequencing library prep. sagescience.com/blog/new-meg...

New citation! MASTR-seq harnesses BluePippin size selection to revolutionize short tandem repeat analysis for rare disease diagnostics. Multiplexed, accurate, single-molecule resolution. Read more: sagescience.com/citation/mas... | Full paper: doi.org/10.1016/j.cr...

Thanks to the following sponsors who are supporting the 2026 JAX Long-Read Sequencing Workshop! @sagescience.bsky.social @twistbioscience.com @pacbio.bsky.social @nebiolabs.bsky.social @idtdna.bsky.social @rnaconnect.bsky.social @nabsys.bsky.social @iconpcr.bsky.social Illumina Sampled

Landmark study unravels the Oryza pangenome with an eye toward breeding more resilient rice strains for more sustainable agriculture. Led by Rod Wing at the Arizona Genomics Institute and #KAUST in collaboration with #Wageningen Univ. and others. Read our blog: sagescience.com/blog/uncateg...

Great review article from @cshlnews.bsky.social and @genomeresearch.bsky.social about the state-of-the-art of long-read targeted sequencing. From the “Long-Read Special Issue” genome.cshlp.org/content/34/1...