Raphael Meier MD PhD

Raphael Meier MD PhD

@raphaelmeier.bsky.social

Transplant surgeon

1K followers1.1K following20 posts

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Raphael Meier MD PhD
@raphaelmeier.bsky.social

Grateful to have worked on this with such an outstanding team.

PARCC@parcc-inserm.bsky.social

New Review: where xenotransplantation stands, and how multimodal precision diagnostics could help overcome the last immunological and clinical barriers to its clinical use. Read More: www.nature.com/articles/s41...

nature.comMultimodal precision diagnostics in clinical xenotransplantation - NatureNow that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional diagnostics often miss; a multimodal precision diagnost...
Raphael Meier MD PhD
@raphaelmeier.bsky.social

Grateful to have worked on this with such an outstanding team.

Climate, Ecology, War & More: Dr. Glen Barry BigEarthData.ai@bigearthdata.ai

Multimodal precision diagnostics in clinical xenotransplantation ->Nature | More on "Organ transplantation and donor shortage" at BigEarthData.ai

nature.comMultimodal precision diagnostics in clinical xenotransplantationGBD 2021 Diseases and Injuries Collaborators. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet 403, 2133–2161 https://doi.org/10.1016/S0140-6736(24)00757-8 (2024). GBD 2021 Forecasting Collaborators. Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021. Lancet 403, 2204–2256 https://doi.org/10.1016/S0140-6736(24)00685-8 (2024). Anderson, D. J. & Locke, J. E. Progress towards solving the donor organ shortage. Nat. Rev. Nephrol. 19, 83–84 https://doi.org/10.1038/s41581-022-00664-y (2023). Sykes, M. Developing pig-to-human organ transplants. Science 378, 135–136 https://doi.org/10.1126/science.abo7935 (2022). Yamada, K., Griesemer, A. & Okumi, M. Pigs as xenogeneic donors. Transplant. Rev. 19, 164–177 https://doi.org/10.1016/j.trre.2005.10.004 (2005). Sykes, M. & Sachs, D. H. Progress in xenotransplantation: overcoming immune barriers. Nat. Rev. Nephrol. 18, 745–761 https://doi.org/10.1038/s41581-022-00624-6 (2022). Parker, W., Bruno, D., Holzknecht, Z. E. & Platt, J. L. Characterization and affinity isolation of xenoreactive human natural antibodies. J. Immunol. 153, 3791–3803 https://doi.org/10.4049/jimmunol.153.8.3791 (1994). Galili, U., Shohet, S. B., Kobrin, E., Stults, C. L. & Macher, B. A. Man, apes, and Old World monkeys differ from other...
Raphael Meier MD PhD
@raphaelmeier.bsky.social

Privileged to collaborate with colleagues from various institutions on this update for the @amjtransplant.bsky.social —Best practices in islet #transplantation in mice—Our review explores preclinical models to treat #diabetes #rememberingDavidSutherland www.sciencedirect.com/science/arti...

sciencedirect.comBest practices in islet transplantation in miceIslet transplantation in mice serves as a crucial preclinical model for understanding alloimmune and autoimmune mechanisms, optimizing immunosuppressi…
Raphael Meier MD PhD
@raphaelmeier.bsky.social

Merci LeTemps pour ce bel article 🔹2e xénogreffe réussie à @mgh_transplant 🔹FDA approuve les essais cliniques 🔹NYU: une patiente >2,5 mois post-xenogreffe–un record 🔹UMB: recherche en Xénoperfusion de foie porcin pour l’insuffisance hépatique aiguë bit.ly/4gC4V4C

bit.lyLes essais de xénotransplantation de reins de cochons s’accélèrent et livrent un premier espoir - Le TempsAux Etats-Unis, les tentatives de greffe d’organes animaux sur des patients se succèdent depuis un an. Pour la première fois, une patiente américaine a survécu plus de deux mois. Un essai clinique a é...
Raphael Meier MD PhD
@raphaelmeier.bsky.social

Fascinating story of a 25yo patient with Type 1 diabetes, two previous liver transplants & a failed pancreas transplant receiving chemically-induced pluripotent stem cell-derived islets from adipose-derived MSCs. #stemcelltherapy #diabetes #transplant #medicine www.sciencedirect.com/science/arti...

sciencedirect.comTransplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patientWe report the 1-year results from one patient as the preliminary analysis of a first-in-human phase I clinical trial (ChiCTR2300072200) assessing the …
Raphael Meier MD PhD
@raphaelmeier.bsky.social

Captured this photo of the Milky Way — a powerful reminder of the vast complexity of our world. Much like in transplantation, every detail matters, yet the whole picture still holds mysteries that humble us #astrophotography #NightSky #Science #Transplant

Raphael Meier MD PhD reposted

Bluesky
@bsky.app

📢 App Version 1.60 is rolling out now (1/5) We have a new logo! 🦋  Bluesky is emerging from its cocoon of clouds to transform into a social butterfly. Read more about why we chose this logo here: blueskyweb.xyz/blog/12-21-2...

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