Protein Structure Evolution (ProSE) Seminar

Protein Structure Evolution (ProSe) Seminar is now on BlueSky! Every 2nd Tuesday, 4PM GMT. Sign-Up: tinyurl.com/prose-seminar2 Organized by Claudia Alvarez Carreño, Zachary Ardern, Lars Eicholt, Carolina Sanchez-Rocha, Sergio Romero Romero and Md. Hassan Uz-Zaman.

We are recruiting!! EU-funded PhD position to study the evolution of small proteins - from noise to function Apply before Oct 22 albagroup.researchmar.net/positions www.orfeus-dn.eu @grib-barcelona.bsky.social @prbb.org @researchmar.bsky.social @official-smbe.bsky.social @sciencehr.bsky.social

Join us next Tuesday, 5PM CET for ProSE! Birte Höcker will talk about testing protein evolution via protein design! 🧬 tinyurl.com/prose-seminar2

Join us next Tuesday, 5PM CET for our first ProSE after the summer! Betül Kaçar @kacarlab.bsky.social will talk about the origin and early evolution of ancient proteins! 📜🧬 tinyurl.com/prose-seminar2

@timothyfuqua.bsky.social & @vakirlis.bsky.social formalize “emergence bias” as the molecular predisposition that, upon mutation, biases a genetic sequence toward or against manifesting new or latent functions or phenotypes 🔗 academic.oup.com/gbe/article/... #societyjournal #genome #evolution

Join us the last time before the summer break! Cesar A. Ramirez-Sarmiento will talk about "Unveiling the fold-switching behavior of RfaH: echoes of the past, signals of the present". As always, Tue 5PM CET, follow the link to sign-up: tinyurl.com/prose-seminar2

Join ProSe next week Tuesday, when Noelia Ferruz @noeliaferruz.bsky.social is talking about "Controllable Protein Design with Protein Language Models and Reinforcment Learning", TUE, May 12, 5PM CET! Sign-up here: tinyurl.com/prose-seminar2

Come listen to my talk about how enhancers evolve and how promoters emerge from randomly synthesized DNA sequences!

Our next speaker will be Timothy Fuqua @timothyfuqua.bsky.social with "The Evolution and Emergence of Regulatory DNA", 14th April, 5PM CET. Sign-up here: tinyurl.com/prose-seminar2

Our next Talk will be "Protein Origami and the Hidden Rules of Functional Innovations"! March 11th, 5PM CET. Sign-up here: tinyurl.com/prose-seminar2

ProSe goes into the 2nd with a talk by Vyacheslav Tretyachenko on the pervasive alternative translation in the human proteome. Join us tomorrow via Zoom, 4PM GMT, 5PM CET.

Next up in our ProSE seminar series: Vyacheslav Tretyachenko on alternative translation in the human proteome Register to join: tinyurl.com/prose-seminar2 Past seminars: tinyurl.com/ProSE-videos

New review out in Nat Rev Genet: Emergence & evolution of protein-coding de novo genes by Erich and Lars Eicholt @lacholt.bsky.social. How non-coding DNA becomes translated, persists or is lost in populations, and can yield structured/functional proteins—plus methods & open questions! rdcu.be/e09SM

🚀We’re excited to share our new paper in Bioinformatics! We introduce a user-friendly toolkit that implements our novel DeNoFo file-format for standardised annotation of de novo gene detection workflows — enabling reproducible methodology descriptions and easier dataset comparison across studies.

Join us tomorrow! Joana Pereira is talking about AI-powered classification and discovery across the protein universe. @joanampereira.bsky.social 5PM CET, link in the post and in our bio.

The next ProSE Seminar will be given by Joana Pereira @joanampereira.bsky.social (VIB, KU Leuven) 🗓️ November 11th, 5pm CET Registration is now open: tinyurl.com/prose-seminar2 Please share!

The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU): Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t” Date: October 14th, 5 pm CET Registration link: tinyurl.com/prose-seminar2