Keith Robison

Keith Robison

@omicsomics.bsky.social

Computational biologist & blogger

3.5K followers389 following474 posts

Keith Robison
@omicsomics.bsky.social

An abundance of autumn splendor in Montreal today on the campus of The Université du Québec à Montréal (UQAM) My University of Delaware hat is in the spirit of the season, even if doesn’t quite match the tree above Looking forward to seeing past friends and meeting new ones at #ASHG26 #ASHG

Keith Robison
@omicsomics.bsky.social

What Instrument Protocol Did I Actually Use? Complex protocols for individual instruments, such as PCR profiles for thermocyclers, are often saved to instruments. But how do you know the protocol you wanted is the one you requested? omicsomics.blogspot.com/2026/09/what...

omicsomics.blogspot.comWhat Instrument Protocol Did I Actually Use?Puttering around with some ideas for future experiments on our autonomous lab, I realized a potential software engineering gap that in my ve...

Keith Robison reposted

Bart⚓️
@bartgonnissen.bsky.social

The Facial Expressions of Tethys by artist Julius von Bismarck. A suspended high-sea buoy that moves in real time. Sensors on a twin buoy out in the Atlantic Ocean send live satellite data to motors inside the museum. This makes the indoor buoy copy the exact, real-time movements of the ocean waves.

Keith Robison
@omicsomics.bsky.social

Sequence That Moldy Lanternfly! Spotted lanternflies are an imported pest that threatens orchards & vineyards, but indigenous fungi are fighting back - and several of these species have poor genome assemblies or none at all. omicsomics.blogspot.com/2026/09/sequ...

omicsomics.blogspot.comSequence That Moldy Lanternfly!Googling on some keywords from a social media post led to an interesting PNAS article from 2019 on two fungi which can infect the spotted la...
Keith Robison
@omicsomics.bsky.social

Recombination-Based Autonomous Protein Structure-Function Search My notes on a recent lab-in-a-loop preprint with an interesting approach to avoid the expense & time of many rounds of DNA synthesis omicsomics.blogspot.com/2026/08/reco...

omicsomics.blogspot.comRecombination-Based Autonomous Protein Structure-Function SearchAn interesting preprint showed up last week in the autonomous agent-driven experimentation space - an area I'm paid to be very interested in...
Keith Robison
@omicsomics.bsky.social

Come hear my talk, Tuesday 10am in session 17, Harnessing AI to Accelerate Industrial Microbiology: Driving Discovery, Optimization, and Scale-Up I’m 17-4 - Decoupling experimental design from execution with autonomous laboratories to enable human and agentic scientists

Keith Robison reposted

Chenxin Li, PhD
@chenxinli2.bsky.social

That’s just awesome

Jeff Groh@jeffgroh.bsky.social

Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...

pnas.orgBalanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNASIn avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...

Keith Robison reposted

Stirling Churchman
@stirlingchurchman.bsky.social

RNA-seq tells us how much RNA is present in the cell. But to understand gene regulation, we need to easily measure the synthesis and decay rates driving this abundance. We introduce AIR-seq: analog intrinsic recoding sequencing. (1/6) www.biorxiv.org/content/10.6...

biorxiv.orgAnalog intrinsic recoding measures RNA dynamics without chemical conversionSteady-state RNA abundance measurements mask the synthesis and decay rates that shape gene expression. Analog intrinsic recoding sequencing (AIR-seq) repurposes the base-pairing properties of N4-hydro...

Keith Robison reposted

Emily Lakdawalla 🏳️‍⚧️ Uranus Expert
@elakdawalla.bsky.social

A fun image processing distraction today -- how to clean up the noisy background of a photo of a microfilm of a medieval manuscript? Thread, in which I use Photoshop, but similar tools are available in GIMP and other image processing software.

Dr. Erika Graham-Goering@jeanneologist.bsky.social

Got a bit of a range in quality, though much of the same type—the first picture is more or less usable, the second is tough going (especially because a lot of the words are abbreviated, so it's important to see details).

Keith Robison reposted

Vivek Mutalik
@vivekmutalik.bsky.social

📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

Keith Robison
@omicsomics.bsky.social

$44/gene enzymatic function test with just $799 assay configuration!!! ~$5K & we will boot your assay & run full 96 well plate experiment! How many enzymatic reactions does this entice you to deorphan?

Keith Robison
@omicsomics.bsky.social

Less than two weeks until #AGBTAg26 ! Looking forward to planting @Ginkgo flag there - may many productive discussions bloom around autonomous laboratories and cloud lab services!

Keith Robison reposted

Jeff Gentry
@geoffjentry.bsky.social

Replying to @omicsomics.bsky.social

They had one a long time ago. About 15 years or so ago I played around with something in R to pull down data via API. It was half baked even then, guess they decided ti unbake it altogether

Keith Robison reposted

Igor Martayan
@imartayan.bsky.social

Replying to @imartayan.bsky.social

2. I don't mind if people don't want to use Rust but instead of rewriting it from scratch every single time, why don't you write bindings and make them available for everyone? This is both easier and more maintainable, and would actually be helpful for the community.