Oxford Nanopore

The quality of a gene therapy depends on the RNA that guides it. In our webinar, learn how Genentech uses direct RNA sequencing to assess mRNA and sgRNA quality attributes in a single assay and link impurities to editing efficiency in cell-based systems. https://bit.ly/4sxD5hC

Families with an unexplained rare disease can wait years while a variant stays uncertain. A University College London team built RAPID, a research workflow using nanopore technology, that produced findings in six unsolved cases within two days. https://bit.ly/4zCISVn

This week we announced the appointment of Sebastian Kronmueller as Chief Business Development Officer (CBDO), effective 4 January 2027. Sebastian joins from Philips and will lead Oxford Nanopore's strategy and business development functions Read more: https://bit.ly/4yBXSle

Maria Reyes Capilla-Guerra at Dana-Farber Cancer Institute used #AdaptiveSampling to develop a 264-region acute leukaemia research digital panel enabling methylation-based classification & variant detection from the same run. https://bit.ly/48daVPk #WeRunIt #ashg2026 RUO

Go with the gold standard for #methylation calling. Oxford #Nanopore sequencing provides best-in-class 5mC detection directly from native DNA, with no bisulfite conversion or additional sequencing runs. Learn more: https://bit.ly/3W1DOeH #WeRunIt #ASHG2026

Discover Mahi-mahi: a tool that captures and phases repeat expansion lengths, motifs, sequence interruptions, and methylation in a single assay. https://bit.ly/4iiJmsH #WeRunIt

Your next discovery is in today's run. Find out more at our industry session today at #ASHG2026. Learn more: https://nanoporetech.com/about/events/conferences/ashg-2026?utm_campaign=ASHG26&utm_content=1792603214&utm_medium=social&utm_source=bluesky Booth 901 #WeRunIt

There's more to a repeat than length. This preprint introduces Mahi-mahi, a tandem repeat genotyper for nanopore sequencing data that reports repeat length, motif composition, interruptions and methylation from the same sequencing data. https://bit.ly/4yySdww Research Use Only

André Reis from the Garvan Institute of Medical Research shares how using #AdaptiveSampling found likely causes in 41% of unsolved spastic ataxia research study cases, with DNA changes and methylation read together in one go. Learn more: https://bit.ly/4i9VAUp #WeRunIt #ASHG2026

Your next discovery is in today's run. At #ASHG2026, hear how researchers are moving beyond isolated variant detection towards comprehensive, haplotype-resolved multiomic insight, and how this could bring precision genomics into practice today. https://bit.ly/4rwhh5o #WeRunIt

Your run starts here. At #ASHG2026, learn how Adaptive Sampling lets you define, target and enrich while you sequence, no fixed panel required. See how those same reads provide gold-standard methylation and a low-pass whole genome. https://bit.ly/4hUtsG3

#ASHG2026 is just around the corner. Next week we'll show you what is already possible in a single run, from reimagining targeting sequencing with #AdaptiveSampling to a new gold standard in #methylation calling. Your next discovery is in today’s run. https://bit.ly/4s5MHzI

A prospective study from GOSH & GSTT, featured on BBC News, brought rapid respiratory #metagenomics into #paediatric intensive care, with results available the same day. BBC News: https://www.bbc.co.uk/news/articles/cw5yn83m8gypo Oxford Nanopore products are for RUO

100 million people in Africa live with rare diseases — most uncharacterised. At Stellenbosch University, nanopore sequencing has the potential to change that, delivering faster answers and bringing equitable access to genomic medicine closer to reality.

Our monthly round-up of nanopore sequencing research is out, covering brain tumour classification, rare disease trio sequencing and gene dosage in psychiatric disease. https://bit.ly/4jlYrvK

This guide introduces solutions that can be used from biomarker discovery through final product quality control (QC) testing, consolidating multiple legacy assays into one platform and enabling faster, more confident decision-making. Learn more: https://bit.ly/46ENk9D

Not all biological answers lie in the DNA sequence. In this knowledge exchange, we explore how gold-standard Oxford Nanopore methylation sequencing reveals hidden insights that traditional methods miss—all from a single run. https://bit.ly/4j7E45j

At #ASHG2026, Cristina Gamba & Philipp Rescheneder show how long nanopore reads and dedicated tools resolve repeat expansions and allele-specific variation in genomic regions that standard approaches often can't reach. https://bit.ly/4hLWlms

Abstract submission for London Calling 2027 is now open! Submit an abstract for a chance to present your breakthroughs and real-world impact at the largest nanopore sequencing conference of the year. Check out last year's video to see what it's all about. https://bit.ly/3TKd69E

Antibody development, end-to-end with one solution. Antibody discovery involves screening, confirming and characterising at multiple stages, and nanopore sequencing can support all of them. See how Pfizer has been applying this across their own workflow: https://bit.ly/4AlvF4t

See the targets you need and the biology you didn't expect. At #ASHG2026, Ellie Juarez & Miguel Reis show how Adaptive Sampling is reimagining targeted sequencing by letting you define, target, and enrich while you sequence - with no fixed panel required. https://bit.ly/4dR8LYW

What if you could see RNA exactly as it exists in the cell? Discover how direct RNA Oxford Nanopore sequencing captures transcripts without conversion or amplification, revealing biology that might otherwise be missed. Find out more: https://bit.ly/4x7PBF3

Join researchers from Jessa Hospital and Tampa General Hospital who will share their clinical research workflow considerations, validation data, and implementation insights using nanopore sequencing and BugSeq analysis for fungal pathogen ID. https://bit.ly/4hgzpeS RUO

At our Industry Education Session at #ASHG26 we'll share the latest updates on nanopore sequencing before Debarshi Mustafi shows how technology resolves difficult variants in inherited retinal disease and retinoblastoma. Learn more: https://bit.ly/4dnfGcl

Wastewater plants are vast tanks of bacteria doing humanity’s dirtiest job, yet most have never been named. Researchers just catalogued 54K genomes across 83 plants worldwide using nanopore technology. 82% were unknown to science. https://bit.ly/3SQt01J

This #WorldAnimalDay, we’re highlighting researchers around the world who are using genomics to better understand, monitor and protect vulnerable species. Learn more about the ORG.one project here: https://bit.ly/4xplkCs

At #nanporeconf, Dr. Chanatjit Cheawsamoot made the case that long-read sequencing is ready to leave the academic bubble. In Thailand, her team is already using it alongside current tests to identify variants in rare disease patients that might otherwise be missed. For RUO.

85% of childhood cancers are curable, yet global survival rates are 20%. Nickhill Bhakta shares how the DIVIA consortium is exploring the potential of adaptive sampling to democratise access to better cancer characterisation and treatment globally. https://bit.ly/4jhbChk

This is ORG one. Find out more: https://nanoporetech.com/oo?utm_campaign=AnythingAnyoneAnywhere&utm_content=1791019500&utm_medium=social&utm_source=bluesky

See more biology with gold-standard methylation calls. In our benchmarking, the Oxford Nanopore confidently called ~10% more CpGs than Illumina bisulfite sequencing. https://bit.ly/4d6vKiq

Delayed answers & missed pathogens can be fatal for those with uterine infections. Researchers are exploring the potential of nanopore sequencing to rapidly characterise pathogens that other methods miss. https://bit.ly/4d0dyXI

Today we published a new report building on discussions with over 50 leaders from #healthcare, #research and industry at our recent Health Summit in Singapore. Learn more: https://bit.ly/4rELFdD

We're proud to join @GeneticAlliance's global rare disease programme, RISE, helping expand access to genomic testing for families with unresolved genetic conditions and supporting evidence generation for nanopore sequencing. Learn more: https://bit.ly/4hsY6WR

At #ASHG2026, Cora Vacher opens our Industry Education Session on Adaptive Sampling and multiomic insight, before Debarshi Mustafi shows how long reads resolve difficult variants in inherited retinal disease and retinoblastoma. https://bit.ly/4xMOo6B

Everyone should have access to healthcare, even in remote regions. In the #nanoporeconf studio, Robert A. Edwards shared how portable nanopore sequencing has the potential to address gaps, making genomics more accessible to everyone.

Rapid answers could make a real difference for people facing a brain tumour diagnosis. A new NHS pilot is expanding rapid genomic classification across England, with the ambition to build a joined-up approach & bring potential benefits to more patients. https://bit.ly/4jmZHOX

On-the-spot pathogen identification. From initial characterisation of genomes to the rapid identification of variants, portable and accessible nanopore technology enables quick responses to public health emergencies globally. See what you're missing. https://bit.ly/4ArKtyk #WYMM

In precision oncology, time matters. See how real-time genomic and methylation insights with nanopore sequencing has the potential to help classify cancer faster, enabling a future where rapid, informed treatment decisions could be a reality. Watch here: https://bit.ly/4cKa2k8

On October 21, Pfizer will share how they replaced outsourced workflows across antibody discovery, plasmid verification, and cell-line characterisation, with Oxford Nanopore sequencing. Register here: https://bit.ly/4AlvF4t

Take your research to the next level with gold-standard methylation sequencing. Oxford Nanopore delivers the highest-accuracy 5mC calling of all methods benchmarked. See the full dataset here: https://bit.ly/4xy1c0s

This World Alzheimer’s Day, we’re highlighting researchers working to understand the biology behind this complex disease. Read how Kim Billingsley & her team are decoding the human brain to better understand the mechanisms behind neurodegeneration: https://bit.ly/4zLcq40

86 malignancy types. Over 98% accuracy among classified research samples. A confident call within minutes of sequencing. New preprint demonstrates the potential of a nanopore-based methylation classifier for hematologic malignancy research. https://bit.ly/4cGDdEw

"2 to 6 weeks" for molecular classification vs. hours with Oxford Nanopore sequencing. Min Sun Park (@UW) on why turnaround time isn't just a technical detail — it's a human one. RUO Learn more: https://bit.ly/4y1LX0V

Developing cell and gene therapies is hard. Understanding the biology shouldn't be. By sequencing full-length DNA and RNA molecules directly, learn how Oxford Nanopore is helping researchers gain deeper insights, reduce risk, and accelerate development. https://bit.ly/4dzaxh6

This month's Science Unlocked covers adaptation to genetic bottlenecks, cell-free DNA sequencing, and microbiome research. These studies showcase the advances in scientific research made possible by Oxford Nanopore technology. Read here: https://bit.ly/4rdi4Yx

258 cancer genes. One assay. Real answers. Discover how Oxford Nanopore’s hereditary cancer panel reveals what others miss. Discover more: https://nanoporetech.com/hereditary-cancer-panel?utm_campaign=Clinical+cancer+26&utm_content=1789490701&utm_medium=social&utm_source=bluesky

New in Neuro-Oncology: researchers at Princess Máxima Center report on Sturgeon, their AI-based tool built on nanopore sequencing, used in their own paediatric neurosurgical workflow to help inform real-time surgical decisions. https://bit.ly/4y5v1pI RUO

Not all biological answers lie in the DNA sequence. In this knowledge exchange, explore how gold-standard methylation sequencing with Oxford Nanopore reveals hidden insights that traditional methods miss — all from a single run. Register here: https://bit.ly/4xoxqed

Have questions about EPI2ME? Now’s your chance to ask them! Head over to the Nanopore Community and add your questions for our EPI2ME experts to reply to them directly in the thread. Submit your questions now: https://bit.ly/4heKkqu

Unbox the world’s smallest and most accessible sequencer. The MinION Mk1D is portable yet powerful, ideal for labs looking for rapid results without compromise. Simply plug it into your laptop and start sequencing, whether in the lab or in the field. https://bit.ly/4x6HfgR