Saul Kato

Saul Kato

@focolab.bsky.social

I study things that think. Neuroscience professor at UCSF. Foundations of Cognition Lab. Reformed tech founder. www.focolab.org. https://substack.com/@saulkato

155 followers158 following25 posts

We noticed that a plate of C. elegans worms, under starvation conditions, forms stable living spatial structures, which we dub "worm webs". These webs seem to be scaffolded by an excreted substance from living or dead worms, which we dub "wormstuff". www.focolab.org/post/worm-we...

focolab.orgWorm Webs and WormstuffSometimes a fresh pair of eyes in a lab notices a phenomenon that has been under the noses of researchers for a long time but ignored as a distraction. After more careful observations, replications, a...

We built StarDist to detect cells in volumetric microscopy and jointly infer closed curved parametric surfaces for each cell. It's an example of an interpretable machine learning approach. More detail in the blog post and preprint. www.focolab.org/post/surfdis...

focolab.org"SurfDist" pre-print postedWe developed an "interpretable machine learning" system to find and characterize blobs in volumetric images, such as microscopy images of cells, something we need to do all the time in our lab. The no...

An instant classic by Zheng and Meister ‪(@mameister4.bsky.social‬): www.cell.com/neuron/fullt... "...1⁢0^8... the ratio between peripheral information processing and the overall throughput of the brain. Numerically speaking, this may be the largest unexplained number in brain science. "

cell.comThe unbearable slowness of being: Why do we live at 10 bits/s?Zheng and Meister write about the paradoxical slowness of human behavior. Although our senses gather data at 109 bits/s, our overall information throughput is only 10 bits/s. This stark contrast touch...

Data contamination (validation data leaking into training data) is a critical problem for the whole approach of (static) performance benchmarks to test large AI models. This issue needs to be surfaced more. This article for example, completely neglects it. www.nytimes.com/2025/01/23/t...

nytimes.comWhen A.I. Passes This Test, Look OutThe creators of a new test called “Humanity’s Last Exam” argue we may soon lose the ability to create tests hard enough for A.I. models.

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