Dunn Lab (@dunnlab.bsky.social)

Dunn Lab

@dunnlab.bsky.social

We study how living things build themselves. Core approaches are molecular biophysics and cryo-ET. We also work closely with developmental and computational biologists. Will post about new results, relevant meetings, and cool papers from collaborators.

153 followers 51 following11 posts

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Dunn Lab

@dunnlab.bsky.social

15 Jan

Mark your calendars, the Signaling by Adhesion Receptors GRC is June 7 - 12, 2026. We have a terrific program that balances developmental biology, cell polarity, and adhesion and signaling. Please spread the word! www.grc.org/signaling-by...

grc.org2026 Signaling by Adhesion Receptors Conference GRCThe 2026 Gordon Research Conference on Signaling by Adhesion Receptors will be held in Manchester, New Hampshire. Apply today to reserve your spot.

Dunn Lab

@dunnlab.bsky.social

7 May

A reminder that the registration deadline for the Signaling by Adhesion Receptors GRC is May 10, just a few days from now. Hope to see you there, and please pass along to anyone you think would be interested. www.grc.org/signaling-by...

Dunn Lab

@dunnlab.bsky.social

29 Apr

Protein language models like ESM3 make it possible predict and design protein structures, but 1/3 of our proteome is unstructured. In collab. w/ Grant Rotskoff @grant.rotskoff.cc, Jason Liu created a PLM tuned specifically to generate biologically realistic IDRs: www.biorxiv.org/content/10.6...

biorxiv.orgbiorxiv.org

Dunn Lab

@dunnlab.bsky.social

29 Apr

This model provides a potentially powerful means to discover new rules that dictate IDR biological function, and to design unstructured proteins for engineering applications. The model itself has features that may appeal to ML aficionados as well. Try it for yourself! idiom-design.vercel.app

idiom-design.vercel.appidiom-design.vercel.app

Dunn Lab

@dunnlab.bsky.social

29 Apr

12 days to submit abstracts and register for the Signaling by Adhesion Receptors GRC, held June 7 - 12, 2026 in scenic New Hampshire! We have a terrific program that balances developmental biology, cell polarity, and adhesion and signaling. www.grc.org/signaling-by...

grc.orggrc.org

Dunn Lab reposted

Mark Peifer (He, him)

@peiferlabunc.bsky.social

13 Mar

Apply now for the Signaling by Adhesion Receptors GRC June 7 - 12, 2026! The meeting has a terrific program that balances developmental biology, cell polarity, and adhesion and signaling. Please share! www.grc.org/signaling-by...

Dunn Lab reposted

matt-dejong.bsky.social

@matt-dejong.bsky.social

27 Feb

First preprint of the @pollyfordyce.bsky.social and @dunnlab.bsky.social collaboration! We used high-throughput microfluidics for sequence-strength mapping at the single-molecule level. Our new tech allowed us to discover a fundamental nonequilibrium property of multivalent systems. 1/13

Dunn Lab

@dunnlab.bsky.social

2 Mar

Big congrats to @matt-dejong.bsky.social on his preprint! Matt's assay increases single-molecule biophysics throughput ~100x relative to typical approaches. This delightful collaboration with @pollyfordyce.bsky.social lab helps bring biophysics into the 'omics era. tinyurl.com/yvs54jds

With help from Danelle Devenport and Jessica Feldman, Maddy and I are making the conference a home for the cell polarity community. The scientific synergies are obvious, and I'm excited to see these two communities together.

Dunn Lab

@dunnlab.bsky.social

31 May 2025

I'm helping organize the 2026 Signaling by Adhesion Receptors GRC and would love your speaker suggestions! We're especially looking for assistant professors or new community members who would enrich the meeting. Send your suggestions via PRIVATE message or email. Thanks!

Dunn Lab

@dunnlab.bsky.social

22 May 2025

Please consider applying to this fabulous Company of Biologists Meeting! New Technologies for Studying and Reprogramming Development 16 – 19 November 2025, Buxted Park, East Sussex, UK COB meetings are amazing: small, focused, and with exceptional speakers (food and drink are also exceptional)!

Dunn Lab

@dunnlab.bsky.social

12 Jan 2025

1st catch-up post: Christina (now faculty, UCSD) used single-molecule imaging and theory to understand the mechanism of motility used by Apicomplexans, single-celled parasites that includes malaria. Read for: unusual cytoskeletal dynamics, active-matter theory www.nature.com/articles/s41...

nature.comEmergent actin flows explain distinct modes of gliding motility - Nature PhysicsUnicellular parasites, such as Toxoplasma gondii, can use different forms of gliding motions when infecting a host. These motility modes arise from the self-organizing properties of filamentous actin ...

Dunn Lab

@dunnlab.bsky.social

11 Jan 2025

Hello world! We're happy to be moving our account to a new platform. Over the next few days I'll be posting a backlog of news from our group.

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