Jon Lim, FRCP PhD

Jon Lim, FRCP PhD

@drjonlim.bsky.social

Senior Lecturer & Consultant Medical Oncologist in Advanced #Immunotherapy + #CellTherapy at @manchester.ac.uk & The Christie • RISE Lead & MANIFEST Deputy Lead • ESMO #TranslationalResearch Faculty 🔗 Bio: bit.ly/Christie_JLim (tennis enthusiast 🎾)

2.4K followers540 following493 posts

Pinned

My main PhD paper is finally out! 🎉 After ~5 years, it’s published today in 𝘕𝘢𝘵𝘶𝘳𝘦 𝘐𝘮𝘮𝘶𝘯𝘰𝘭𝘰𝘨𝘺. @natimmunol.nature.com It all started with an unexpected observation 🔍: 👉 Mice lacking the dendritic cell receptor DNGR-1 developed tumours earlier ⏩ and more frequently 📈 than wild-type mice. 1/11 🧵

Attending #ESMO26? 📲 Have you checked out the App? Here’s a useful guide, especially for those who have not used it before - there’s a video demo in the link below 👇 #ESMOAmbassadors

Attending #ESMO26? 📱Download the ESMO Events App to browse the programme, save your must-attend sessions and create your personalised agenda before you arrive. A simple step to help you make the most of your congress experience from day one. 🔗 https://ow.ly/7ycy50ZZXgI

The countdown to #ESMO26 begins… looking forward to seeing many colleagues and friends in Madrid 🇪🇸, and the practice-changing data that will be showcased. #ESMOAmbassadors @myesmo.bsky.social

Presidential Symposium I at #ESMO26 #Melanoma, #bladder, #lung and #prostate cancers: late-breaking data that can change clinical practice across diseases. ➡️ https://ow.ly/z1el50ZYpGo @fandremd.bsky.social

🐝 Celebrating 1️⃣ year of Prof Samra Turajlić leading @cruk-mi.bsky.social, marked by our inaugural The Christie Ignite Lecture. Bringing scientists and clinicians together to ask: “𝘞𝘩𝘢𝘵 𝘤𝘰𝘶𝘭𝘥 𝘸𝘦 𝘥𝘰 𝘵𝘰𝘨𝘦𝘵𝘩𝘦𝘳?” Big questions. Shared ambitions. Patients at the heart. Thank you, Samra! #TeamScience

🧑‍🔬 𝗜𝗻𝘁𝗲𝗿𝗲𝘀𝘁𝗲𝗱 𝗶𝗻 𝗰𝗮𝗻𝗰𝗲𝗿 𝗶𝗺𝗺𝘂𝗻𝗼𝗹𝗼𝗴𝘆? 𝗟𝗼𝗼𝗸𝗶𝗻𝗴 𝗳𝗼𝗿 𝗮 𝗣𝗵𝗗 𝗼𝗽𝗽𝗼𝗿𝘁𝘂𝗻𝗶𝘁𝘆? We're looking for a clinician to join us in Manchester to explore “𝗶𝗺𝗺𝘂𝗻𝗲 𝗳𝗶𝘁𝗻𝗲𝘀𝘀” - how cancer tx, ageing & comorbidities shape immunity + what this means for response, toxicity & recovery. @mcrcnews.bsky.social 🔗 Further info:

crukcentre.manchester.ac.ukDefining immune fitness in cancer: how cancer treatment and comorbidity shape systemic immunity - Cancer Research UK Manchester CentreClinical Research Training Fellowship. Applications now open.

𝗦𝘂𝗽𝗲𝗿𝘃𝗶𝘀𝗼𝗿𝘆 𝘁𝗲𝗮𝗺: Dr Jonathan Lim, Prof Samra Turajlić, Prof Mark Travis, Prof Omer Aziz, Prof Magnus Rattray and Dr Elizabeth Appleton. 🌍 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗣𝗵𝗗 𝗙𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽 - 3 years; outstanding applicants from outside the UK welcome 🗳️ Apply by 23 Nov 2026 @cruk-mi.bsky.social @uom-dcs.bsky.social

Great to be here in Suzhou 🇨🇳 this week for #CSHAsia Cancer Immunotherapy meeting. Looking forward to learning from colleagues and discussing science 👇

#CSHAsia #CancerImmunotherapy #Immunology #CancerResearch Join us this September for the CSHA Symposium on Cancer Immunotherapy! 👉 Submit your registration: www.csh-asia.org?content/2986

Jon Lim, FRCP PhD reposted

Welcome, Professor Mahima Swamy! 💜 An internationally recognised researcher in intestinal immunology, Professor Swamy has joined the University of Manchester's Lydia Becker Institute as Professor of Immunology, strengthening its world-class expertise in barrier immunity.

Jon Lim, FRCP PhD reposted

As an early-phase trialist, I never stop being amazed by the bravery & generosity of people who step forward into the unknown. Patients like Tracy don't just shape their own care; they open doors for everyone who follows. 🔬 So it means a great deal to share a 𝗴𝗹𝗼𝗯𝗮𝗹 𝗳𝗶𝗿𝘀𝘁 🌎... @mcrcnews.bsky.social

bbc.co.ukOldham woman becomes world's first to receive new cancer therapyTracy Tomlinson was offered the clinical trial for ovarian cancer at The Christie hospital in Manchester.

𝗭𝗜𝗠𝗔-𝟭𝟬𝟭 is a 1st-in-human, 1st-in-class TCR-NK cell therapy trial, which is a true collaboration between our Advanced IO/Cell Therapy team at The Christie & the Zelluna team. Those in the know understand how much happens behind the scenes. Setting up a cell therapy study is never straightforward.

We're still early in the trial, but this feels like the right moment to recognise the multidisciplinary team who made it possible 🙌. Fiona & I couldn't be prouder of our team. Here's to creating more opportunities for patients through research. 💙 📻 𝗕𝗕𝗖 𝗥𝗮𝗱𝗶𝗼 𝟱 𝗟𝗶𝘃𝗲 [31 Jul 2026 | 1:26:37]

🚀 A major milestone for @manifest-cirrp.bsky.social. Launching our prospective recruitment represents a significant milestone since we launched in Q4 2024. In doing so, we'll have the opportunity to learn from every patient. @ukri.org @crick.ac.uk 📖 Read more in The Christie press release: 1/4

christie.nhs.ukSandbach man is the first in the UK to join landmark immunotherapy studyMark England was diagnosed with bladder cancer in early December last year. He is the first patient to join the MANIFEST study, one of the largest immunotherapy studies in the country.
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This is only possible because of an incredible collaboration 🤝 between patients, clinicians, research teams, scientists, NHS partners, industry and funders. Thank you to everyone who has helped bring MANIFEST to this point! 4/4

🚀 A major milestone for @manifest-cirrp.bsky.social. Launching our prospective recruitment represents a significant milestone since we launched in Q4 2024. In doing so, we'll have the opportunity to learn from every patient. @ukri.org @crick.ac.uk 📖 Read more in The Christie press release: 1/4

christie.nhs.ukSandbach man is the first in the UK to join landmark immunotherapy studyMark England was diagnosed with bladder cancer in early December last year. He is the first patient to join the MANIFEST study, one of the largest immunotherapy studies in the country.

𝗠𝗔𝗡𝗜𝗙𝗘𝗦𝗧 is truly a team effort. 💡 Humbled to hear our very first patient share his perspective. Experiences like his will shape how we scale up & are already helping us learn how more. Watch this space. @manifest-cirrp.bsky.social 📰 As featured today in @theobserveruk.bsky.social 👇

observer.co.uk‘It won’t help me, but it might help someone like me’ say...Mark England says numb fingers help him play guitar as researchers hope to change how disease is treated by investigating why immunotherapy does not benefit all

🔬 Another fantastic 𝗠𝗮𝗻𝗰𝗵𝗲𝘀𝘁𝗲𝗿 𝗜𝗺𝗺𝘂𝗻𝗼-𝗢𝗻𝗰𝗼𝗹𝗼𝗴𝘆 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 (𝗠𝗜𝗢𝗡) meeting! Great to bring together colleagues from academia, NHS & industry to showcase Manchester-led immuno-oncology research, celebrate recent presentations at major international 🌍 conferences. @mcrcnews.bsky.social

Thank you to our speakers: 🎯 Prof Fiona Thistlethwaite 🎯 Dr Frances Turrell 🎯 Prof Claus Jørgensen ...and to everyone who joined us. Looking forward to building even more collaborations across Manchester's IO community.

A great collaboration 🙌 between our Thoracic Oncology, and Advanced Immunotherapy and Cell Therapy teams at The Christie 🐝 - driven by our stellar Senior Clinical Research Fellows Federico Monaca and Rachel Woodford. Available #OpenAccess in 𝘛𝘩𝘦𝘳 𝘈𝘥𝘷 𝘔𝘦𝘥 𝘖𝘯𝘤𝘰𝘭 👇 @christielibrary.bsky.social

Cytokine release syndrome (CRS) isn’t just a challenge in hematologic cancers -it’s increasingly relevant in solid tumours. This review dives into mechanism-driven strategies for prevention and management. 📖 buff.ly/ZDar0oT #Oncology #Immunotherapy #CancerResearch #ClinicalInsights

Great to be in Porto 🇵🇹 for ASPIC International Congress. Looking forward to 2 days of science! Slightly shameless plug: if you’re interested in PhD, postdoc, clinician-scientist, group leader or Clinical Research Fellowship opportunities in Manchester, come say hello 👋 - I’d be happy to chat.

Featured on BBC News: #TeamManchester is growing. 🚀 Cancer Research UK Manchester Institute will be receiving an extra £6m a year in investment, creating 8️⃣ senior research roles: 4 group leaders, 2 senior group leaders & 2 clinician scientists. @cruk-mi.bsky.social www.bbc.co.uk/news/article...

bbc.co.ukManchester cancer research lab's £6m extra annual cash boostCancer Research UK Manchester Institute says the extra cash will make a "huge difference" to its work.

🚀 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗙𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽 opportunities - come join us in Manchester! Looking to develop your career in Oncology? Interested in building a subspecialty interest? Keen to combine clinical excellence with research? Several exciting opportunities available at The Christie NHS Foundation Trust 👇

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🚀 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗙𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽 opportunities - come join us in Manchester! Looking to develop your career in Oncology? Interested in building a subspecialty interest? Keen to combine clinical excellence with research? Several exciting opportunities available at The Christie NHS Foundation Trust 👇

Jon Lim, FRCP PhD reposted

Almost 2️⃣ years in… Our MANIFEST AGM convened scientists, clinicians, patient partners & industry. Keynotes from Prof Levesque & Prof Rattray + Prof Turajlić setting the course ahead. Big thank you to all for continuing to believe in the vision; to tackle the hard questions in #CancerImmunotherapy.

💥 Really pleased to see this story finally out in @natcancer.nature.com. An elegant study built around a very cool concept. Huge congratulations to Tom Castro-Dopico, @reisesousalab.bsky.social and all colleagues involved - delighted to have played a small part in it the journey. @crick.ac.uk

Caetano Reis e Sousa@reisesousalab.bsky.social

Delighted that our paper is out @natcancer.nature.com. Research led by Tom Castro-Dopico in partnership with Adendra Therapeutics reporting on a means to increase presentation of antigens from cancer cells. Read it for free at www.nature.com/articles/s43...

Fantastic 2 days in San Diego 🌴 for the inaugural C8 Early Career Investigators Symposium. Happy to represent #TeamManchester + connect with an inspiring group 🌍. A reminder that we’re not navigating academia alone - great to hear re: lessons learned & tips for future 🤝. @mcrcnews.bsky.social