Daniel Figeys
Daniel Figeys
@dfigeys.bsky.social
Precision-function-based microbiome trials. Ex vivo microbiome assays. Microbiome–xenobiotic interactions. Meta-omics analyses
393 followers706 following44 posts
Daniel Figeys reposted
🆕 Vacancy! We’re looking for a Postdoctoral Research Scientist to investigate relationships between diet, the human gut microbiome and mental health across more than 20 European cohorts within the NUTRIMIND consortium 💷 £39,000 to £46,500 🗓️ Apply by 17 November 2026 ➡️ buff.ly/lh4ZBr0
Daniel Figeys reposted
“I’m delighted to announce Stella’s appointment as Chair from next year. Stella’s skills and experience are perfectly aligned with Quadram Institute Bioscience’s mission to bring real health and economic benefits to our society in the years ahead." 💬Our Director Professor @dfigeys.bsky.social
Daniel Figeys reposted
Replying to @wcratcliff.bsky.social
3/17 Graduate students and postdocs: we strongly encourage you to apply! The Gordon Research Seminar (GRS), organized by Noah Houpt (@noahhoupt.bsky.social) and Duhita Sant (@duhitasant.bsky.social), runs June 26–27, immediately before the GRC.
Daniel Figeys reposted
This Trustee Director role is an exciting opportunity to have significant impact on our organisation in a unique partnership between science, academia and health research, as the Institute enters a phase of significant growth and increased global impact 🗓️ Apply by 31 August 2026 ➡️ buff.ly/zmfgJLL
Wu, Zhang et al. introduce MetaTree, a browser-based platform for hierarchical data visualisation, multi-group comparison with statistical analysis. Easy to use and publication ready figures. #microbiome + #metaproteomics. doi.org/10.1186/s128...
Daniel Figeys reposted
Great to hear Science Minister Lord Patrick Vallance talk about the relevance of research organisations to UK plc at the launch of the National Research Organisations @nro-group.bsky.social tonight. quadram.ac.uk/uks-world-cl...
Daniel Figeys reposted
🆕 The National Research Organisations (NRO) Group officially launches today at Royal Academy of Sciences, London. buff.ly/R5ny8fx
Dobranowski et al. studied the response of 66 paediatric IBD microbiomes to nine resistant starches. The results were highly personalised, while multi-omics uncovered metabolites beyond butyrate and a shift from mucin degradation to starch utilisation. www.nature.com/articles/s41...
Dobranowski et al. studied the response of 66 paediatric IBD microbiomes to nine resistant starches. The results were highly personalised, while multi-omics uncovered metabolites beyond butyrate and a shift from mucin degradation to starch utilisation. www.nature.com/articles/s41...
Our earlier work with six structurally distinct oligosaccharides showed that microbiomes share broad responses—such as prioritising dietary fibre over mucin—but the microbes and enzymes involved can differ markedly between individuals. www.nature.com/articles/s41...
Our latest preprint extends this picture: among 18 healthy donors across three age groups, both oligosaccharide structure and donor age shaped microbiome function. Even closely related glycans produced distinguishable responses. doi.org/10.64898/202...
Daniel Figeys reposted
🔬 South Norfolk is helping shape the future. It was brilliant to visit the Royal Society and see the incredible work of the Norwich Research Park's @quadraminstitute.bsky.social, @johninnescentre.bsky.social and @earlhaminst.bsky.social on show. We should all be proud. #SouthNorfolk #Science
Daniel Figeys reposted
"The story of vitamin B12 is unusual because the body needs so little of it, yet the consequences of deficiency can be profound." 💬 Professor Martin Warren @vitaminb12lab.bsky.social in @uk.theconversation.com
New preprint led by Ailing Zhang: “Donor Age and Oligosaccharide Structure Jointly Shape the Gut Microbiome Function.” Moving toward precision prebiotics design that can be selected for different stages of life. www.biorxiv.org/content/10.6...
Tired of long lists of possible bacteria with little statistical support in metaproteomics? Wu et al. developed MetaUmbra which provides statistically evidence on which bacteria are present in a microbiome. doi.org/10.64898/202... #microbiome #metaproteomics #bioinformatics #proteomics
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🆕 Dr Aimée Parker's research on microbial modulation for healthy ageing featured in BBC Science Focus Magazine ⤵️
Daniel Figeys reposted
⏰ Closing soon We’re looking for a Research Scientist (Metaproteomics) to join Dr Kai Cheng's group to develop and apply computational and analytical methods for metaproteomics 💻️ 💷 £37,500 to £45,350 🗓️ Apply by 6 May ➡️ buff.ly/8sZPg1T
Daniel Figeys reposted
"Tell me who your friends are, and I’ll tell you who you are." It turns out, microbes follow the same rule! Very proud to share our lab's new paper in @natmicrobiol.nature.com showing that bacteria don't just respond to their environment, they respond to each other. www.nature.com/articles/s41...
🆕 Vacancy! We’re looking for a Research Scientist to join @webberma.bsky.social 's group and characterise transposon mutant libraries in Shewanella and other relevant organisms as part of the EB MIND Engineering Biology Mission Award 💷 £37,500 to £40,600 🗓️ Apply by 7 April 2026 ➡️ buff.ly/a4OQqYe
Daniel Figeys reposted
Great to hear our local MP Ben Goldsborough highlighting in Parliament the world-class science taking place here at the Quadram Institute and @johninnescentre.bsky.social on vitamin D deficiency and sunshine tomatoes🍅 We’d be delighted to host a visit by Dame Angela Eagle.
One in five people face Vitamin D deficiency. In South Norfolk, we are part of the solution. At the @quadraminstitute.bsky.social, @johninnescentre.bsky.social located at the Norwich Research Park, scientists are testing Vitamin D rich tomatoes. Learn more: quadram.ac.uk/vital-d/
Daniel Figeys reposted
🚨 A new piece of the preterm gut microbiome puzzle just fell into place! Bifidobacterium metabolise human milk oligosaccharides (HMOs) in early life — shaping immunity, supporting gut development, and protecting against diseases like necrotising enterocolitis (NEC). www.nature.com/articles/s41...
Daniel Figeys reposted
"It’s great to see @nnuh.bsky.social clinicians working with scientists at the Quadram to understand more about some of the clinical challenges they face daily, and how we can understand and then tackle them for the benefit of patients.” 💬 @dfigeys.bsky.social
Daniel Figeys reposted
⏰ Closing soon! We’re looking for an ambitious and collaborative Group Leader or Career Track Group Leader to pioneer the development of next-generation microbiome assays and model systems 💷 Competitive 🗓️ Apply by 15 February 2026 ➡️ buff.ly/W3Sphca
Daniel Figeys reposted
⏰ Closing soon! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction. 💷 £45,450 to £56,750 🗓️ Apply by 15 February 2026 ➡️ buff.ly/juVfDq7
Expert in #metaproteomics? Join the Quadram Institute and help us transform functional microbiome research. #microbiome www.nature.com/naturecareer...
If you have experience in #metaproteomics and microbiology, then this is for you!
🆕 Vacancy! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction. 💷 £45,450 to £56,750 🗓️ Apply by 15 February 2026 ➡️ buff.ly/UpcuEPa
Daniel Figeys reposted
⏰ Closing soon! We are looking for a Group Leader with a focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme as a Group Leader. 💷 Competitive 🗓️ Apply by 18 January 2026 ➡️ buff.ly/5CIkq6J
Daniel Figeys reposted
🆕 Vacancy! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction. 💷 £45,450 to £56,750 🗓️ Apply by 15 February 2026 ➡️ buff.ly/UpcuEPa
Are you interested in #metaproteomics? We have a senior scientist position in my lab focused on metaproteomics, and xenobiotic- #microbiome -host interactions. Check it out. jobs.quadram.ac.uk/Details.asp?...
Daniel Figeys reposted
Researchers from the Quadram Institute have come together to develop a new open access book filled with cutting-edge methods and protocols to ensure best practice in microbiome research.
Daniel Figeys reposted
Our latest newsletter is out now 📩 Sign up to stay up to get our latest news straight to your inbox ⤵️
Zhang et al, with the #RapidAIM assay and #metaproteomics, show that gut #microbiomes exhibit shared and individualized functional responses when exposed to six structurally distinct oligosaccharides. Functional understanding requires studying in dividual microbiome. www.nature.com/articles/s41...
Daniel Figeys reposted
“The Quadram Institute is proud to be part of the newly launched National Research Organisations (NRO) Group – uniting UK research centres to #MakingResearchMatter for people, communities & the economy." 💬 Professor @dfigeys.bsky.social
We’ve launched! 🎉 The National Research Organisations (NRO) Group unites 35 UK research organisations to provide a unified and authoritative perspective on science, policy, and research investment. Learn more: nrogroup.org #MakingResearchMatter #NROGroup
Daniel Figeys reposted
🆕 Anti-depressant drugs cause profound changes to the human gut microbiome, but these changes could be mitigated by prebiotics, according to a major new survey of how the microbial community in the gut responds to different therapeutic drugs 💊 @dfigeys.bsky.social buff.ly/uKd5PDv
Daniel Figeys reposted
Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism www.cell.com/neuron/fullt...
Functional redundancy matters: the more overlapping microbial functions you have, the more resilient your #microbiome. We showed a strong negative correlation between redundancy loss and increase in #antimicrobial resistance protein upon #drug treatment of microbiomes. @quadraminstitute.bsky.social
Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs. @quadraminstitute.bsky.social rdcu.be/eMmcT
Interestingly, #drugs for the nervous system (antidepressants/antipsychotics) stand out: #SSRI/ #SNRI/ #TCA push the gut #microbiome into alternate states, lowering functional redundancy(lower capacity to respond) and ramping up antimicrobial-resistance proteins. @quadraminstitute.bsky.social
From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too. rdcu.be/eMmcT
Daniel Figeys reposted
1 in 5 people in the UK are estimated to be deficient in #vitaminD during winter and spring 📉 Our ViTaL-D Study aims to understand whether tomatoes biofortified through gene-editing tomatoes to be high in vitamin D leads to higher levels of active vitamin D in the blood 🍅 ➡️ buff.ly/SIsELo6
From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too. rdcu.be/eMmcT
Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs. @quadraminstitute.bsky.social rdcu.be/eMmcT
Daniel Figeys reposted
We were delighted to welcome Sir Ian Chapman the new CEO of @ukri.org , together with BBSRC representatives, to Norwich Research Park today hear about our world leading bioscience. Discover more about our research at the Quadram Institute ➡️ buff.ly/NZYHB2r
Daniel Figeys reposted
Exposure to sugar early in life: a natural experiment among >63,000 @uk_biobank participants: rationing of sugar was associated with less cardiovascular risk in adulthood www.bmj.com/content/391/...
Daniel Figeys reposted
“This study is particularly important to me as it took place during my post doc years at the @uniofeastanglia.bsky.social and it has been a source of inspiration for my current research line, as a newly appointed Early Career Fellow at the Quadram Institute." 💬 Dr Serena Monaco
Daniel Figeys reposted
“Vitamin D deficiency represents a significant public health concern, especially during the winter months with significant deficiency across the UK population." 💬 Professor Martin Warren, our Chief Scientific Officer
Daniel Figeys reposted
Maternal emulsifier consumption alters the offspring microbiota leading to long-lasting diseases susceptibility www.nature.com/articles/s41... Consumption of food additives during pregnancy alters offspring gut microbiota and increases inflammatory disease risk medicalxpress.com/news/2025-09...
This is an exciting position that will shape the direction of how we target the gut microbiome. Come join my lab at the Quadram Institute.
🆕 Vacancy! We're looking for a Senior Research Scientist to advance precision prebiotic microbiome intervention trials to study the interactions of prebiotics, drugs and other xenobiotics on the gut microbiome. 💷 £45,450 to £56,750 🗓️ Apply by 2 October 2025 ➡️ buff.ly/BQKamDW
Interested in compound- microbiome interactions, and how they affect health? Join my lab at the Quadram Institute.
🆕 Vacancy! We're looking for a Research Scientist (Xenobiotics) to investigate xenobiotic–microbiome interactions and understand the variation in responses across different individual microbiomes. 💷 £37,500 to £45,350 🗓️ Apply by 2 October 2025 ➡️ buff.ly/8abEye5