Developmental Biology

Our next DevBioConnect Author Seminar is on November 11th, 2026, Wednesday, 12:00–13:00 EST Dr. Ji-Hye Yea On gene regulatory network on synovial joint development Dr. Mark Emerson On transcriptomics of developing retina in little skate Register here👇 forms.gle/PhuVGA8g4cwZ...

Today😆 October 14, 2026 12:00–1:00 PM EST DevBioConnect Author Seminar Dr. Heer Joisher 🐥 Retina photoreceptor patterning www.sciencedirect.com/science/arti... Dr. Nathan Anderson 🪰 Neuronal lineage specification www.sciencedirect.com/science/arti... Register here👇 forms.gle/oPAyTEnRU8Ny...

Our next DevBioConnect Author Seminar is on October 14th, 2026 12:00–1:00 PM EST Dr. Heer Joisher On Chick🐥 Retina photoreceptor patterning Dr. Nathan Anderson On Drosophila🪰 Neuronal lineage specification Register here👇 forms.gle/oPAyTEnRU8Ny... @socdevbio.bsky.social

#DBfeature #LatestResearch 🐠👁️ Regenerated fish retinas are similar to undamaged retinas, but display local patterning errors in comparison with undamaged retinas; new models could test their functionality recovery. By Deborah L. Stenkamp doi.org/10.1016/j.ydbio.2026.07.009

#DBfeature #ICYMI Ascidian Botryllus humilis is capable of whole-body regeneration, becoming a promising new model for aging and stem cell dynamics. By Arzu Karahan doi.org/10.1016/j.ydbio.2025.10.002

#DBfeature #LatestResearch 🧠 Neural crest marker FOXD3 regulates ventralising SHH expression in the floorplate and is required for proper neural tube morphogenesis. By Jenaid Rees, Laura Kerosuo, et al. doi.org/10.1016/j.ydbio.2026.07.001

#DBfeature #ICYMI Sfrp1a regulates hematopoietic stem and progenitor cell development and canonical Wnt signaling in a dose-dependent manner in zebrafish. By Amber Ide, Stephanie Grainger, et al doi.org/10.1016/j.ydbio.2025.09.019

#DBfeature #LatestResearch 🧠 A central role for Islr2 in direct pathway striatal projection neurons for the correct formation of the internal capsule and cerebral peduncle By S Ali, J Ehrman, P Merchan-Sala, M Kofron, R Waclaw, K Campbell doi.org/10.1016/j.ydbio.2026.07.003

#DBfeature #ICYMI 🐠 Conserved genes play a role in facial soft tissue morphogenesis in humans and cichlids. By Ehsan Pashay Ahi, Christian Sturmbauer, R. Craig Albertson, Pooja Singh doi.org/10.1016/j.ydbio.2025.10.014

#DBfeature #LatestResearch Thyroid-hormone-induced metamorphosis has been deregulation in the evolution of obligately paedomorphic salamanders By Ronald Bonett, Samantha Trame doi.org/10.1016/j.ydbio.2026.06.009

#DBfeature #ICYMI 🐠 Overexpression of potassium channel Kcna5 alters skeletal patterning in the zebrafish regenerating fin, delaying joint formation and causing longer segments. By Alexander Seaver, Xinxhao Li, Kathryn Iovine tinyurl.com/ut5wyx2v

#DBfeature #LatestResearch The oocytes of basal dermapterans (earwigs) lack the posterior pole lysosomal compartment By Szczepan Bilinski, Magda Sochaczewska, Paula Irles, Stanislaw Miodonski, Andres Sarrazin, Waclaw Tworzydlo doi.org/10.1016/j.ydbio.2026.07.002

Today! September 16th 2026 EST: 12:00–1:00 PM New season of DevBioConnect Author Seminar begins on Dr. David Paulding On Cranial Neural Crest www.sciencedirect.com/science/arti... Dr. Neha Ahuja On Renal Pericyte www.sciencedirect.com/science/arti... Register here👇 forms.gle/m14hJGbU2V8c...

#DBfeature #ICYMI Mouse variants in Taf1c - a crucial component of the RNA polymerase I pre-initiation complex - result in reduced survival to birth By Jennifer Watts, Logan Willeke, Rolf Stottmann tinyurl.com/yr7bne74

#DBfeature #LatestResearch Branch extension and intracellular lumen formation are spatio-temporally coupled throughout Drosophila larval stages, and nascent tubes are initially fluid-filled By Tanner Simpson, Jodi Schottenfeld-Roames doi.org/10.1016/j.ydbio.2026.07.010

#DBfeature #ICYMI Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling By Agnese Kocere, Alexa Burger, et al. tinyurl.com/2rcuyhvy

One week away! New season of DevBioConnect Author Seminar begins on September 16, 2026 EST 12:00–1:00 PM Dr. David Paulding On Cranial Neural Crest www.sciencedirect.com/science/arti... Dr. Neha Ahuja On Renal Pericyte www.sciencedirect.com/science/arti... Register👇 forms.gle/m14hJGbU2V8c...

#DBfeature #LatestResearch 🪰 Drosophila eye development is compromised by dTet overexpression through altered retinal determination gene expression By Malak Kleit, Sarah Mantash, Abdullah El-Kurdi, Jawdat Sandakly, Margret Shirinian, et al doi.org/10.1016/j.ydbio.2026.07.006

#DBfeature #ICYMI Unusually high prevalence of cervical ribs in an 18th-Century Hungarian town: The impact of a tuberculosis epidemic on homeotic shifts during pregnancy By F Galis, AEA van der Geer, TJM Van Dooren, T Szeniczey, T Hajdu, K Kiss, I Pap tinyurl.com/yc8jjkft

#DBfeature #LatestResearch SFRP1 loss reveals mesenchymal mechanisms underlying abnormal lung maturation via Wnt and PDGF signaling By Nooralam Rai, Tina Zelonina, Kiran Chada, Jeanine D'Armiento doi.org/10.1016/j.ydbio.2026.06.011

#DBfeature #ICYMI Teaching the complexities of biological sex determination with the goal of creating a more inclusive classroom and perhaps challenging key components of the oversimplified rhetoric of the gender binary By Rebecca Delventhal tinyurl.com/53y96td5

New season of DevBioConnect Author Seminar begins on September 16th, 2026 EST: 12:00–1:00 PM Dr. David Paulding On Cranial Neural Crest www.sciencedirect.com/science/arti... Dr. Neha Ahuja On Renal Pericyte www.sciencedirect.com/science/arti... Register here👇 forms.gle/m14hJGbU2V8c...

#DBfeature #LatestResearch 🪰 Shared candidate genes associated with variation in egg size in cold-adapted and artificially selected Drosophila melanogaster By Intisar Koch, Taylor Beagle, Tyler Hayes, Cecelia Miles, et al doi.org/10.1016/j.ydbio.2026.06.015

#DBfeature #ICYMI Scarecrow, a homolog of mammalian Nkx2.1, regulates the temporal progression and glial differentiation of medulla neuroblasts for the optic lobe development in Drosophila melanogaster By Cheol-Ho Yun, Kyungjun Seok, Gyunghee G. Lee, Jae H. Park, Siuk Yoo tinyurl.com/3zz6rfnv

#DBfeature #LatestResearch Perturbing pH dynamics after zebrafish larval tail amputation impairs regeneration, which is rescued by GSK3 inhibitors. By Cambria Chou-Freed, Christopher Prinz, Anush Margaryan, Julie Theriot, Daniel Wagner, Diane Barber doi.org/10.1016/j.ydbio.2026.07.004

#DBfeature #ICYMI A comparative analysis of VEGF and its receptors revealed tissue-specific disruptions in angiogenic signaling and endothelial integrity in Hmox1-deficient mouse embryos By Meenakshi Rana, Gouri Nandi, Sidhant Jain, Divya Bajaj tinyurl.com/4dcw5aph

#DBfeature #LatestResearch Novel functional and molecular aspects of Hox/TALE in the context of different animal model systems and regulatory pathways discussed at a March 2026 workshop By Samir Merabet, Dorothea Schulte doi.org/10.1016/j.ydbio.2026.07.007

#DBfeature #LatestResearch The molecular mechanism underlying melatonin-mediated repair of ovarian damage in mice exposed to abnormal light cycles By F Zhang, R Ma, Y Jin, K Wang, H He, F Wang, G Zhang doi.org/10.1016/j.ydbio.2026.06.014

#DBfeature #ICYMI The patterning and proliferation roles of Shh are partitioned on distinct exosomes: Shh-P150 drive neural tube patterning, Shh-P450 promotes proliferation By Ankita Walvekar, Shivangi Pandey, Siddhesh Kamat, Raj Ladher, Neha Vyas tinyurl.com/46sajrdd

#DBfeature #ICYMI Mice with Fsp1-driven PDGFRβ hyperactivation develop cataracts, with rapid and complete lens opacification by 15 weeks. By Jesse Reardon, Yixuan Ma, Heather Chandler, Gina Sizemore, et al. tinyurl.com/2zhd9py7

#DBfeature #LatestResearch Developmental analysis of the cone photoreceptor-less little skate retina reveals distinct Onecut1 isoforms By Chetan Rangachar, Denice Moran, Mark Emerson doi.org/10.1016/j.ydbio.2026.06.010

#DBfeature #ICYMI Genetic knockout suggests Isl1 enhancer redundancy in mouse hindlimb development By Seth Olson, Yasuhiko Kawakami, et al. tinyurl.com/2jjje2sn

#DBfeature #LatestResearch 🪰 The Drosophila ovarian terminal filament imports lipophilic molecules that support cyst and follicle development within the ovariole By Bhawana Maurya, Allan Spradling doi.org/10.1016/j.ydbio.2026.06.013

#DBfeature #ICYMI The epigenetic factor CFP1 regulates BMP signaling during limb development, expanding and maintaining mesenchymal progenitors and initiating chondrogenesis. By Emanuele Pignatti, Lijie Jiang, Diana Carlone, et al. tinyurl.com/y3xevhew

#DBfeature #LatestResearch The vascular–osteogenic interface in craniofacial development: a structured review of emerging associations in congenital malformations By Karl Jacobs et al. doi.org/10.1016/j.ydbio.2026.06.012

#DBfeature #ICYMI H3K9me2-modified chromatin regions rearrange during mouse embryonic development to adopt cell type-specific configurations By Diana Fulmer, Emily Shields, Andrey Poleshko, Jonathan Epstein, Cheryl Smith tinyurl.com/3e4xutw8

#DBfeature #LatestResearch 🪰 Germline cysts require Ecdysone receptor for proper timing of encapsulation in the Drosophila ovary By Lindsay Swain, Daniel Phipps, Susannah Catherine Webster, Lauren Jung, Elizabeth Ables doi.org/10.1016/j.ydbio.2026.06.008

#DBfeature #ICYMI Intraocular vasculature formation precedes extraocular vasculature penetration of mouse eyes By Satoshi Imanishi, Yohei Tomita, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara tinyurl.com/y38awzd3

#DBfeature The duplication-degeneration-complementation model: A seminal framework for evolutionary retention of duplicated genes By Chris Amemiya doi.org/10.1016/j.ydbio.2026.06.006

#DBfeature #ICYMI 🐸 Identification, expression and function of 28 new candidate regulators of placodal neurogenesis in Xenopus laevis By Bertrand Hutlet, Gerhard Schlosser tinyurl.com/34szsky6

#DBfeature A tribute to Gail R Martin, mouse geneticist and mentor extraordinaire (April 12, 1944 - Feb 9, 2026) By Alexandra Joyner doi.org/10.1016/j.ydbio.2026.05.007

#DBfeature #ICYMI 🐸 MicroRNA miR-196a controls neural crest patterning by repressing immature neural ectoderm programs in Xenopus embryos By Alice Godden, Grant Wheeler, et al. tinyurl.com/4mne33bu

#DBfeature #LatestResearch 🧠 Microtubule binding protein Togaram1 is required for proper development of mammalian forebrain and neural primary cilia, with its knockout leading to a thin and irregular neuron layer By Clarissa Nassar, Savera Shetty, Noelle Dwyer doi.org/10.1016/j.ydbio.2026.05.011

#DBfeature #ICYMI Injury-induced Neuregulin-EGFR signaling from muscle mobilizes stem cells for whole-body regeneration in acoels By Brian Stevens, Riley Popp, Heather Valera, Kyle Krueger, Christian Petersen tinyurl.com/4h52at7f

#DBfeature #LatestResearch 🐣 Gene knockout in chick reveals a new in vivo role for Cxcl14 during trigeminal ganglion development By Hugo Urrutia, Junpeng Gao, Marianne Bronner doi.org/10.1016/j.ydbio.2026.06.001

#DBfeature #ICYMI 👁️ Unraveling the developmental heterogeneity of human retinal ganglion cells within the developing retina By Emil Kriukov, Jonathan Soucy, Everett Labrecque, Petr Baranov tinyurl.com/mtvnssdy

#DBfeature #LatestResearch 🧠🐁 Neurogenesis and gliogenesis in the developing neocortex are imbalanced in mice lacking the proteoglycan Tsukushi By Sabrina Quaresima, Valerio Licursi, Tenta Ohkubo, Giuseppe Lupo, et al. doi.org/10.1016/j.ydbio.2026.05.009

#DBfeature #ICYMI 🐠 Single, double, and triple mutant combinations reveal redundant and novel functions of scube genes during zebrafish development By Quoc Duy Tran, Peter D. Currie et al. tinyurl.com/3d8tj7sf

#DBfeature #LatestResearch 🐠 Skeletal remodeling is responsible for the foramen in the skull for the hyoid artery in zebrafish By Miki Iwasaki, Junpei Kuroda, Masanori Nakae, Hironori Wada doi.org/10.1016/j.yd...

#DBfeature #ICYMI 🪱 C. elegans sperm activation for fertilization requires robust activity of the TAT-5 lipid flippase By Katherine Maniates, Ann Wehman et al. tinyurl.com/5fu7c49e