Devani Romero Picazo

Devani Romero Picazo

@devaropica.bsky.social

Postdoc at @daganlab.bsky.social studying plasmid evolution, microbial pangenomes and adaptation to plant-associated lifestyle. CAU, Kiel.

21 followers17 following6 posts

By using phylogenetics, we show that most genes with homologs in both the plasmid and the chromosome have different evolutionary origins. Moreover, we identify related plasmids outside of the genus that are rather large.

Devani Romero Picazo Interestingly, plasmid LPP-1 harbours genes that are core in the genus pangenome. Most of these genes encode for transcriptional regulators, suggesting the integration of the plasmid in the host's regulatory network.

We show that the genomes of plant-associated Pantoea comprise two domesticated plasmids that are inherited vertically, just like chromosomes. We prove that the largest plasmid (LPP-1) replicates synchronously with the chromosome.

You are up to date.