Charles University Structural Bioinformatics Group

Czech biotech stands on stronger foundations than many still assume. Nearly 430 entities, CZK 97.5bn in annual revenue, and growing investor attention show real momentum. But further growth will depend on one thing: turning strong science into investable, scalable projects. #Biotech #Czechia

Artistic beauty of protein structures by @irinabezsonova.bsky.social

Now published in NSMB! Paper: doi.org/10.1038/s415... Full PDF: rdcu.be/fhBtI Overview of additions since the preprint👇 (1/5)

🌿 The Botanical Garden of Charles University’s Faculty of Science turns 250! Founded in 1775, it is one of Central Europe’s oldest university gardens. Join us for a special anniversary program 15–21 Sept 2025. 🎉 @unikarlova.cuni.cz @botanickazahradauk.bsky.social

today #3Dprint protein is ferritin (PDB: 6I36) available here: www.printables.com/model/141627...

Kickstarting our symposium “Protein Annotations in the age of AI” at UCL!

We opened Day 2 of our #CECAM flagship workshop in Prague with the CECAM director Andrea Cavalli, highlighting steered #MD, dynamical docking & the complexity of binding energetics, and the challenges ahead. 🚀 #CECAMinPrague @iocbprague.bsky.social @cecamevents.bsky.social @iocbtech.bsky.social

CATH turns 30 years old 🥳 They celebrate with a Symposium on September 16th! I'll be presenting our work: "An Atlas of Energetic Evolutionary Constraints Across Protein Families" Unbelievable selection of speakers! So if you are around London, you can register to attend: tinyurl.com/2pnk8hj5

The first day of our bioML symposium at @iocbprague.bsky.social went very well. It is amazing to see how fast this field is moving forward. Thanks to everyone for the fantastic talks! 🤖🧬

🚀 GPU-accelerated docking to P2Rank-predicted pockets

Fantastic to work with so many talented people! today at departmental conference of cell biology department of @sciencecharles.bsky.social . Many thanks to our guests from Israel for joining us and sharing their results and time with us

Congratulations! 🎉

🚀 Our paper on the updated PrankWeb, a web app for protein binding site prediction using P2Rank, is out in @narjournal.bsky.social. Now with docking integration! 👨‍💻 Try it: prankweb.cz 📄 Paper: doi.org/10.1093/nar/... 💻 GitHub: github.com/cusbg/prankweb Developed at @cusbg.bsky.social

I am #exhilarated to share that our new paper "LIGYSIS-web: a resource for the analysis of protein-ligand binding sites" is now published in @narjournal.bsky.social! After almost two years of development and more than 600 commits, LIGYSIS-web is out! 📜 : tinyurl.com/utges-LIGYSI...

Join us for the next #Bioinformatics seminar hosted by @sciencecharles.bsky.social and @mff.unikarlova.cuni.cz. Nora Martin from CRG : “How does the structure of a genotype-phenotype map shape variation and evolutionary processes?”. 📅 Wed, Apr 30 🕕 17:20 bioinformatics.cuni.cz/seminar

Back in July 2023 we organized a small bioML symposium at @iocbprague.bsky.social, and it turned out to be a very pleasant and successful event. This summer we are following up with a great line-up of speakers. Please register for free, deadline May 30. tinyurl.com/bioMLPrague25

3DSIG has now joined BlueSky!! Follow us there to keep building a strong community around the fields of Structural Bioinformatics and Computational Biophysics!

A new preprint from our lab at @fchupol.bsky.social

🧪🇨🇿 A reminder: there’s a starter pack with Czech science institutions and research labs. A bunch of new ones have joined Bluesky lately -- and some, like Charles University (@charlesuni.cuni.cz), have fully made the move here from the other place.

go.bsky.app/NaGFZwf

Joe et al. have a fresh preprint on the MARTINI simulations of the #ribosome. arxiv.org/abs/2503.21357

we continue 1st @elixircz.bsky.social PhD conference with keynote by Martin Čech from @iocbprague.bsky.social and Cesnet on usegalaxy.cz

1st @elixircz.bsky.social PhD conference at Telč on 27-28th March 2025 superthread.

🎉 #ELIXIRCZ celebrated 10 transformative years in life sciences! Thanks, everyone, for celebrating with us! 🥂 Cheers to a decade of growth & many more to come! #Science #Innovation #DataScience @elixir-europe.org www.elixir-czech.cz/news/10-year...

we continue 1st @elixircz.bsky.social PhD conference (I should made a hashtag - too late) with student presentations

We are grateful and fortunate to have Sameer Velankar, the head of @pdbeurope.bsky.social, to start first ever @elixircz.bsky.social phd conference. Thank you RSJ and @elixircz.bsky.social for general support!

we continue with keynote lecture by Sameer Velankar from @pdbeurope.bsky.social

1st @elixircz.bsky.social PhD conference just started with @majek.bsky.social invitation

🎉 ECCB is now on Bluesky! Follow us for: ✔️ Latest conference updates ✔️ Key dates and calls ✔️ Networking & collaboration opportunities Join the ECCB community! #Bioinformatics #DataScience #CompBio

🚀 Exciting news! We're organizing a @cecamevents.bsky.social Flagship Workshop on Quantum Chemistry in Drug Design in Prague, Sept 8–10, 2025! Join top experts from academia & industry. Few spots left for contributed talks! 📢 Apply now: www.cecam.org/workshop-det... #compchem #cadd #QM #CECAM

Everything comes to an end but memories remain!! We had a great 3DSIG/3DBioinfo event in "sunny" Barcelona this week!! I have enjoyed so much to help organising it & to have such great minds all together sharing science for 3 days!! Aufwiedersehen friends! For more science & friendships to come! ⭐

Happy to share our latest preprint. With NRGRank you can screen 1M in a day in a laptop (use our NEGSuite-Qt for that) - a billion compounds per day with our computational resources.

and key people behind establishment of the ELIXIR CZ setup

@elixircz.bsky.social is celebrating 10th anniversary today! Jiri Vondrasek is in his summary acknowledging Janet Thornton and her contribution to founding of Elixir. Thank you!

Registration is open until March 6th!!

🧪🧬🔬 Postdoc in Computational Structural Biology at the @biozentrum.unibas.ch & @sib.swiss in Basel, Switzerland. www.biozentrum.unibas.ch/open-positio... The position is initially funded for 3 years, possibility to start immediately. #StructurePrediction, #Bioinformatics, #Uniprot3D, #AI

🚨 Unravel BILLIONS of years of protein evolution! 🚨 How did protein structures emerge and evolve over deep time? Join @zachary-ardern in the next ProSE Seminar! 📅 March 11, 3PM GMT 🔗 tinyurl.com/prose-seminar2 #ProteinEvolution #StructuralBiology

ROCKET #Alphafoldology fitting to lowres CryoEM to get conformation along the way

Counterintuitive

Join us tomorrow to hear @peterskrinjar.bsky.social talk about 🌹 Runs N' Poses 🌹! Curious to hear your thoughts on how to keep up with benchmarking in this field.