CD-CODE is a comprehensive, manually-curated database for biomolecular condensates and proteins developed by Agnes Toth-Petroczy lab @tothpetroczylab.bsky.social @mpi-cbg.de
https://cd-code.org
#CDCODE has been just updated to v2.4!
(GIF represents us trying to keep up with and organize the data 🤫)
🔵 10 new condensates (incl. 3 infectious🦠)
🔵 400+ new condensate-protein connections
🔵 new #condensate modifiers #cmods and #condensatopathies 🩺
👀 the latest updates: cd-code.org/release
☀️v2.3 release is here!
#CDCODE has grown - we've added new entries, cleaned up duplicates, and refreshed the c-mods page view!
📋See more release details: cd-code.org/release
📬Stay in the loop about condensate news - subscribe to our newsletter: tinyurl.com/CD-CODEnews#IDP#RBP#DatabaseUpdate
CD-CODE v2.2 RELEASE is live🤩
Our #database grew:
💡10 new #condensates
💡639 new #condensate - #protein connections
💡107 new c-mods
💡10 new #condensatopathies
🟣Find your favorite condensate cd-code.org and 👀see more details about the #release: cd-code.org/release#cdcode#IDP#RBP#DatabaseUpdate
My first manuscript in MPI colours! With @tothpetroczylab.bsky.social, we show that AlphaFold PAE-derived contact probabilities are well calibrated to the fraction of true interface contacts across experimentally determined protein dimers.
www.biorxiv.org/content/10.6...
Our pre-holiday database update is live! 🎄CD-CODE v2.1 is here.
Adding
🎁 11 new condensates
🎁 276 new proteins
We now track a total of 13,983 condensate-protein relationships, plus 253 c-mods and 113 condensatopathies.
Dive into the data and see more details about the release: cd-code.org/release
CD-CODE 2.0 is now published in @narjournal.bsky.social 🤩
CD-CODE 2.0 stores #biomolecular#condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies
👀 doi.org/10.1093/nar/...
CD-CODE 2.0 is now published in @narjournal.bsky.social 🤩
CD-CODE 2.0 stores #biomolecular#condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies
👀 doi.org/10.1093/nar/...
CD-CODE is a great example of an interdisciplinary teamwork between computational and experimental biologists and software engineers! #Thankyou to all the authors of @tothpetroczylab.bsky.social, the biomolecular condensate community of @mpi-cbg.de, @hymanlab.bsky.social, and Dewpoint Therapeutics!
💡With a #relational structure, programmatic access #API and improved search capabilities, CD-CODE 2.0 easily integrates into #datascience and digital #biology workflows, broadening its versatility and creating connections between condensate biology and #therapeutic development.
🔗 cd-code.org
☀️summer is here -
and so is CD-CODE v1.10 release!🤩
💡CD-CODE has now 719 manually curated #condensates (and ~40% are #human associated!)
💡Check out new #condensates and updated #protein - condensate connections at cd-code.org#Bioinformatics#DatabaseUpdate#IDR#RNP#RBP#cdcode
The latest release was supported by the #condesathon joined by @mpi-cbg.de condensate community🤩
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
🚀 Exciting Opportunity 🚀
Do you have a passion for structural biology?
We're hiring at @PDBeurope! 🌟
Apply now to help annotate biological data 💻 🔬
🔗 embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
Closing date: April 6, 2025
#JobOpening#StructuralBiology#Bioinformatics#ScienceJobs#Hiring
🍃CD-CODE update v1.09 is here!🍃
👀Check out the new #biomolecular#condensates at cd-code.org
👀We're continuing to update #Protein - #condensate connections and resolve issues!
Join us to share your #condensate#expertise as a contributor: cd-code.org/signup#Bioinformatics#DatabaseUpdate#IDR
✨Winter CD-CODE update to v1.08!✨
❄️ New #biomolecular#condensates added (total ⚪: 680)
❄️ #Protein - #condensate connections updated
❄️ Species attributes fixed 🤩
👀Check the current version here: cd-code.org
Join us to become a contributor: cd-code.org/signup#DatabaseUpdate#Bioinformatics#IDR
If you are a PhD student and like protein disorder (or want to learn more), Birthe Kragelund @bbkrage.bsky.social and Kristian Strømgaard are organizing a PhD course on How IDPs work 🧶🧬🧪 Note the cost if you are not at a Danish university.
Details: phdcourses.ku.dk/DetailKursus...
Hello Bluesky! We're thrilled to announce an open PhD position on exploring controlling condensate membrane attachment and exocytosis! Collaborate across Europe in the ComeInCell EU network. Apply now! Details: www.comeincell.org & www.ru.nl/en/working-a...
Biomolecular condensate starter pack!
Trying to compile & to bring together biomolecular condensate enthusiasts & critics!
Please join this non-exhaustive (sorry!) collection & just ping me for addition.
#condensates, #phaseseparation, #granules, #IDPsgo.bsky.app/NFqmffa
The Martin lab has an open postdoc position at the interface of #cytoskeleton and #condensate biology, in a fantastic research community!
If interested, do not hesitate to contact us: mocel.unige.ch/research-gro...
Please RT!
🔊☎️Calling the hive mind of the #Condensate Community of #bluesky: Join us in curating the CD-CODE!
Do you have a favorite condensate or are researching some that are not yet in cd-code.org?
We want your input and expertise!🧠
🔗Easy sign-up here: cd-code.org/signup
and add a new condensate 🎦⤵️
🚨Condensate of the Month is Stress Granule!
#StressGranules (#SGs) are dynamically forming cytoplasmic condensates that form in response to various cellular stresses.
🤩In CD-CODE there are more than 10 species and more than 1300 #protein associations described for SGs.
Various species have different Stress Granule proteomes:
🔵Translationally stalled mRNAs,
🔵translation initiation factors,
🔵RNA-binding proteins, and
🔵non-RNA-binding proteins
are among the main constituents of SGs.
🍂🌿Latest #CDCODE release:
🥳Version 1.07 is here: cd-code.org
🌟We focused on improving #species attributions and updating missing #condensate features.
Help us with your condensate expertise!🧠
Join us to become a contributor: cd-code.org/signup