Delighted to see additional press coverage of @aiproteins.com' recently announced partnership with Astellas If you haven't seen it yet, check out this great article in Fierce Biotech 👇 www.fiercebiotech.com/biotech/aste...
Chris Bahl
Chris Bahl
@cdbahl.com
protein geek, founder and CEO of AI Proteins @aiproteins.com https://linkedin.com/in/cdbahl
1.3K followers84 following64 posts
Chris Bahl reposted
@aiproteins.com has entered a research collaboration and license agreement with Astellas Pharma to discover and develop de novo #miniprotein therapeutics Read the full announcement 👇 www.businesswire.com/news/home/20...
We signed a new research collaboration and license agreement! @aiproteins.com will design and optimize de novo #miniproteins to multiple targets, and Astellas Pharma will do development & commercialization. This division of labor will help get new medicines to patients with the urgency they deserve.
Exclusive: Astellas struck a deal with AI Proteins that could top $400M, betting on the startup’s AI-designed miniproteins.
Chris Bahl reposted
Researchers from @aiproteins.com introduce a streamlined workflow that could reshape how labs produce proteins at scale. The method tackles key bottlenecks across the entire protein production pipeline and is designed to be fully compatible with automation. Read more: zurl.co/kAHMW
We always strive for our work to substantially benefit the greater scientific community, and it's such a thrill every time it happens. A massive thank you to @addgene.bsky.social for amplifying the impact of researchers everywhere! 🧵👇
If you found this SUMO protease helpful, check out our latest publication which builds on it and makes it even better: onlinelibrary.wiley.com/doi/10.1002/... Hopefully another 100+ research labs around the world will benefit!
p.s. for the folks who live in #Boston, the beloved Citgo sign is almost back on top of @aiproteins.com headquarters at 660 Beacon St!
We always strive for our work to substantially benefit the greater scientific community, and it's such a thrill every time it happens. A massive thank you to @addgene.bsky.social for amplifying the impact of researchers everywhere! 🧵👇
This Blue Flame Award is for a plasmid encoding an improved SUMO protease enzyme, and it was the work of an amazing team: Kara Lau, Vladimir Baytshtok, Tessa Howard, Brooke Nickerson, JayLee Johnson, Lauren Carter, David Baker and Chris Lima www.jbc.org/article/S002...
Chris Bahl reposted
Replying to @proteinsociety.bsky.social
📄 Facile, high-throughput protein purification enabled by high-efficiency protease elution (Fig. 2) Read more here: onlinelibrary.wiley.com/doi/10.1002/...
Chris Bahl reposted
Chris Bahl reposted
🧬 Want to stay updated on protein science? Check out the @bpdmc.org monthly presentation series! Recent topics: • Computational antibody design • Energy-based models & structure • De novo small-molecule induced changes Learn more, watch past presentations, and join the community at bpdmc.org.
Chris Bahl reposted
Power up your protein purification with a new SUMO protease construct from @cdbahl.com and team! Find individual plasmids here: www.addgene.org/browse/artic... Or get the full benchmark set: www.addgene.org/kits/bahl-su...
The data, code, and detailed protocols are all available on github github.com/aiproteins/h... and all the plasmids are available on addgene www.addgene.org/233685/ www.addgene.org/233686/ www.addgene.org/kits/bahl-su...
Every protein designer knows that producing & testing designed proteins is a foundational capability for our field, & this is still pretty challenging for a lot of folks. This is why I'm delighted to share our work to make high-throughput protein production more accessible dx.doi.org/10.1002/pro....
The data, code, and detailed protocols are all available on github github.com/aiproteins/h... and all the plasmids are available on addgene www.addgene.org/233685/ www.addgene.org/233686/ www.addgene.org/kits/bahl-su...
Every protein designer knows that producing & testing designed proteins is a foundational capability for our field, & this is still pretty challenging for a lot of folks. This is why I'm delighted to share our work to make high-throughput protein production more accessible dx.doi.org/10.1002/pro....
Chris Bahl reposted
Chris Bahl reposted
Three weeks ago, we welcomed the local scientific community to join us at our headquarters in Kenmore Square for the inaugural lecture in the AI Proteins Seminar Series. Our speaker Neil King from @uwproteindesign.bsky.social delivered a superb seminar. Check it out 👇 youtu.be/OPRMfRnlx1k
Chris Bahl reposted
⏰ Tomorrow! Join our webinar, Introduction to Protein Design for Africa, featuring speakers from AI Proteins, STEAMulater, Minimal Bio, and Nostrum Biodiscovery. Learn how protein design is advancing innovation and accessibility around the world! Register: us06web.zoom.us/webinar/regi...
Chris Bahl reposted
Thank you to everyone who attended the inaugural lecture in the AI Proteins Seminar Series today. Neil King @kinglabipd.bsky.social gave a fantastic talk to a packed house!
Chris Bahl reposted
Chris Bahl reposted
Really fun and challenging (!) discussion with @cdbahl.com on BindCraft, the state of binder design, the oustanding challenges and perhaps also some misconceptions in the field 💫 www.healthtech.com/the-chain/ma...
I never imagined this would happen ~8+ years ago. Just, wow. I'm so grateful to everyone in this community and for all the support and help from the many people that made it possible.
We just passed an exciting milestone: our one thousandth member just joined @bpdmc.org! Thank you so much to everyone who has made this journey possible, and we're excited to welcome many more wonderful folks to our nerdy protein club! For more info, check out bpdmc.org
We've got two more positions open for RAs to join AI Proteins! One opening is for our Protein Characterization group led by Alyssa Anderson, and the other is for our Biochemistry group led by Edson Carcamo. These wet lab roles are a perfect for college students who are graduating this spring.
Our team is growing! We’re hiring for two new roles on our Biochemistry and Protein Characterization teams. These are hands-on, wet lab positions ideal for early-career scientists eager to make an impact and contribute to cutting-edge drug design. www.aiproteins.com/careers
We're recruiting a Research Associate to join our Bioprocess Development team. This is a wet lab role ideally suited for someone graduating college this spring who is excited to join a team pioneering a new therapeutic modality Check it out! 👇 www.aiproteins.com/open-positio...
I had a great time nerding out about protein design with @nickpolizzi.bsky.social, and an enormous thanks to @biotechtv.bsky.social and @massbio.bsky.social for hosting us! www.biotechtv.com/post/chris-b...
Speaking as someone who had a career in academia before industry - there are many things I love about academia, but my job satisfaction is higher in industry. I hope things get better for all my friends in academia, because switching isn't the solution for everyone. www.nature.com/articles/d41...
Chris Bahl reposted
We've got Jeff Gray (graylab.jhu.edu) coming to present this month!! Wednesday, February 25th 2026, starting at 7pm EST in Room 181, Building 68, @MIT "Antibody language models vs. biology; protein docking denoising diffusion models vs. physics" bpdmc.org
Thanks for the fun conversation Ingmar Schuster, and for the opportunity to share more about what we're building at @aiproteins.com! youtu.be/7O0s5AY46U0
I appreciate all the congratulations for our Series A! I also want to make sure we don't forget an important truth Funding is not the finish line. We're grateful for the resources we have, and my promise is that we'll continue to do everything in our power to make a difference
AI Proteins has closed a $41.5 million Series A financing to accelerate the development of de novo #miniproteins! The round was led by Mission BioCapital and SANTÉ, with robust participation from existing investors. See the official press release for details: www.businesswire.com/news/home/20...
The next chapter for AI Proteins @aiproteins.com is officially underway! I'm absolutely delighted to share that we’ve closed a $41.5M Series A led by Mission BioCapital and Santé Ventures. endpoints.news/boston-biote...
My new @ted.com talk from the main stage just went live! go.ted.com/chrisbahl 🧵👇
This is the foundation for our next chapter at @aiproteins.com. We’ve industrialized the process of creating #miniproteins de novo while fully controlling every aspect of their activity and properties.
My new @ted.com talk from the main stage just went live! go.ted.com/chrisbahl 🧵👇
My new @ted.com talk from the main stage just went live! go.ted.com/chrisbahl 🧵👇
Chris Bahl reposted
Join us in Room 181, Building 68 @mit.edu on October 22nd 2025 @ 7pm EDT to see @grocklin.bsky.social present a mind blowing amount of data and learn what becomes possible at this scale "Predicting protein folding stability and aggregation propensity using large-scale experiments" bpdmc.org
We're looking for a mass spec expert to join our team at @aiproteins.com! This position is ideal for a freshly-minted PhD grad (or someone who will graduate within the next 6 months or less), or a rockstar scientist who earned their skills on the job in biotech
We're #hiring a Scientist in Mass Spectrometry! Apply today or share this post with your network: www.linkedin.com/jobs/view/42... (ignore what linkedin says - the search is still open) Interested? Please email your CV to: careers@aiproteins.bio
Chris Bahl reposted
Congratulations to Dr. James Bowman on his promotion to Chief Technology Officer! www.businesswire.com/news/home/20...
I am overjoyed to announce that James Bowman has been promoted to Chief Technology Officer at @aiproteins.com! 🧵👇
As our first CTO at @aiproteins.com, James will lead the continued acceleration of our platform capabilities in addition to the design, testing and optimization of many novel #miniprotein drug candidates
It’s a privilege to be building @aiproteins.com together with James and our unbelievably talented and dedicated team of people, all striving to make a difference in the world through our technology www.businesswire.com/news/home/20...
I am overjoyed to announce that James Bowman has been promoted to Chief Technology Officer at @aiproteins.com! 🧵👇
James has been one of the key architects of this vision since day one, and his insight and leadership these past ~4 years has shaped the discovery engine that powers @aiproteins.com today
I am overjoyed to announce that James Bowman has been promoted to Chief Technology Officer at @aiproteins.com! 🧵👇
James joined my academic lab at the @ipiproteins.bsky.social in January of 2020 as a postdoc focused on #miniprotein de novo design and engineering. Less than 2 years later, James and I left academia together to found @aiproteins.com along with an incredible team of people from my former lab.
This was a lot of fun - thanks so much @yossefbaidi.bsky.social and @fang-xie.bsky.social for the great conversation, and for your passion and excitement for biotech and entrepreneurship!
During this episode, @fang-xie.bsky.social and I interview @cdbahl.com, co-founder and CEO of @aiproteins.com. We discuss with Chris his interest in protein science and how he started his academic lab at the @ipiproteins.bsky.social.