Billy Quilty

Billy Quilty

@bquilty.bsky.social

Infectious disease epidemiologist and modeller based at Charité Universitätsmedizin Berlin, honourary LSHTM | PhD LSHTM | MSc Imperial College London | Twitter: @BQuilty

1.3K followers1.7K following169 posts

"We show that a distributed botnet of IoT devices... could also provide enough compute to run a capable model." "We run Gemma4-26B-A4B, distributed over 15 inexpensive off-brand Android TV boxes (~$55 each)... at 0.39 tokens per second." www.anthropic.com/research/sel...

Billy Quilty@bquilty.bsky.social

There are already many rogue agents on the web - we've just previously called them computer viruses, or bots. A capable agent on OpenAI may not escape containment itself could rent server space, infect people's computers, etc., and create many more agents, then direct them to do nefarious things.

Will be interesting to see what "sticks" from this vibe-coded software revolution. It's clear that you can get to impressive ends really easily (just don't think about the means too much), but maintaining that is much more difficult (see all those "games in a browser" that worked - for about a day).

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Science is going the same way, with journals swamped by AI-accelerated research. Maybe we'll have fewer giants to stand on the shoulders of, and millions of ants instead?

But ants typically don't appreciate being stood on. However, they can do remarkable things when coordinated - who knows. ...probably pushed that metaphor to its limits.

Will be interesting to see what "sticks" from this vibe-coded software revolution. It's clear that you can get to impressive ends really easily (just don't think about the means too much), but maintaining that is much more difficult (see all those "games in a browser" that worked - for about a day).

And now as its so easy to spin up your own version, there's little incentive to contribute to larger open-source projects - but most maintainers of legacy projects are so vehemently anti-AI they won't accept any AI-assisted pull requests. But I guess what can you do given the likely deluge of PRs?

Billy Quilty reposted

I would have thought the development of something which is able to make the working class obsolete would be something the left would take more seriously, but nope its all BS apparently. Real head in the sand behaviour which will come back to bite us, big time.

There are already many rogue agents on the web - we've just previously called them computer viruses, or bots. A capable agent on OpenAI may not escape containment itself could rent server space, infect people's computers, etc., and create many more agents, then direct them to do nefarious things.

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A nice concept but seems a bit... obvious...? to be in Nature? Ah, it was first up on arxiv a year ago. Perhaps says a lot about how quickly things are progressing in the field that this seems less than revolutionary - like in COVID, journals will struggle to keep up arxiv.org/abs/2509.06917

arxiv.orgPaper2Agent: Reimagining Research Papers As Interactive and Reliable AI AgentsWe introduce Paper2Agent, an automated framework that converts research papers into AI agents. Paper2Agent transforms research output from passive artifacts into active systems that can accelerate dow...
Nature@nature.com

The AI agent can respond immediately to questions about the paper, providing a convenient way for scientists to grasp advances in unfamiliar fields go.nature.com/4xrHsLG

Regardless, it's good to see this stuff, perhaps indicative of a move towards papers being a dynamic interactive process rather than a static PDF. But also heralds the coming reproducibility crisis as hoards of agents attempt to run creaking GitHub code, finding plenty of bugs along the way...

Seeing a lot of pedantic hang-up on the phrasing of "AI could kill all humans". Yes full-on extinction is unlikely for a number of reasons, but there's a wide range of possibilities between 0 and 7 billion deaths that would still be very bad indeed

Billy Quilty reposted

Both the state and the free market have comprehensively failed on the availability of eclipse glasses. Where are they? It's not like we haven't known this was going to happen for hundreds - if not thousands - of years.

Billy Quilty reposted

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So not definitive (but 95% CrI is 53-91%, so more than pure chance). Cases we see from now on are more likely to be due to transmission beyond that from index case. Given serial interval It'll be a while before we can say anything about transmission happening off the ship (tho depending on context)

Billy Quilty reposted

When there's a new outbreak, yes there's always the possibility of a major pandemic and that puts some weight on the need for a fast, cooperative and effective public health response but really the immediate, foreseeable consequences of the outbreak should be the focus and are reason enough to act.

It would be beneficial if prominent public health voices could avoid solely framing outbreak risks through the lens of whether they should be something for people in high-income countries to "worry about" or not.

A great Perspective piece from @joelmossong.bsky.social on the evolution of social contact surveys, from the POLYMOD study he led in 2008 (which became the template for all others), to CoMix during the pandemic, and now on to Reconnect: journals.plos.org/plosmedicine...

journals.plos.orgOn the evolution of the company we keep: Implications for infectious disease modelingIn this Perspective, Joël Mossong discusses the importance of understanding social contacts and how they have evolved for infectious disease modeling, and the need to factor in additional consideratio...
Billy Quilty@bquilty.bsky.social

How have UK social contact patterns changed post-pandemic? How assortative are they by age, ethnicity, and socioeconomic status? Pleased to share our new @plosmedicine.org paper, jointly led by @lucygoodfellow.bsky.social and myself, with @kevinvzandvoort.bsky.social and John Edmunds. #IDSky

Billy Quilty reposted

How have social contact patterns changed since the #COVID-19 pandemic? In this cross-sectional survey, Lucy Goodfellow & colleagues collect information on social contacts of over 13,000 people in the UK post-pandemic, including social mixing by ethnic & socioeconomic groups🧪 #MedSky plos.io/4nmJyck

plos.ioSocial contact patterns in the United Kingdom following the COVID-19 pandemic: The Reconnect cross-sectional surveyIn a cross-sectional survey, Lucy Goodfellow and colleagues collect information from over 13,000 people on demographics and their social contacts after the COVID-19 pandemic in the UK.

Billy Quilty reposted

This Perspective by Joël Mossong discusses findings from the Reconnect study, highlighting the importance of understanding social contacts & how they have evolved for infectious disease modeling, & the need to consider ethnic & socioeconomic backgrounds🧪 #MedSky #COVID-19 plos.io/42CQPLI

plos.ioOn the evolution of the company we keep: Implications for infectious disease modelingIn this Perspective, Joël Mossong discusses the importance of understanding social contacts and how they have evolved for infectious disease modeling, and the need to factor in additional consideratio...
PLOS Medicine@plosmedicine.org

How have social contact patterns changed since the #COVID-19 pandemic? In this cross-sectional survey, Lucy Goodfellow & colleagues collect information on social contacts of over 13,000 people in the UK post-pandemic, including social mixing by ethnic & socioeconomic groups🧪 #MedSky plos.io/4nmJyck

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Finding 3: This social structure may drive observed infection inequalities. Using a next-generation matrix approach, we found that per-capita infection risk for a novel respiratory pathogen would be disproportionately higher for minority ethnic groups.

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Finding 1: People reported 9.1 daily contacts on average. This is around 20% lower than pre-pandemic levels seen in POLYMOD (2005-06), but about 40% higher than last reported by CoMix in late 2022.

Finding 2: Mixing is highly assortative. Beyond the expected age mixing, we found strong assortativity by ethnic group and socioeconomic status, particularly in home and workplace settings.

We ran the Reconnect social contact survey across the UK between November 2024 and March 2025. In total, 13,238 participants recorded their social contacts over a 24-hour period.

The current online dichotomy between "it's the next pandemic, panic" and "it's not, nothing to worry about" hides a wide spectrum of possible intermediate trajectories that would still present a real challenge if they played out.

As @tah-sci.com says, a "reasonable worst case scenario" could look something like some of the Ebola outbreaks we've seen in the past 15 years - slow-burning, spluttering chains of transmission in hard-to-manage low-resource settings: bsky.app/profile/tah-...

Thomas House@tah-sci.com

> Given this, a reasonable best case is no further infections and deaths. For a reasonable worst case, we could look to the larger Ebola outbreaks - not a major pandemic like COVID, but we do sometimes see extended epidemics of pathogens that are ultimately controlled. >

That's not to say that's what will happen, but it is in the range of possible outcomes. Of course we can make those futures less likely with effective control measures now.

Billy Quilty reposted

Not a fan of public health influencers promoting their outbreak 'scoops' and 'exclusives' very shortly before the official announcement would have been made anyway. Leaking fragments and out-of-context snippets of routine reports aren't doing anyone a public service.

Billy Quilty reposted