Arnone Lab

Arnone Lab

@arnonelab.bsky.social

Group established in 2000, studying echinoderms to unravel the evolution of organs and body parts by comparison of gene regulatory networks. https://arnonelab.it/

461 followers395 following33 posts

Arnone Lab
@arnonelab.bsky.social

(2/2) We also presented three posters: one by Olga Zueva and two featuring collaborations with Nacho Maeso’s and Carmen Andrikou’s labs. Ina was also invited earlier on to speak at the Amphioxus satellite meeting, where Olga gave a contributed talk as well. 👏🏻

Arnone Lab reposted

Michalis Averof
@michalis-averof.bsky.social

These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9

Arnone Lab reposted

Michalis Averof
@michalis-averof.bsky.social

Replying to @michalis-averof.bsky.social

Finding molecular tags that localise fluorescent proteins to the cell membrane was the goal of our latest paper, now published in Development @dev-journal.bsky.social. The tags act as address labels, sending proteins to the cell membrane, where they highlight the shape and arrangement of cells. 2/9

journals.biologists.comTargeting the cell membrane in established and emerging model organismsSummary: Screening a toolkit of diverse membrane-localising tags identifies candidates that efficiently localise proteins to the plasma membrane in a wide range of animals and choanoflagellates.

Arnone Lab reposted

em-hoc.bsky.social
@em-hoc.bsky.social

There are just a few days (and spots!) left to apply to this EM course with a focus on marine samples 🌊 do not miss it!

em-hoc.bsky.social@em-hoc.bsky.social

Don’t forget to apply to this beautiful Electron Microscopy course at @szndohrn.bsky.social in Napoli, Italy by February 12th! 🌊 ☀️ Stay tuned for the preliminary program, in the meantime take a look here: www.szn.it/index.php/it...

Arnone Lab reposted

Karel Mocaer
@karel-mocaer.bsky.social

We are excited to share that we are hosting a hands-on course on "Electron Microscopy of Marine Environmental Samples" 🔬🌊 📍Naples, Italy 🗓️ 8th-11th of April 2026 If you are interested, check the program below! Registration is open until the 12th of February. We look forward to seeing you there!

Arnone Lab reposted

imaeso.bsky.social
@imaeso.bsky.social

Our work on the evolution of the regulatory genome of echinoderms is now out in @natecoevo.nature.com. Led by my former PhD Marta Magri, Danila Voronov & Saoirse Foley. Great collaboration of Arnone, Hinman & Maeso labs, started long time ago with our missed José Luis Gomez-Skarmeta: rdcu.be/eXX8l

rdcu.beDeep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomesNature Ecology & Evolution - Analysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms...

Arnone Lab reposted

Dani Voronov
@danivoronov.bsky.social

I am extremely proud and happy to announce that another paper from my PhD days has just been published in @natecoevo.nature.com on evolution of genome and gene regulation thanks to all the amazing people involved. Check the paper out at: www.nature.com/articles/s41...

nature.comDeep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes - Nature Ecology & EvolutionAnalysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms and the long-term evolutionary dynam...
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Arnone Lab
@arnonelab.bsky.social

We here present two new genome assemblies for S. purpuratus and P. miniata, showing they are organized in TAD-like structures that, unlike vertebrates, are not built with CTCF. We also found deeply conserved cis-regulatory modules such as the one upstream of Tbx2/3, and we functionally evaluated it.

Arnone Lab
@arnonelab.bsky.social

I am deeply honored to share that my project NeurEvoFun has been awarded support from the Fondo Italiano per la Scienza (FIS), the Advanced Grant by the Italian Ministry of Education, Universities and Research, supporting fundamental research inspired by the ERC model. Excited for what’s ahead!

Arnone Lab
@arnonelab.bsky.social

These are the objectives we will pursue in NeurEvoFun (“Dissecting the neurosecretory brain-gut axis function and evolution: from regulome and cell identity to cellular crosstalk”).

Arnone Lab
@arnonelab.bsky.social

I am deeply honored to share that my project NeurEvoFun has been awarded support from the Fondo Italiano per la Scienza (FIS), the Advanced Grant by the Italian Ministry of Education, Universities and Research, supporting fundamental research inspired by the ERC model. Excited for what’s ahead!

Arnone Lab
@arnonelab.bsky.social

Beautiful course on electron microscopy coming soon in Naples, do not miss it!

em-hoc.bsky.social@em-hoc.bsky.social

The "Electron Microscopy Hands-On Course" returns for its 2nd edition in April 8-11, 2026, at the Stazione Zoologica Anton Dohrn in Naples, Italy. Explore the course overview and start your application here: www.szn.it/index.php/it...

Arnone Lab
@arnonelab.bsky.social

Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead! www.science.org/doi/10.1126/...

science.orgSingle-nucleus profiling highlights the all-brain echinoderm nervous systemA sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.
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Arnone Lab
@arnonelab.bsky.social

Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead! www.science.org/doi/10.1126/...

science.orgSingle-nucleus profiling highlights the all-brain echinoderm nervous systemA sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.

Arnone Lab reposted

Periklis Paganos
@perievodevo.bsky.social

Replying to @perievodevo.bsky.social

We discuss new research on sea urchins, how echinoderms remain relevant experimental systems in the multiomics era, and the future of the cell type evolution and development field.

Arnone Lab reposted

Periklis Paganos
@perievodevo.bsky.social

Thrilled to share my newest perspective article with @arnonelab.bsky.social in @dev-journal.bsky.social journals.biologists.com/dev/article/...

journals.biologists.comIn preprints: cell type-specific gene regulation through the lens of echinodermsOne of the most intriguing questions in developmental biology is how a single cell, the zygote, gives rise to hundreds or millions of distinct cell types during embryogenesis. Decades of research have...
Arnone Lab
@arnonelab.bsky.social

We‘re thrilled to be involved in this great open science initiative; @mlrusciano.bsky.social really enjoyed testing this tool in sea urchins!

Michalis Averof@michalis-averof.bsky.social

How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵 Check our latest preprint

biorxiv.orgA toolkit for testing membrane-localising tags across speciesTransgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...
Arnone Lab
@arnonelab.bsky.social

Very proud to be a part of this!

Arnau Sebé-Pedrós@arnausebe.bsky.social

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41...

Arnone Lab reposted

Zak Swartz
@zakswartz.bsky.social

Another terrific Developmental Biology of the Sea Urchin & Other Marine Invertebrates is done! Thank you to all attendees for sharing your awesome science, the co-organizers for their hard work, our sponsors, and @mblscience.bsky.social for being such a great venue. Photo credit to Bob Morris 👏

Arnone Lab reposted

mariacocurullo.bsky.social
@mariacocurullo.bsky.social

Excited to share our latest work! @arnonelab.bsky.social , @John Kirwan, @Ina Arnone. We investigated the impact of light on the phenotypic response to food in sea urchin larvae. Check it out here: www.frontiersin.org/journals/eco.... @szndohrn.bsky.social, #SZN, #seaurchin, #ecoevodevo

frontiersin.orgFrontiers | Phenotypic response to food availability in sea urchin larvae and impact of light during development and growth
Arnone Lab
@arnonelab.bsky.social

Amazing work from the group of my former colleague, for ever friend, Angela Falciatore and colleagues: the "pigment of imagination" rocks! Congratulations! 🎉🍾🥂

Angela Falciatore@afalciat.bsky.social

Excited to share this work from our lab @IBPC and collaborators! Thanks to diatoms, some of the mysteries surrounding phytochrome photoreceptors in the oceans are beginning to be unraveled! Phytochrome remains the "pigment of imagination’ Congratulations to all the authors! doi.org/10.1038/s415...

Arnone Lab reposted

bioRxiv Evolutionary Biology
@biorxiv-evobio.bsky.social

Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes https://www.biorxiv.org/content/10.1101/2024.11.30.626178v1

biorxiv.orgDeep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes https://www.biorxiv.org/content/10.1101/2024.11.30.626178v1 Despite the growing abundance of sequenced animal genomes, we only have detailed knowledge of regula
Arnone Lab
@arnonelab.bsky.social

Thrilled to share this new work resulting from a great collaboration of my lab with the labs of Ignacio Maeso and Veronica Hinman, started with the dear José Luis Gómez-Skarmeta many years ago. Take a look! www.biorxiv.org/content/10.1...

biorxiv.orgDeep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomesDespite the growing abundance of sequenced animal genomes, we only have detailed knowledge of regulatory organization for a handful of lineages, particularly flies and vertebrates. These two groups of...