Breaking trait scaling via the evolution and regulation of dimorphic decoupling in ants | PNAS www.pnas.org/doi/10.1073/...#Ants#Pheidole 🐜
@uottawa.ca@uottawascience.bsky.social
So proud of my lab mate @sagrill.bsky.social (whose on the job market 👀) for this magnum opus from @remlehmann.bsky.social lab @whiteheadinstitute.bsky.social ScRNA-seq of 🪰 germ cells reveals new biology, answers age old questions, and proposes new paradigms! 1/8
www.biorxiv.org/content/10.6...
Excited to share some of our new work on Queen and Worker caste determination in ants!! Especially, the surprisingly role early embryonic development plays!
🐜 Ant societies meet embryonic mechanics!
Join @arjunarajakumar.bsky.social and @surajshankar.bsky.social for two fascinating talks exploring caste determination and robust fate timing.
📅 Oct 2 | ⏰ 10 AM ET / 7 AM PT
🔗 Scan the poster’s QR code to join us and bring your questions!
#evodevo#dev
Thrilled to share the first full paper from @AntLabUNAM! 🐜💥
Our paper examines how queen and worker harvester ants differ in ovarian morphology and gene expression, shedding light on the ovary as a hub for multiple physiological systems, not just reproduction. Check it out! rdcu.be/ePNP8
Excited to share our new bioRxiv preprint! 🐜🧠🥳
We explore how age, social context, and neuromodulatory systems shape temporal polyethism in harvester ants.
If you’re at #IUSSI2026, stop by Carlos Zavaleta’s poster on Wednesday to hear more!
www.biorxiv.org/content/10.6...
So proud of my lab mate @sagrill.bsky.social (whose on the job market 👀) for this magnum opus from @remlehmann.bsky.social lab @whiteheadinstitute.bsky.social ScRNA-seq of 🪰 germ cells reveals new biology, answers age old questions, and proposes new paradigms! 1/8
www.biorxiv.org/content/10.6...
So proud of my lab mate @sagrill.bsky.social (whose on the job market 👀) for this magnum opus from @remlehmann.bsky.social lab @whiteheadinstitute.bsky.social ScRNA-seq of 🪰 germ cells reveals new biology, answers age old questions, and proposes new paradigms! 1/8
www.biorxiv.org/content/10.6...
Incredibly excited to share my new preprint! 🪰🧬
Ever wondered how germ cells can specify their fate without having a dedicated transcriptional program?
We found that germ cells keep the uncommitted chromatin state of the early embryo
www.biorxiv.org/content/10.6...
Lost children are the first germ cells to die during embryogenesis, they fail to undergo trans-epithelial migration and are lost in the gut. When we rescue their death with chk2 mutants they still retain maternal transcripts and do not express zygotic transcripts. 7/8
Always a pole cell never a pgc! Transcription may be essential to segregate healthy and defective pole cells. Pole cells that never activate their zygotic genome and retain what mommy gave them, die. Pole cells that activate their zygotic genome too much also die. Life is a balance! 8/8
As It turns out, nanos actually inhibits Zelda protein levels in pole cells! Now we find that pole cells in nanos mutants have a dramatic increase in Zelda protein. Nanos -> Zelda -> class II genes. This sheds new light for how nanos protects germline identity and prevents its somatization. 5/8
Finally, our data uncovered a second unexpected cluster of germ cells that we term lost children. These germ cells are isolated from the 9 to 12 hour AEL window as coalesced germ cells. These germ cells completely retain their maternal transcriptome and never activate zygotic gene expression. 6/8
We found that while these class II genes are expressed in pole cells, their translation is inhibited by nanos. Unexpectedly, when we examined class II transcription in nanos mutants we found a dramatic increase in their transcription!! 4/8
We discovered unexpected transcription during a developmental period when pole cells were long thought to be transcriptional quiescent. These class II genes are almost all intron-less and RNApol2 independent. 2/8
Polyphenism - one genome producing different forms - is common in eusocial insects. @arjunarajakumar.bsky.social explores the molecular basis for Pharaoh ant caste development. Queens produce two egg types, giving rise to fertile queens or sterile workers, & queen:worker changes over time. #2026SDB
After a brutal year from a horrific shoulder injury I am SO excited for #2026SDB in Las Vegas next week! @socdevbio.bsky.social It will be my first time going to the national SDB and can't wait to reconnect and meet new scientists! I will be presenting about #ants at the #HildeMangold symposium!
The elongated shape of the #Drosophila#wing is regulated by the Dachsous-Fat signalling pathway, but how? This study shows that mechanical forces regulated by this pathway modulate tissue-wide #cytoskeletal tension to orient growth during larval development @plosbiology.org 🧪 plos.io/4vp9EOh
DEADLINE APPROACHING! ⏰
Apply to Comparative Developmental Biology by July 28. This intensive two-week laboratory course is designed for graduate students in their second or later year of Ph.D studies and post-docs.
🔗 More info here: go.mbl.edu/CDB
Excited to host invited speaker Alexandra Joyner at #2026SDB in Las Vegas! 🎰🃏
Her research explores the genetic regulation of development and how signaling pathways shape tissue patterning and organ formation. 🧬✨
#devbio#developmentalbiology#genetics#SDB2026
I am so excited to announce that the Weber Lab will be opening in the Department of Anatomy, Physiology, & Cell Biology @ucdavisvetmed.bsky.social@ucdavis.bsky.social. We will be investigating the development and evolution of vertebra size, shape, and function. And yes, the jerboas are coming with!
Excited to share that our paper on Horizontal Gene Transfer is now out in its final form in @gigascience.bsky.social! 🥳 By analysing 163 high-quality ant genomes, we show that HGT from bacteria is widespread across the ants and likely has adaptive functions!
doi.org/10.1093/giga...
🐜📸: Alex Wild
🎉 Welcome to our newly elected PASEDB executive council members 2026😊
Yui Suzuki (Wellesley College, USA)
Veronica Hinman (Whitney Marine Lab, USA)
@anyimv.bsky.social (Duke U, USA)
@rebeizlab.bsky.social (U of Pittsburgh)
Jennifer Brisson (U of Rochester, USA)
@bruvellu.bsky.social (UFMG, Brazil)
🌟A central mission of #PASEDB is to foster networking, discussion, and a sense of community
We want to highlight new #EvoDevo labs in Pan-America. In our Newsletter June edition we highlight:
- Daniela J. Di Bella
- @patrickrohner.bsky.social
- Carolina Purcell Goes
Excited to announce the Arsenault Lab is launching this fall at Mississippi State! We'll be using ants as a model to tackle fundamental questions in evolutionary biology and evo-devo through genetics and genomics techniques. Please reach out if you're interested, or share with someone who might be!
✨ Excited to host invited speaker Roberto Mayor (@mayorlab.bsky.social) at #2026SDB in Las Vegas! 🎰🃏
His research explores morphogenesis, focusing on how cells migrate, interact, and generate diverse cell types during development. 🧬✨
#devbio
Incredibly excited to rejuvenate my scientific social network on Bluesky! Current and past research interests include germline immortality, protein folding and organelle remodeling during development. Looking forward to what lies ahead!
For my first post here, I am happy to share that our latest paper is out at #NAR. Thanks for the smooth and constructive reviewing process and the highlight #RNAbiology#TEsky#smallRNAs (1/8)
doi.org/10.1093/nar/...
Cells are strong & generate forces while interacting with their environment.
Traction Force Microscopy has been instrumental in measuring these forces, revealing the underlying mechanics. Let's explore pioneering papers in this 🧵by @onenimesa.bsky.social & @juliaeckert.bsky.social
NEW ISSUE ALERT!!! Check out the new Research, Outlook and Review Articles online now at Genes & Development.
Click on the link for more:
➡️ genesdev.cshlp.org/content/curr...
Want to be amazed by how a symbiont can be located at the center of a cell while still being an epibiont! Please read and be amazed by the symbiosis between Anaerameoba and sulfate-reducing bacteria!
Now out in Nature Communications (open access)! rdcu.be/dZGNe
(1/11)