Aging Journal

Aging Journal

@aging-us.bsky.social

Aging is dedicated to advancing our understanding of the biological mechanisms that drive aging and the development of age-related diseases. Visit our website at https://www.aging-us.com/ for the latest in aging research.

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Aging Journal
@aging-us.bsky.social

#PaperoftheDay: "Investigating the efficacy and toxicity of partial in vivo reprogramming as a rejuvenation intervention" DOI ⬇️ https://doi.org/10.18632/aging.206431 #Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing

doi.orgInvestigating the efficacy and toxicity of partial in vivo reprogramming as a rejuvenation intervention | AgingPartial reprogramming by cyclic expression of Yamanaka factors has been proposed as a rejuvenation strategy, yet evaluating tissue-specific responses and potential risks remains challenging. Here, we
Aging Journal
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✅ A recent essay published in Aging, “Misha Blagosklonny: a life of ideas,” explores his life, scientific legacy, and groundbreaking ideas on aging, hyperfunction, rapamycin, and longevity. 🔗 Summary: https://bit.ly/4iu38Dd #Blagosklonny #Aging #Longevity #Rapamycin #Lifespan

aging-us.orgMisha Blagosklonny’s Ideas Reshaped Thinking About Aging - Aging ResearchScientific progress often begins with questioning assumptions that have shaped a field for decades. Few researchers embodied this approach as strongly as Mikhail “Misha” Blagosklonny, an oncologist an...
Aging Journal
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#PaperoftheDay: "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span" DOI ⬇️ https://doi.org/10.18632/aging.204897 #Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing

doi.orgInhibiting NLRP3 signaling in aging podocytes improves their life- and health-span | AgingThe decrease in the podocyte’s lifespan and health-span that typify healthy kidney aging cause a decrease in their normal structure, physiology and function. The ability to halt and even reverse these
Aging Journal
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✅ A #Study published in #Aging shows that human Progerin, but not normal Lamin A, causes slower growth, genome instability, and reduced lifespan in yeast, establishing a model for studying premature aging. #Summary: https://bit.ly/4yMEUZs #Progeria #PrematureAging #Publishing

aging-us.orgProgerin Expression Creates a Yeast Model of Premature Aging - Aging ResearchA research paper published in Volume 18 of Aging titled “Modeling premature aging in yeast via the expression of Progerin,” developed a yeast model in which human Progerin and its normal counterpart, ...
Aging Journal
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🎧 Listen to our #PressRelease on the #Review "Metformin at the convergence of aging and longevity." https://bit.ly/4y31A7x #Aging #Podcast #Audio #SoundCloud #TrendingWithImpact #Metformin #Longevity #Research #OA #PeerReviewed #Journal #Publishing #Press

soundcloud.comMetformin Emerges as a Promising Candidate at the Intersection of Aging and LongevityBUFFALO, NY — August 26, 2026 — A new #review was #published in Volume 18 of Aging on August 10, 2026, titled “Metformin at the convergence of aging and longevity.” The review was authored by Jarra M
Aging Journal
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📈 #TrendingWithImpact: The #Review titled, "Metformin at the convergence of aging and longevity," was recently #Published in Volume 18. #PressRelease ⬇️ https://bit.ly/4qB63w1 #Aging #Metformin #Longevity #Research #OpenAccess #PeerReviewed #Journal #Publishing #Press

aging-us.netMetformin Emerges as a Promising Candidate at the Intersection of Aging and Longevity - Aging JournalA new review was published in Volume 18 of Aging on August 10, 2026, titled “Metformin at the convergence of aging and longevity.”
Aging Journal
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🧬 Aging is pleased to support the 11th ICSA Conference, Nov. 3–5, 2026, in South Korea. 🏆 Aging will also sponsor a $200 poster prize recognizing outstanding research during the conference. Learn more ⬇️ https://bit.ly/46XvHlB #Aging #CellSenescence #ICSA #Conference

aging-us.netAging Supports the 11th International Cell Senescence Association Conference - Aging JournalAging is pleased to support the 11th International Cell Senescence Association (ICSA) Conference, taking place November 3–5, 2026, at Seoul National University’s Siheung Convention Center in South Kor...
Aging Journal
@aging-us.bsky.social

#PaperoftheDay: "Human senescent fibroblasts trigger progressive lung fibrosis in mice" DOI ⬇️ https://doi.org/10.18632/aging.204825 #Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing

doi.orgHuman senescent fibroblasts trigger progressive lung fibrosis in mice | AgingCell senescence has recently emerged as a potentially relevant pathogenic mechanism in fibrosing interstitial lung diseases (f-ILDs), particularly in idiopathic pulmonary fibrosis. We hypothesized tha
Aging Journal
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✅ Read our #blog post about the #trendingwithimpact research, "Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study." #Summary ⬇️ https://bit.ly/4bDvp69 #aging #diet #epigenetics #research #publishing #oa

aging-us.orgStudy Identifies Foods That May Reverse Biological Age and Promote Healthy Aging in Men - Aging (Aging-US) ResearchIn a world where we are living longer but not always healthier, scientists are searching for ways to add life to our years, not just years to our lives. A recent study published in Aging (Aging-US), Volume 17, Issue 4, led by researchers at the National...
Aging Journal
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✅ Read our #blog post about the #researchpaper, tilted "DoliClock: a lipid-based aging clock reveals accelerated aging in neurological disorders." #Summary ⬇️ https://bit.ly/4hXI4F4 #aging #TrendingWithImpact #research #agingclocks #schizophrenia #autism #downsyndrome #oa

aging-us.orgDoliClock: A Lipid-Based Clock for Measuring Brain Aging - Aging-US ResearchA new study published recently as the cover of Aging Volume 17, Issue 6, describes a new method to estimate how fast the brain is aging. By analyzing lipids, or fat molecules, in brain tissue, researchers from the National University of Singapore and Ha...
Aging Journal
@aging-us.bsky.social

🎧 Listen to our #PressRelease on the #Research paper, titled "Investigating POLG-driven modulation of cancer stemness: a pilot study in breast cancer cells." https://bit.ly/4hRLlWd #Aging #Podcast #Audio #SoundCloud #PaperSpotlight #BreastCancer #StemCells #POLG #OA #Press

soundcloud.comTargeting POLG Reduces Breast Cancer Stemness Through Mitochondrial DysfunctionBUFFALO, NY — August 24, 2026 — A new research paper was published in Volume 18 of Aging on August 8, 2026, titled “Investigating POLG-driven modulation of cancer stemness: a pilot study in breast can
Aging Journal
@aging-us.bsky.social

🔆 #PaperSpotlight: The #Research paper, titled "Investigating POLG-driven modulation of cancer stemness: a pilot study in breast cancer cells," was recently #Published in Volume 18. #PressRelease ⬇️ https://bit.ly/4xjub8Y #Aging #BreastCancer #StemCells #POLG #OA #Publishing

aging-us.netTargeting POLG Reduces Breast Cancer Stemness Through Mitochondrial Dysfunction - Aging JournalA new research paper was published in Volume 18 of Aging on August 8, 2026, titled “Investigating POLG-driven modulation of cancer stemness: a pilot study in breast cancer cells.”
Aging Journal
@aging-us.bsky.social

✅ Explore our #blog post on: "The impact of long-term social housing on biconditional association task performance and neuron ensembles in the anterior cingulate cortex and the hippocampal CA3 region of aged rats." #Summary ⬇️ https://bit.ly/4pFlCSM #aging

aging-us.orgHow Long-Term Social Connection Supports Brain Health and Memory in Aging - Aging-US ResearchAs people age, it is common to experience some memory lapses or slower thinking. Although this is often a normal part of aging, it can still affect a person's quality of life. Scientists have been investigating ways to slow or prevent cognitive decline,...
Aging Journal
@aging-us.bsky.social

#PaperoftheDay: "Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?" DOI ⬇️ https://doi.org/10.18632/aging.204920 #Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing

doi.orgTowards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases? | AgingBoth individuals taking rapamycin, an anti-aging drug, and those not taking it will ultimately succumb to age-related diseases. However, the former, if administered disease-oriented dosages for a long
Aging Journal
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🧬 #BehindtheStudy: Dr. Josh Mitteldorf summarizes his #research perspective #published in Volume 17, Issue 5, titled “Methylation clocks for evaluation of anti-aging interventions.” 🎥 https://www.youtube.com/watch?v=efgNvr5ezTk #author #interview #aging #methylation #agingclocks #publishing #oa

aging-us.netBehind the Study: Using Methylation Clocks to Evaluate Anti-Aging Interventions - Aging (Aging-US) AuthorsDr. Josh Mitteldorf summarizes his research perspective published in Volume 17, Issue 5 of Aging (Aging-US), titled “Methylation clocks for evaluation of anti-aging interventions.”
Aging Journal
@aging-us.bsky.social

🎧 Listen to our #PressRelease on the #Research paper "Hypomagnetic fields modulate lifespan, physical ability and mitochondrial metabolism in a Pink1 model of neurodegeneration." https://bit.ly/3W2n5YC #Aging #Podcast #Audio #SoundCloud #TrendingWithImpact #Publishing #OA

soundcloud.comHypomagnetic Fields Extend Survival but Reduce Mobility in Fly Model of Parkinson’s DiseaseBUFFALO, NY — October 22, 2026 — A new #research paper was #published in Volume 18 of Aging on September 23, 2026, titled “Hypomagnetic fields modulate lifespan, physical ability and mitochondrial met
Aging Journal
@aging-us.bsky.social

📈 #TrendingWithImpact: #Research paper, "Hypomagnetic fields modulate lifespan, physical ability and mitochondrial metabolism in a Pink1 model of neurodegeneration," published in Volume 18. #PressRelease ⬇️ https://bit.ly/4dUtqeO #Aging #Longevity #Parkinsons #OA #Publishing

aging-us.netHypomagnetic Fields Extend Survival but Reduce Mobility in Fly Model of Parkinson’s Disease - Aging JournalA new research paper was published in Volume 18 of Aging on September 23, 2026, titled “Hypomagnetic fields modulate lifespan, physical ability and mitochondrial metabolism in a Pink1 model of neurode...
Aging Journal
@aging-us.bsky.social

Honoring the Life and Legacy of Dr. Mikhail (Misha) Blagosklonny: A pioneer in #Aging and #Cancer research whose work transformed the field. His #Legacy will continue to inspire. Learn more about his extraordinary contributions: 🔗 https://bit.ly/44XLG29 #Geroscience #Research

Aging Journal
@aging-us.bsky.social

🧬 Aging is proud to sponsor the Future of Aging Research (FAR) Mixer 2026, hosted by the Aging Initiative at Harvard University, on Thursday, November 12, in Boston. Learn more and register ⬇️ https://luma.com/orv3bb20 #Aging #HealthyAging #Longevity #Research #Harvard

luma.comFuture of Aging Research (FAR) Mixer 2026 · LumaThe Future of Aging Research (FAR) Mixer 2026, hosted by the Aging Initiative (aging-initiative.org), aims to bring together undergraduate and graduate student...
Aging Journal
@aging-us.bsky.social

✅ Coordinating both hands relies on the brain’s ability to control movement. A new study in Aging found that older adults adapt brain activity during complex tasks, revealing how the brain supports movement with age. #Summary ⬇️ 🔗 https://bit.ly/4fn8XPz #Aging #Neurology #OA

aging-us.orgBrain Flexibility Is Linked to Hand Coordination During Aging - Aging ResearchCoordinating both hands is something most people take for granted. Everyday activities such as buttoning a shirt, preparing a meal, driving, or using a knife and fork all depend on the brain's ability...
Aging Journal
@aging-us.bsky.social

🧬 Aging is pleased to support the 11th ICSA Conference, Nov. 3–5, 2026, in South Korea. 🏆 Aging will also sponsor a $200 poster prize recognizing outstanding research during the conference. Learn more ⬇️ https://bit.ly/46XvHlB #Aging #CellSenescence #ICSA #Conference

aging-us.netAging Supports the 11th International Cell Senescence Association Conference - Aging JournalAging is pleased to support the 11th International Cell Senescence Association (ICSA) Conference, taking place November 3–5, 2026, at Seoul National University’s Siheung Convention Center in South Kor...
Aging Journal
@aging-us.bsky.social

🛡️ To maintain #scientificintegrity and reduce the risk of costly settlements related to image fraud, we recommend institutions subscribe to image forensics tools, establish dedicated image forensics teams, and encourage researchers to screen their manuscripts before publication.

Aging Journal
@aging-us.bsky.social

#PaperoftheDay: "From hyperfunction to systemic amplification: reframing the logic of late-life rejuvenation" DOI ⬇️ https://doi.org/10.18632/aging.206430 #Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing

doi.orgFrom hyperfunction to systemic amplification: reframing the logic of late-life rejuvenation | AgingAging is often modeled, and interventions prioritized, as the near-linear accumulation of cell-intrinsic lesions; yet the exponential acceleration of late-life mortality under the Gompertz law points
Aging Journal
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👀 Watch and subscribe to Aging’s #YouTube channel for author #interviews and abstract #videos: Our Channel ⬇️ https://www.youtube.com/@Aging-US #aging #authors #researchers #openaccess #insight

youtube.comAging-USThe mission of Aging-US is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing d...
Aging Journal
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🔆 #PaperSpotlight: A new #Review was published on September 19, titled “mTOR signaling in aging: from causality to geroprotective interventions and hallmark-level outcomes.” 🔗 https://bit.ly/4yrhMiR #Aging #Quote #mTOR #Rapamycin #Longevity #Geroscience #OA #Publishing

Aging Journal
@aging-us.bsky.social

🎧 Listen to our #PressRelease on the #Review "mTOR signaling in aging: from causality to geroprotective interventions and hallmark-level outcomes." https://bit.ly/4sfDG7m #Aging #Podcast #Audio #SoundCloud #PaperSpotlight #mTOR #Rapamycin #OA #Publishing #Press

soundcloud.commTOR Signaling Emerges as a Key Regulator of Aging, Highlighting Need for Targeted InterventionsBUFFALO, NY — October 20, 2026 — A new #review was #published in Volume 18 of Aging on September 19, 2026, titled “mTOR signaling in aging: from causality to geroprotective interventions and hallmark-
Aging Journal
@aging-us.bsky.social

🎥 #AgingShort: Abstract #Video of a #Review published in Volume 18, titled "mTOR signaling in aging: from causality to geroprotective interventions and hallmark-level outcomes." 🔗 https://bit.ly/4yrhMiR #Aging #PaperSpotlight #mTOR #Rapamycin #Geroscience #OA #Publishing

Aging Journal
@aging-us.bsky.social

🔆 #PaperSpotlight: The #Review "mTOR signaling in aging: from causality to geroprotective interventions and hallmark-level outcomes" was recently published in Volume 18. #PressRelease ⬇️ https://bit.ly/47wbL9H #Aging #mTOR #Rapamycin #Longevity #Geroscience #OA #Publishing

aging-us.netmTOR Signaling Emerges as a Key Regulator of Aging, Highlighting Need for Targeted Interventions - Aging JournalA new review was published in Volume 18 of Aging on September 19, 2026, titled “mTOR signaling in aging: from causality to geroprotective interventions and hallmark-level outcomes.”
Aging Journal
@aging-us.bsky.social

#PaperoftheDay: "Associations between klotho and telomere biology in high stress caregivers" DOI ⬇️ https://doi.org/10.18632/aging.204961 #Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing

doi.orgAssociations between klotho and telomere biology in high stress caregivers | AgingAging biomarkers may be related to each other through direct co-regulation and/or through being regulated by common processes associated with chronological aging or stress. Klotho is an aging regulato
Aging Journal
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✅ Read our #Blog post about the #Research paper, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV." #Summary ⬇️ https://bit.ly/4gW9f2w #Aging #HIV #COVID #Tcells #OA #PeerReviewed #Journal #Publishing #MedEd

aging-us.orgTictock: A Single-Cell Clock Measures Immune Aging in Viral Infections - Aging-US ResearchAging reshapes the immune system in two fundamental ways: it alters the proportions of different immune cell types circulating in the blood, and it induces molecular changes within each individual cell. For years, researchers have struggled to disentang...
Aging Journal
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#PaperoftheDay: "Natural aging and ovariectomy induces parallel phosphoproteomic alterations in skeletal muscle of female mice" DOI ⬇️ https://doi.org/10.18632/aging.204959 #Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing

doi.orgNatural aging and ovariectomy induces parallel phosphoproteomic alterations in skeletal muscle of female mice | AgingThe loss of skeletal muscle strength mid-life in females is associated with the decline of estrogen. Here, we questioned how estrogen deficiency might impact the overall skeletal muscle phosphoproteom
Aging Journal
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✅ Explore our #blog post on: "Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity." #Summary ⬇️ https://aging-us.org/2024/11/how-ai-and-longevity-biotechnology-are-revolutionizing-healthcare-for-healthier-longer-lives/ #Aging #Longevity #AI

aging-us.orgHow AI and Longevity Biotechnology are Revolutionizing Healthcare for Healthier, Longer Lives - Aging (Aging-US) ResearchAging research has made significant progress in recent years by combining disciplines like biology, technology, and medicine to tackle the challenges of extending healthspans and reducing age-related diseases. While people today live longer than ever be...