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What are some of the best DAGs you seen that depict time-varying confounding? Could be from a 'real' worked example, or generic. #EpiSky

I'm thinking in terms of visual depictions. If you include more than one time point and time-invariant confounders things get very messy very quickly.

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Here’s one I’m using for my PhD on the effect of opioid dose (TV exposure) on persistent opioid use in survivors of ICU. Pain, sedation, and analgesic adjuncts are all TV confounders, & age/sex/admission diagnosis are time-invariant confounders. Time is baseline (t0), t1… tN.

This is without any unmeasured confounders for quantitative bias analysis. It’s a deep, complex rabbit hole of chaos and spaghetti-looking DAGs!!