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Communications Biology
@commsbio.nature.com

It's #WorldSpaceWeek! 🧑‍🚀🛰️🔭 To celebrate, we're sharing 5 Comms Bio #microgravity papers that rocket-ed our world, selected by in-house editor Dr Michele Repetto 🚀✨👇 #WorldSpaceWeek2026

Communications Biology
@commsbio.nature.com

In the first paper, researchers wondered if life could begin in space: simulated microgravity revealed species-specific effects on sperm navigation, fertilization, and early embryo development, highlighting compensatory mechanisms and chemical cues critical for reproduction in future #spacemissions

doi.orgSimulated microgravity alters sperm navigation, fertilization and embryo development in mammals - Communications BiologySimulated microgravity reveals species-specific effects on sperm navigation, fertilization, and early embryo development, highlighting compensatory mechanisms and chemical cues critical for reproducti...
Communications Biology
@commsbio.nature.com

In the second, genome-wide ribosome profiling showed that #Arabidopsis plants had a responsive translational mechanism that interacted with transcription in a coordinated manner in a simulated microgravity environment 🌱 doi.org/10.1038/s420...

doi.orgGenome-wide ribosome profiling reveals a dynamic translational landscape in Arabidopsis seedling roots under simulated microgravity - Communications BiologyGenome-wide ribosome profiling sheds light on the role of upstream ORFs and sequence features in the context of translational reprogramming under simulated microgravity in Arabidopsis.

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Communications Biology
@commsbio.nature.com

Next up, researchers used rs-fMRI to investigate human #brainconnectivity changes induced by prolonged microgravity in #cosmonauts before and after #spaceflight, with both persistent and reversible location-specific changes in connectivity observed 🧠🧑‍🚀 doi.org/10.1038/s420...

doi.orgProlonged microgravity induces reversible and persistent changes on human cerebral connectivity - Communications Biologyrs-fMRI is used to investigate human brain connectivity changes induced by prolonged microgravity in cosmonauts before and after spaceflight, with both persistent and reversible location specific chan...
Communications Biology
@commsbio.nature.com

#Spaceflight is associated with persistent #MHC class I suppression in astronauts, a mechanism linked to immune evasion in cancer and viral infection. In this Perspective, the authors discuss the risks of astronaut MHC-I suppression, future research directions and potential therapeutic approaches.

doi.orgLong-term major histocompatibility complex class I suppression in astronauts and clinical implications - Communications BiologySpaceflight is associated with persistent MHC class I suppression in astronauts, a mechanism linked to immune evasion in cancer and viral infection. This Perspective discusses risks, mechanisms and co...
Communications Biology
@commsbio.nature.com

Last, but certainly not least, a Review by Coleine et al. highlights how #extremophile microbiomes and synthetic biology approaches could support Martian terraforming by driving biogeochemical cycles, regolith transformation, and future life-support ecosystems 🦠 doi.org/10.1038/s420...

doi.orgThe role of extremophile microbiomes in terraforming Mars - Communications BiologyThis Review highlights how extremophile microbiomes and synthetic biology approaches could support Martian terraforming by driving biogeochemical cycles, regolith transformation, and future life-suppo...