Really cool paper @embojournal.org showing the trade-off between oxidative phosphorylation and anti-microbial peptide (AMP) production in murine intestinal Paneth cells: link.springer.com/article/10.1... 🧪
link.springer.comReactive oxygen species stimulate Paneth cell plasticity and diminish antimicrobial function - The EMBO JournalThe gut epithelium faces constant environmental oxidative stresses. How it responds to pathological reactive oxygen species (ROS) is not fully understood. Using Paneth cell (PC) lineage reporters and ...
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