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Amazing physical chemical analysis of chromosome condensation and decondensation from Andrew Beel, PJ Mattei, and Roger Kornberg. I was tickled to see some expressions that I am used to from Roger's writing in the paper www.science.org/doi/10.1126/...

science.orgThe eukaryote chromosome, a two-state system with interconversion by a volume phase transitionThe formation of metaphase chromosomes requires the activity of condensins, DNA translocases that reduce chromosomal length through the process of loop extrusion. Reduction of length, however, does no...

Hannes

@hwitt.bsky.social

2 Sept

I cited the preprint a couple of years ago. I wonder what happened between the preprint coming out 5 years ago and now.

Craig Kaplan

@triggerloop.bsky.social

2 Sept

Wow- I hadn’t realized. I also maybe am surprised they didn’t update the preprint in that time!

Hannes

@hwitt.bsky.social

2 Sept

It caused a weird thing where the publication about the phenomenon comes out two years after our study on the impact of that phenomenon on chromosome mechanics www.nature.com/articles/s41...