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We welcome the first ever #MegabaseSpark submission, from @emcrae.bsky.social: "Systematic probing of RNA fitness landscapes" (detail in reply) Like and repost if you like this idea! #SynBio #RootPath

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"We’re building a synthetic library of RNA sequence variants to map how mutations reshape RNA folding and function. By encoding thousands of designed variants in synthetic DNA, we aim to uncover design rules for RNA-based therapeutics and nanostructures."