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Nature Communications
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Researchers @vai.org reveal how RNA binding remodels autoinhibited ZNFX1 assemblies and activates the helicase for ATP-dependent RNA unwinding

dlvr.itCryo-EM structures of autoinhibited and RNA-activated ZNFX1 helicase - Nature CommunicationsZNFX1 is an RNA helicase that plays a critical role in host defense against viral infections. Here, the authors reveal how RNA binding remodels autoinhibited ZNFX1 assemblies and activates the helicase for ATP-dependent RNA unwinding.

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