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I spent some time writing about a #rust library I've been working on: seqair, an alternative to (a subset of) htslib. This is a big one! So much potential API surface to cover and I better have a good reason for it! deterministic.space/seqair.html

Awesome write up, thanks for sharing it! Love the slab idea. I’ll have to try it out in perbase as that’s the exact access pattern that should speed it up a bit. How did using Tracey go for you? Was kt worth the effort?

Let me know if you try it! Tracey has been pretty nice to work with but I’ve mainly used it to write some basic specs myself and then to keep claude in check 😄 I’m sure I overdid it even and it’s too specific now!

For the most read-data heavy path in perbase, seqair is ~1.5x faster, which is awesome! I need to explore with some more datasets, but that's a pretty awesome win right off the bat.