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I spent some time writing about a #rust library I've been working on: seqair, an alternative to (a subset of) htslib. This is a big one! So much potential API surface to cover and I better have a good reason for it! deterministic.space/seqair.html

deterministic.spaceSeqair, my Rust-native take on htslibThis post introduces seqair , a new Rust library for bioinformatics formats I’ve been working on. We’ll look in detail at one of my main design choices here, a columnar store for iterating BAM data, …

Pascal

@killercup.de

I saw a bunch of posts about rewrites.bio etc about porting stuff to Rust by @robp.bsky.social for example. Maybe this is a trend, but at least I haven't seen htslib mentioned, probably because it is already really fast and good!

rewrites.biorewrites.bio - A manifesto for bioinformaticsPrinciples for responsible AI-assisted rewriting of bioinformatics tools.

30/4/26, 5:47 pm0 reposts1 like

Benjamin Schuster-Böckler

@dagams.bsky.social

1 May

💯 htslib is so fundamental to so many NGS applications. Having an equivalent API but with a cleaner backing is exactly what we need to accelerate development in this space. Thanks again for putting that work in, really great to see how work on rastair has positive impact far beyond its scope